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Questions and Answers
Following drugs directly activate the respiratory center EXCEPT:
The mechanism of Cytiton action is:
Indicate the drug belonging to antitussives of narcotic type of action:
Tick out the drug belonging to non-narcotic antitussives:
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Indicate the expectorant with the reflex mechanism:
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Tick the antitussive agent with a peripheral effect:
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Chymotrypsin is an agent containing free sulfhydryl groups.
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All of these drugs contain free sulfhydryl groups EXCEPT:
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Which of the following drugs is a proteolytic enzyme?
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All of the following drugs destroy disulfide bonds of proteoglycans, which causes depolymerization and reduction of viscosity of sputum, EXCEPT:
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Which of these groups of drugs is used for asthma treatment?
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Tick the drug belonging to non-selective beta2-adrenomimics:
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Select the side-effect characteristic for non-selective beta2-adrenomimics:
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Pick out the bronchodilator drug related to xanthine:
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Pick out the bronchodilator drug belonging to symptomatic:
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The property of prolonged theophylline’s is the prevention of night asthmatic attacks.
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The mechanism of methylxanthines action is:
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Which of the following M-cholinoblocking agents is used especially as an anti-asthmatic?
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Indicate the side effect of Theophylline:
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All of the following drugs are inhaled glucocorticoids EXCEPT:
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Choose the drug belonging to membrane stabilizing agents:
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Tick the drug which is a 5-lipoxygenase inhibitor:
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Zileuton prevents the production of leukotrienes.
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Indicate the drug which is a leukotriene receptor antagonist:
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Zafirlukast prevents aspirin-sensitive asthma.
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Study Notes
Respiratory Stimulants
- Bemegride, Caffeine, and Aethymizole directly activate the respiratory center.
- Cytiton works through a mixed mechanism, not direct activation of the respiratory center.
Antitussives
- Methylmorphine Hydrochloride is a narcotic antitussive.
- Libexine, Tusuprex, and Glaucine Hydrochloride are non-narcotic antitussives.
Expectorants
- Derivatives of Ipecacuanha and Thermopsis work through a reflex mechanism.
- Sodium Benzoate, Trypsin, and Ambroxol are expectorants.
Antitussives with Peripheral Effects
- Tusuprex, Libexine, and Glaucine Hydrochloride have peripheral effects.
Sulfhydryl Groups
- Chymotrypsin does contain free sulfhydryl groups.
- Acetylcysteine, Ambroxol, Bromhexine, and Trypsin all contain free sulfhydryl groups.
- Acetylcysteine and Bromhexine are the exceptions to this statement, they do not contain free sulfhydryl groups.
Proteolytic Enzymes
- Deoxyribonuclease and Trypsin are proteolytic enzymes.
Sputum Viscosity
- Acetylcysteine, Ambroxol, Deoxyribonuclease, and Bromhexine all destroy disulfide bonds of proteoglycans to depolymerize and reduce the viscosity of sputum.
Asthma Treatment
- Methylxanthines, M-cholinoblocking agents, and Beta2-stimulants are all used in asthma treatment.
Beta2-Adrenomimics
- Isoprenaline is a non-selective beta2-adrenomimics.
- Salbutamol, Salmeterol, and Terbutaline are selective beta2-adrenomimics.
Side effects of Non-selective Beta2-Adrenomimics
- Tachycardia, Peripheral vasoconstriction, and dry mouth are side effects associated with non-selective beta2-adrenomimics.
Xanthine Bronchodilators
- Theophylline is a bronchodilator related to Xanthines.
Symptomatic Bronchodilators
- Isoprenaline, Ephedrine, and Salbutamol are symptomatic bronchodilators.
- Atropine is not a symptomatic bronchodilator.
Theophylline Properties
- Theophylline can prevent night asthmatic attacks.
Methylxanthines Mechanisms
- Methylxanthines work by inhibiting phosphodiesterase, stimulating beta2-adrenoreceptors, and inhibiting the production of inflammatory cytokines.
M-Cholinoblocking Agents
- Ipratropium is a M-Cholinoblocking agent used for asthma.
Theophylline Side Effects
- Increased myocardial demands for oxygen is a side effect associated with Theophylline.
Inhaled Glucocorticoids
- Triamcinolone, Beclomethasone, and Budesonide are inhaled glucocorticoids.
- Sodium Cromoglycate is not an inhaled glucocorticoid.
Membrane Stabilizing Agents
- Sodium Cromoglycate, Zafirlukast, and Montelukast are membrane stabilizing agents.
5- Lipoxygenase Inhibitors
- Zileuton is a 5-lipoxygenase inhibitor.
Zileuton Prevention
- Zileuton does prevent the production of leukotrienes.
Leukotriene Receptor Antagonists
- Zafirlukast is a leukotriene receptor antagonist.
Zafirlukast and Aspirin Sensitive Asthma
- Zafirlukast may prevent aspirin-sensitive asthma.
COPD Treatment
- Albuterol is a bronchodilator that would be most appropriate for initial treatment of COPD.
Acute Asthma Exacerbation
- Epinephrine is administered first to provide rapid relief of symptoms in an acute asthma exacerbation.
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Description
This quiz covers important concepts related to respiratory stimulants, antitussives, and expectorants, including their mechanisms of action and specific examples of each class. Test your knowledge on the role of various medications like Bemegride, Methylmorphine Hydrochloride, and Chymotrypsin. Additionally, explore the classification of these pharmacological agents.
