Pharmacology Quiz

What is the equation for Occupancy as derived in the text?

Occupancy = \frac{NA}{NTot} = \frac{xA}{xA - \frac{k-1}{k+1}}

Occupancy = \frac{NA}{NTot} = xA + \frac{k-1}{k+1}

Occupancy = NA = NTot \times xA \times \frac{xA + k-1}{k+1}

Occupancy = \frac{NA}{NTot} = \frac{xA}{xA + \frac{k-1}{k+1}} (correct)

What does the Law of Mass Action equation A + B → C + D represent?

A drug-receptor interaction

A cellular transport mechanism

An enzymatic process

A chemical reaction (correct)

What is the forward rate of reaction in the Law of Mass Action equation?

Forward Rate = k+1 [C] [D]

Forward Rate = k-1 [A] [B]

Forward Rate = k-1 [C] [D]

Forward Rate = k+1 [A] [B] (correct)

What is the backward rate of reaction in the Law of Mass Action equation?

Backward Rate = k-1 [C] [D] Signup and view all the answers

What does the drug-receptor interaction equation at equilibrium represent?

The balance between free receptor and agonist-receptor complex Signup and view all the answers

Write the equation reflecting Occupancy as defined in the text.

Occupancy = \rac{Number\ of\ Receptors\ Occupied},{Total\ Number\ of\ Receptors} Signup and view all the answers

Write the equation of the Law of Mass Action as presented in the text.

Forward\ rate\ of\ reaction: Forward\ Rate = k+1 [A] [B] ewline Backward\ rate\ of\ reaction: Backward\ Rate = k-1 [C] [D] ewline C + D Signup and view all the answers

Write the equation for Occupancy considering drug-receptor interaction at equilibrium as presented in the text.

Occupancy = \rac{NA},{NTot} = \rac{xA},{xA + \rac{k-1},{k+1}} Signup and view all the answers

Derive the equation for Occupancy as requested in the text.

Occupancy = NA = NTot xA xA + \rac{k-1},{k+1} Signup and view all the answers

What is the definition of an agonist according to the text?

An agonist is a drug which interacts with receptors; the resulting drug-receptor complex generates a response. Signup and view all the answers

Pharmacology Quiz

Questions and Answers

What is the equation for Occupancy as derived in the text?

What does the Law of Mass Action equation A + B → C + D represent?

What is the forward rate of reaction in the Law of Mass Action equation?

What is the backward rate of reaction in the Law of Mass Action equation?

What does the drug-receptor interaction equation at equilibrium represent?

Write the equation reflecting Occupancy as defined in the text.

Write the equation of the Law of Mass Action as presented in the text.

Write the equation for Occupancy considering drug-receptor interaction at equilibrium as presented in the text.

Derive the equation for Occupancy as requested in the text.

What is the definition of an agonist according to the text?

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