Podcast
Questions and Answers
Which of the following neurotransmitters plays a primary inhibitory role in the body?
Which of the following neurotransmitters plays a primary inhibitory role in the body?
- Glutamate
- Histamine
- GABA (correct)
- Melatonin
Which receptor is primarily stimulated to produce sedation and/or anesthesia?
Which receptor is primarily stimulated to produce sedation and/or anesthesia?
- NMDA receptor
- GABA-A receptor (correct)
- a2-adrenergic receptor
- Melatonin receptor
What is the primary mechanism of action of ketamine?
What is the primary mechanism of action of ketamine?
- Inhibition of a2-adrenergic receptors
- Antagonism of NMDA receptors (correct)
- Positive allosteric stimulation of GABA-A receptors
- Stimulation of histamine H1 receptors
Which of the following drugs is not a positive allosteric stimulator of GABA-A receptors?
Which of the following drugs is not a positive allosteric stimulator of GABA-A receptors?
Which receptor is primarily antagonized to produce sedation and/or anesthesia?
Which receptor is primarily antagonized to produce sedation and/or anesthesia?
Which type of receptors are GABA-A receptors classified as?
Which type of receptors are GABA-A receptors classified as?
What is the primary excitatory neurotransmitter in the body?
What is the primary excitatory neurotransmitter in the body?
Which receptors are selectively activated by N-methyl D-aspartic acid?
Which receptors are selectively activated by N-methyl D-aspartic acid?
What type of receptors are GABA-B receptors classified as?
What type of receptors are GABA-B receptors classified as?
Which of the following is a target for nitrous oxide?
Which of the following is a target for nitrous oxide?
Which type of receptor is stimulated by dexmedetomidine to produce sedative, hypnotic, and analgesic effects?
Which type of receptor is stimulated by dexmedetomidine to produce sedative, hypnotic, and analgesic effects?
Which receptors are involved in the activity of biological clocks and their stimulation can induce sleep?
Which receptors are involved in the activity of biological clocks and their stimulation can induce sleep?
Which receptors are blocked by certain antihistamines and antidepressants to produce sedative effects?
Which receptors are blocked by certain antihistamines and antidepressants to produce sedative effects?
Which receptors are involved in the production of sedative, hypnotic, and analgesic effects via the stimulation of inhibitory neurons?
Which receptors are involved in the production of sedative, hypnotic, and analgesic effects via the stimulation of inhibitory neurons?
Which receptors are involved in sedative, hypnotic, and/or analgesic effects, and their stimulation can induce sleep?
Which receptors are involved in sedative, hypnotic, and/or analgesic effects, and their stimulation can induce sleep?
What is the primary advantage of benzodiazepines over barbiturates?
What is the primary advantage of benzodiazepines over barbiturates?
What is the primary concern when using benzodiazepines in combination with other CNS depressants?
What is the primary concern when using benzodiazepines in combination with other CNS depressants?
What determines the suitability of a benzodiazepine for treatment of anxiety versus insomnia?
What determines the suitability of a benzodiazepine for treatment of anxiety versus insomnia?
What is the primary mechanism of action of flumazenil?
What is the primary mechanism of action of flumazenil?
What is the recommended duration of benzodiazepine use to avoid dependence and withdrawal symptoms?
What is the recommended duration of benzodiazepine use to avoid dependence and withdrawal symptoms?
What is the primary mechanism of action of benzodiazepines on GABA-A receptors?
What is the primary mechanism of action of benzodiazepines on GABA-A receptors?
What is the primary mechanism of action of neurosteroids like alfaxalone?
What is the primary mechanism of action of neurosteroids like alfaxalone?
Which of the following agents is not a dissociative anesthetic?
Which of the following agents is not a dissociative anesthetic?
Which of the following receptors is targeted by baclofen, a muscle relaxant?
Which of the following receptors is targeted by baclofen, a muscle relaxant?
What is the effect of glutamate binding to NMDA receptors?
What is the effect of glutamate binding to NMDA receptors?
What is the primary effect of benzodiazepines on neuronal activity?
What is the primary effect of benzodiazepines on neuronal activity?
Which of the following drugs is an agonist of GABA-B receptors?
Which of the following drugs is an agonist of GABA-B receptors?
Which receptor is not primarily involved in the mechanism of action of neurosteroids?
Which receptor is not primarily involved in the mechanism of action of neurosteroids?
What is the administration route for ketamine and phencyclidine?
What is the administration route for ketamine and phencyclidine?
What is the primary mechanism of action of benzodiazepines in reducing anxiety?
What is the primary mechanism of action of benzodiazepines in reducing anxiety?
Which class of compounds, including barbiturates, has a greater depressant effect and is used routinely for anesthesia?
Which class of compounds, including barbiturates, has a greater depressant effect and is used routinely for anesthesia?
What is the effect of increasing chloride conductance and hyperpolarizing the neuron?
What is the effect of increasing chloride conductance and hyperpolarizing the neuron?
Which of the following agents enhances the actions of GABA by increasing the duration of channel opening?
Which of the following agents enhances the actions of GABA by increasing the duration of channel opening?
What is the mechanism of action of propofol?
What is the mechanism of action of propofol?
What is the primary use of barbiturates in modern medicine?
What is the primary use of barbiturates in modern medicine?
Which of the following is NOT a target for barbiturates?
Which of the following is NOT a target for barbiturates?
What is the effect of binding to distinct sites on GABA-A receptors?
What is the effect of binding to distinct sites on GABA-A receptors?
Which of the following is a characteristic of fluranes?
Which of the following is a characteristic of fluranes?
What is the primary mechanism of action of neurosteroids?
What is the primary mechanism of action of neurosteroids?
Which of the following is NOT a property of barbiturates?
Which of the following is NOT a property of barbiturates?
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