Sepsis and Septic Shock Quiz

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Questions and Answers

What is the definition of bacteremia?

  • The presence of viable bacteria in blood (correct)
  • Sepsis associated with organ dysfunction, hypoperfusion or hypotension
  • The presence of microorganisms in normally sterile host tissue
  • The systemic response to infection

What is sepsis?

  • The presence of viable bacteria in blood
  • The systemic response to infection (correct)
  • Sepsis associated with organ dysfunction, hypoperfusion or hypotension
  • The presence of microorganisms in normally sterile host tissue

What is severe sepsis?

  • The systemic response to infection
  • Sepsis associated with organ dysfunction, hypoperfusion or hypotension (correct)
  • Sepsis with hypotension despite adequate fluid resuscitation, and perfusion abnormalities
  • The presence of microorganisms in normally sterile host tissue

What is septic shock?

<p>Sepsis with hypotension despite adequate fluid resuscitation, and perfusion abnormalities (C)</p> Signup and view all the answers

What is the first step in the management of sepsis?

<p>Obtaining cultures from blood, urine, sputum, etc. (A)</p> Signup and view all the answers

What is the minimum temperature that defines SIRS?

<p>&gt; 38 °C (D)</p> Signup and view all the answers

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Study Notes

Infection and Sepsis

  • Infection: presence of microorganisms in normally sterile host tissue.
  • Bacteremia: presence of viable bacteria in blood.
  • Sepsis: systemic response to infection.
  • Severe Sepsis: sepsis associated with organ dysfunction, hypoperfusion, or hypotension.
  • Septic Shock: sepsis with hypotension despite adequate fluid resuscitation and perfusion abnormalities.

SIRS (Systemic Inflammatory Response Syndrome)

  • Exaggerated systemic inflammatory response to severe clinical insults.
  • Manifested by 2 or more of the following conditions:
    • Temperature >38 °C
    • Heart rate >90 beats/min
    • Respiratory Rate >20 breaths/min
    • WBC >12,000 (Leukocytosis)

Management of Sepsis

  • Obtain cultures (blood, urine, sputum, etc.) prior to administration of antibiotics.
  • Administer broad-spectrum IV antibiotics within 1 hour.
  • Initial fluid resuscitation of 30 mL/kg crystalloid for hypotension or lactate >36 mg/dL (≥4mmol/L).
  • Vasopressors if MAP <65 mmHg.

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