Pharmacology Quiz: Diuretics and Beta Blockers

Hydrochlorothiazide

• Thiazide diuretic used to treat hypertension and edema
• Usual dosage: 12.5 mg to 25 mg once daily
• Contraindicated in patients with anuria
• Cautious use in patients with a history of thiazide diuretic sensitivity
• Potential side effects: electrolyte disturbances, hyponatremia, photosensitivity, gastrointestinal distress

Lopressor

• Generic name: Metoprolol
• Beta 1 selective blocker indicated for hypertension, angina pectoris, and heart failure
• Usual dosage: 50 to 100 mg, maximum daily dose of 450 mg
• Contraindicated in patients with greater than first-degree heart block
• Use caution in patients with cardiac abnormalities
• Potential side effects: bradycardia, dizziness

Motrin

• Generic Name: Ibuprofen
• Nonsteroidal anti-inflammatory drug (NSAID)
• Used to manage mild to moderate pain, rheumatoid arthritis, and osteoarthritis

Lopressor-HCT

• Combination drug containing Metoprolol (beta blocker) and Hydrochlorothiazide (thiazide diuretic)
• Indicated for hypertension
• Usual dosage: 50 to 100 mg of Metoprolol and 25 mg of Hydrochlorothiazide orally daily
• Contraindicated in patients with greater than first-degree heart block or anuria
• Use with caution in patients with cardiac conduction abnormalities, peripheral vascular disease, or sensitivity to thiazide diuretics
• Potential side effects: bradycardia, dizziness, tiredness, electrolyte disturbances, hyponatremia, hypokalemia, photosensitivity

Caduet

• Combination drug containing Atorvastatin (HMG CoA reductase inhibitor) and Amlodipine (calcium channel blocker)
• Indicated for dyslipidemia and hypertension
• Usual starting dosage: 5 mg of Atorvastatin and 10 mg of Amlodipine, dosage can be increased to 10 mg of Atorvastatin and 80 mg of Amlodipine
• Use caution in patients with elevated transaminase enzyme levels
• Potential side effects: muscle pain, gastrointestinal distress, hypotension

Norvasc

• Generic name: Amlodipine
• Calcium channel blocker used to treat hypertension
• Usual dosage: 2.5 to 10 mg orally once daily
• Potential side effects: hypertension, lower extremity edema, headache

Relafen

• Generic name: Nabumetone
• NSAID indicated for mild to moderate pain, rheumatoid arthritis, and osteoarthritis
• Usual dosage: 500 mg to 1000 mg twice daily, maximum daily dose of 2000 mg
• Contraindicated in patients with NSAID hypersensitivity or gastrointestinal ulceration
• Potential side effects: fluid retention (1-3%), photosensitivity (<1%), gastrointestinal diarrhea (<10%)

Practice of Pharmacy

• Pharmacists interpret, evaluate, and dispense prescriptions

Potential Drug Related Problems

• Inaccurate prescriptions
• Drug-drug interactions
• Allergies
• Patient compliance issues

Test your knowledge on common medications like Hydrochlorothiazide, Lopressor, and Motrin. This quiz covers indications, dosages, contraindications, and side effects of these drugs. Perfect for pharmacy students or healthcare professionals.