Pharmacology: Contraindications and Adverse Effects
18 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is a contraindication for the use of macrolide agents?

  • Pregnant women
  • Known allergy to any macrolide
  • Patients with hepatic dysfunction
  • All of the above (correct)

    • What is a possible adverse effect of macrolides on the GI system?

  • Abdominal cramping
  • Diarrhea
  • Hypersensitivity reactions
  • All of the above (correct)

    • Why should caution be used when prescribing macrolides to lactating women?

  • Due to the risk of hypersensitivity reactions
  • Due to the risk of hepatic dysfunction
  • Because of the risk of anorexia
  • Because of drug excretion in breast milk (correct)

    • What is a characteristic of lincosamides compared to macrolides?

    <p>They are more toxic</p> Signup and view all the answers

    What is a drug interaction to be aware of when using lincomycin and clindamycin?

    <p>Incompatibility with both a and b</p> Signup and view all the answers

    What is the mechanism of action of lincosamides?

    <p>Penetrate the cell membrane and bind to the ribosome to prevent protein production</p> Signup and view all the answers

    What is the primary mechanism of action of minocycline in susceptible bacteria?

    <p>Inhibit protein synthesis</p> Signup and view all the answers

    Why is minocycline not recommended for use in children less than 8 years of age?

    <p>Risk of permanent discoloration of the teeth and damage to the bones</p> Signup and view all the answers

    What is a potential consequence of taking tetracyclines with oral contraceptives?

    <p>Decreased effectiveness of the oral contraceptive</p> Signup and view all the answers

    What is a potential consequence of taking tetracyclines with dairy products?

    <p>Decreased absorption of the tetracycline</p> Signup and view all the answers

    What is a potential adverse effect of minocycline on the musculoskeletal system?

    <p>Weakening of the bones and teeth</p> Signup and view all the answers

    What is a potential consequence of taking penicillins with tetracyclines?

    <p>Decreased effectiveness of the penicillin</p> Signup and view all the answers

    What is the reason for contraindicating these agents in patients with known allergy to sulfa drugs, sulfonylureas, and thiazide diuretics?

    <p>The agents have similar structures</p> Signup and view all the answers

    What is the potential effect of these agents on the newborn if taken by lactating women?

    <p>Kernicterus, diarrhea, and rash</p> Signup and view all the answers

    Why is it not recommended to use these agents in pregnancy?

    <p>The agents can cause birth defects and kernicterus</p> Signup and view all the answers

    What is the potential effect of these agents on the bone marrow?

    <p>Bone marrow depression</p> Signup and view all the answers

    What is the primary cause of GI system adverse effects related to these agents?

    <p>Direct irritation of the GIT and death of normal flora</p> Signup and view all the answers

    What is the primary mechanism of CNS adverse effects related to these agents?

    <p>Effects on the nerves</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser