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Questions and Answers
What is the primary goal of controlled-release products?
What is the primary goal of controlled-release products?
- To achieve and maintain optimum therapeutic blood levels of a drug (correct)
- To reduce the frequency of drug administration
- To prolong the duration of a drug's effects
- To achieve rapid therapeutic blood levels of a drug
What is the most common route of administration for modified-release products?
What is the most common route of administration for modified-release products?
- Parenteral
- Transdermal
- Oral (correct)
- Subdermal
What is a characteristic of non-oral rate-controlled drug delivery systems?
What is a characteristic of non-oral rate-controlled drug delivery systems?
- They are all administered through the skin
- They have a fixed duration of drug release
- They are only used for estradiol delivery
- They have a variable drug-release pattern (correct)
Which of the following non-oral controlled-release delivery systems has the longest duration of drug release?
Which of the following non-oral controlled-release delivery systems has the longest duration of drug release?
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Which of the following is an example of a non-oral controlled-release delivery system?
Which of the following is an example of a non-oral controlled-release delivery system?
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Study Notes
Controlled-Release Products
- Designed to release medication in a controlled manner, at a predetermined rate, duration, and location to achieve and maintain optimum therapeutic blood levels of a drug.
- The majority of modified-release products are orally administered, including tablets and capsules.
Non-Oral Controlled-Release Delivery Systems
- Include ocular, parenteral, subdermal, vaginal, and transdermal products.
- Release patterns vary in duration, including: • 24 hours for most transdermal patches • 3 months for the estradiol vaginal ring insert (Estring, Pharmacia & Upjohn) • 5 years for levonorgestrel subdermal implants (Norplant System, Wyeth-Ayerst)
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