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Questions and Answers
Which of the following are mechanisms of controlled release of a drug? (Select all that apply)
Which of the following are mechanisms of controlled release of a drug? (Select all that apply)
- Externally controlled mechanism (correct)
- Prodrug-based mechanism (correct)
- Swelling-controlled mechanism (correct)
- Reservoir-based dissolution-controlled mechanism (correct)
What are the criteria for a drug delivery system?
What are the criteria for a drug delivery system?
Criteria for a drug delivery system include mechanisms for controlled release.
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Study Notes
Criteria for a Drug Delivery System
- No information provided on the criteria for a drug delivery system.
Mechanisms of Controlled Release of a Drug
- Reservoir-based dissolution-controlled mechanism: involves a core of drug surrounded by a barrier that controls release.
- Matrix-based dissolution-controlled mechanism: drug is dispersed throughout a matrix that controls release.
- Reservoir-based diffusion-controlled mechanism: involves a core of drug surrounded by a membrane that controls release.
- Matrix-based diffusion-controlled mechanism: drug is dispersed throughout a matrix that controls release.
- Swelling-controlled mechanism: involves a material that swells in the presence of a solvent, controlling release.
- Osmosis-controlled mechanism: involves a material that releases a drug in response to osmotic pressure.
- Surface-erosion-controlled mechanism: involves a material that erodes from the surface, controlling release.
- Bulk-erosion-controlled mechanism: involves a material that erodes uniformly, controlling release.
- Prodrug-based mechanism: involves a prodrug that is converted to an active drug, controlling release.
- Externally controlled mechanism: involves an external stimulus that controls release.
Types of Release Systems
- No information provided on the types of release systems.
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