Pharmacology Overview and Drug Standards

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Questions and Answers

Which name is used when a drug is officially recognized by the US FDA?

  • Generic name
  • Brand name
  • Trade name
  • Official name (correct)

What term is used to describe the name a drug manufacturer assigns to its product?

  • Chemical name
  • Official name
  • Nonproprietary name
  • Trademark (correct)

Where does the nonproprietary name of a drug come from?

  • The drug manufacturer
  • The World Health Organization
  • The US Food and Drug Administration (FDA)
  • The United States Adopted Names Council (correct)

In which step of the nursing process is it most important to identify medication errors?

<p>Assessment (D)</p> Signup and view all the answers

Which of the following best describes pharmacokinetics?

<p>The process of how the body affects a drug over time. (C)</p> Signup and view all the answers

What is the primary function of a drug antagonist?

<p>To block a receptor site, preventing a response (B)</p> Signup and view all the answers

Which of the following patient populations requires special consideration for medication administration due to physiological differences?

<p>Pregnant women, pediatric, and elderly patients (D)</p> Signup and view all the answers

During which stage of pregnancy is it essential to have recommendations by the provider regarding drug therapy?

<p>During any stage of pregnancy (A)</p> Signup and view all the answers

What term defines when the drug concentration of a medication reaches a level where the therapeutic effect is observed?

<p>Therapeutic level (C)</p> Signup and view all the answers

Which of the following factors directly influences GI absorption of medications?

<p>Stomach pH (D)</p> Signup and view all the answers

A medication's half-life is 4 hours. After 8 hours, what percentage of the original drug dose remains in the body?

<p>25% (D)</p> Signup and view all the answers

What effect does a higher blood flow to the gastric mucosa typically have on medication absorption?

<p>Increases the absorption of medication and decreases the time of absorption. (C)</p> Signup and view all the answers

A patient's fever is NOT a factor when considering which aspect of pharmacokinetics?

<p>Drug absorption (C)</p> Signup and view all the answers

Besides muscle mass, what other aspect of patient physiology is mentioned to affect medication administration?

<p>Blood flow to muscles (B)</p> Signup and view all the answers

Which of the following is NOT a factor that typically affects drug absorption?

<p>Level of consciousness (C)</p> Signup and view all the answers

Which of the following patient characteristics is LEAST likely to affect medication absorption in general?

<p>Patient weight (C)</p> Signup and view all the answers

A patient with a history of substance abuse has been prescribed several medications. Which of the following options presents the highest potential for abuse, based on the information provided?

<p>Lortab (B)</p> Signup and view all the answers

An elderly patient arrives at the hospital with a weekly pill dispenser and a history of shortness of breath. Neither the patient nor her daughter can provide a list of current medications. Which resource would the nurse find most helpful in determining the medication names and dosages?

<p>Drugs and Facts Comparisons (B)</p> Signup and view all the answers

Which medication schedule category has the lowest risk of abuse?

<p>Schedule V (B)</p> Signup and view all the answers

What is a key difference between Schedule III and Schedule IV drugs in the context of abuse potential?

<p>Schedule III drugs have a higher potential for abuse than Schedule IV drugs. (A)</p> Signup and view all the answers

When assessing a patient's medication history, why is it critical to obtain a comprehensive list of all medications, including prescriptions and over-the-counter drugs?

<p>To identify potential drug interactions and contraindications (B)</p> Signup and view all the answers

A patient is prescribed two different drugs, one from Schedule III and another from Schedule IV. Which statement best describes their comparative risk for abuse?

<p>The Schedule III drug has the higher risk for abuse. (C)</p> Signup and view all the answers

In what context would a nurse refer to Drugs and Facts Comparisons resource?

<p>To rapidly determine a medication name and dosage. (B)</p> Signup and view all the answers

Which factor is most important for a nurse to consider when assessing a patient's medications, pertaining to their risk of abuse?

<p>The medications' schedule classification. (B)</p> Signup and view all the answers

Flashcards

Official drug name

The official name assigned by the US Food and Drug Administration (FDA) to a drug.

Brand name

The name given to a drug by its manufacturer, also known as the trademark.

Generic name

The nonproprietary or generic name for a drug, provided by the United States Adopted Names Council.

United States Pharmacopeia (USP)

A list (published annually) of drugs, drug standards, and therapeutic uses compiled by the United States Pharmacopeial Convention (USP).

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Therapeutic use

The use of a drug in patients with specific conditions, such as cancer or infectious diseases.

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Pharmacology

The study of the effects of drugs on living organisms.

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Drug

A substance that is used to diagnose, treat, or prevent disease.

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Clinical pharmacology

The branch of pharmacology that focuses on the use of drugs in treating disease.

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Pregnancy and Medications

Drug therapy during pregnancy is generally discouraged due to potential risks to the fetus. Healthcare providers should carefully evaluate the need for medication during pregnancy and make informed decisions.

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Pediatric and Elderly Patients

Infants and elderly individuals often experience differences in medication absorption, distribution, metabolism, and excretion due to physiological changes.

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Drug Absorption

The process by which a drug enters the bloodstream from its administration site.

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Stomach pH

The acidity or alkalinity of the stomach environment. It influences how easily a drug dissolves and enters the bloodstream.

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Blood Flow to Gastric Mucosa

The amount of blood flowing to the gastric mucosa (lining of the stomach). Greater blood flow leads to faster drug absorption.

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Level of Consciousness and Absorption

A patient's level of consciousness does not directly impact drug absorption.

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Fever and Absorption

Fever does not directly influence a medication's absorption into the bloodstream.

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Weight and Body Surface Area

The absolute weight and body surface area of a patient do not directly affect drug absorption. However, factors associated with weight extremes (e.g., obesity, malnutrition) might influence other aspects of drug pharmacokinetics.

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Drug Schedules

A classification system used to categorize drugs based on their potential for abuse and dependence. Schedule I drugs have the highest abuse potential and are not approved for medical use in the United States, while Schedule V drugs have the lowest abuse potential.

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Lortab Abuse Potential

Lortab, a Schedule III drug, has a high potential for abuse compared to Schedule IV or V drugs.

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Lomotil Abuse Potential

Lomotil, a Schedule V drug, has a lower potential for abuse compared to Schedule III drugs.

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Diazepam Abuse Potential

Diazepam, a Schedule IV drug, has a lower potential for abuse compared to Schedule III drugs.

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Phenobarbital Abuse Potential

Phenobarbital, a Schedule IV drug, has a lower potential for abuse compared to Schedule III drugs.

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What is Martindale—The Complete Drug Reference?

A comprehensive reference book for medications that includes information on their properties, uses, interactions, and adverse effects.

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What is Drugs and Facts Comparisons?

A comprehensive reference book that provides detailed information about drugs, including their chemical properties, uses, and interactions.

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What is a Substance of Abuse?

A drug that can be abused and lead to dependence.

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Study Notes

Drug Definitions and Standards

  • Official drug names are listed by the FDA
  • Brand names are given by manufacturers
  • Generic names are given by the United States Adopted Names Council

Drug Abuse Potential

  • Lortab (Schedule III) has a high potential for abuse, but less than Schedule I or II drugs
  • Lomotil (Schedule V) has low potential for abuse
  • Diazepam (Schedule IV) has low potential for abuse
  • Phenobarbital (Schedule IV) has low potential for abuse

Medication History and Resources

  • If a patient and their caregiver don't have a list of medications, use resources like Martindale—The Complete Drug Reference or Drugs and Facts Comparisons to identify medication names and dosages

Drug Therapy During Pregnancy

  • Avoid drug therapy during pregnancy unless provider recommendations are given
  • Consider physiological differences in elderly and pediatric patients when administering medication.

Factors Influencing GI Absorption

  • Stomach pH - Affects passive diffusion absorption
  • Blood flow to gastric mucosa- Affects absorption rate
  • Level of consciousness - Does not influence absorption
  • Fever - Does not influence absorption
  • Weight/Body surface area - Does not directly affect absorption, but patient's size-related health issues may influence the process.

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