Pharmacy: Controlled Release of Drugs

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2 Questions

Which of the following are mechanisms of controlled release of a drug? (Select all that apply)

Externally controlled mechanism

What are the criteria for a drug delivery system?

Criteria for a drug delivery system include mechanisms for controlled release.

Study Notes

Criteria for a Drug Delivery System

  • No information provided on the criteria for a drug delivery system.

Mechanisms of Controlled Release of a Drug

  • Reservoir-based dissolution-controlled mechanism: involves a core of drug surrounded by a barrier that controls release.
  • Matrix-based dissolution-controlled mechanism: drug is dispersed throughout a matrix that controls release.
  • Reservoir-based diffusion-controlled mechanism: involves a core of drug surrounded by a membrane that controls release.
  • Matrix-based diffusion-controlled mechanism: drug is dispersed throughout a matrix that controls release.
  • Swelling-controlled mechanism: involves a material that swells in the presence of a solvent, controlling release.
  • Osmosis-controlled mechanism: involves a material that releases a drug in response to osmotic pressure.
  • Surface-erosion-controlled mechanism: involves a material that erodes from the surface, controlling release.
  • Bulk-erosion-controlled mechanism: involves a material that erodes uniformly, controlling release.
  • Prodrug-based mechanism: involves a prodrug that is converted to an active drug, controlling release.
  • Externally controlled mechanism: involves an external stimulus that controls release.

Types of Release Systems

  • No information provided on the types of release systems.

This quiz covers the criteria for a drug delivery system and different mechanisms of controlled release of a drug, including reservoir-based and matrix-based dissolution-controlled mechanisms.

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