Pharmacy Lecture: Sepsis and Septic Shock

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What laboratory tests should be performed to evaluate infection or complications of sepsis?

Complete Blood Count with differential, coagulation parameters, comprehensive metabolic panel, serum lactate, and arterial blood gas

What is the hallmark treatment of septic shock?

Rapid antibiotic administration and fluid resuscitation

What is the primary goal of fluid therapy in septic shock?

To restore intravascular volume depletion

What is the recommended first-line fluid for resuscitation in septic shock?

Crystalloids

What is the suggested target for glycemic control in septic shock?

Glucose levels between 140 and 180 mg/dL

When should vasopressors be used in septic shock?

After restoration of intravascular volume

What is the recommended initial dose of crystalloid for hypotension or lactate ≥4 mmol/L?

30 mL/kg balanced crystalloid

What is the suggested fluid in patients who received large volumes of crystalloids?

Albumin

When should intravenous hydrocortisone be considered in septic shock?

In patients who remain hemodynamically unstable despite adequate fluid resuscitation and vasopressor support

What is the target mean arterial pressure (MAP) in patients with septic shock refractory to fluid resuscitation?

MAP of 65 mmHg

This quiz covers the lecture on Sepsis and Septic Shock in Clinical Pharmacy, including the FAST HUG approach, feeding, and thromboembolic prophylaxis. It is intended for students of Pharmacy

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