Pharmacy: Controlled Release of Drugs

Criteria for a Drug Delivery System

• No information provided on the criteria for a drug delivery system.

Mechanisms of Controlled Release of a Drug

• Reservoir-based dissolution-controlled mechanism: involves a core of drug surrounded by a barrier that controls release.
• Matrix-based dissolution-controlled mechanism: drug is dispersed throughout a matrix that controls release.
• Reservoir-based diffusion-controlled mechanism: involves a core of drug surrounded by a membrane that controls release.
• Matrix-based diffusion-controlled mechanism: drug is dispersed throughout a matrix that controls release.
• Swelling-controlled mechanism: involves a material that swells in the presence of a solvent, controlling release.
• Osmosis-controlled mechanism: involves a material that releases a drug in response to osmotic pressure.
• Surface-erosion-controlled mechanism: involves a material that erodes from the surface, controlling release.
• Bulk-erosion-controlled mechanism: involves a material that erodes uniformly, controlling release.
• Prodrug-based mechanism: involves a prodrug that is converted to an active drug, controlling release.
• Externally controlled mechanism: involves an external stimulus that controls release.

Types of Release Systems

• No information provided on the types of release systems.

This quiz covers the criteria for a drug delivery system and different mechanisms of controlled release of a drug, including reservoir-based and matrix-based dissolution-controlled mechanisms.