MCQS Course 2 (4th Semester) PDF

THEME 1 1. Following drugs directly activate the respiratory center EXCEPT: A. Bemegride B. Caffeine C. Aethymizole D. Cytiton 2. The mechanism of Cytiton action is: A. Direct activation of the respiratory center B. The reflex mechanism C. The mixed mechanism...

THEME 1 1. Following drugs directly activate the respiratory center EXCEPT: A. Bemegride B. Caffeine C. Aethymizole D. Cytiton 2. The mechanism of Cytiton action is: A. Direct activation of the respiratory center B. The reflex mechanism C. The mixed mechanism D. None of the above 3. Indicate the drug belonging to antitussives of narcotic type of action: A. Glaucine hydrochloride B. Methylmorphine hydrochloride C. Tusuprex D. Libexine 4. Tick out the drug belonging to non-narcotic antitussives: A. Libexine B. Tusuprex C. Codeine D. Methylmorphine hydrochloride 5. Indicate the expectorant with the reflex mechanism: A. Sodium benzoate B. Derivatives of Ipecacuanha and Thermopsis C. Trypsin D. Ambroxol 6. Tick the antitussive agent with a peripheral effect: A. Codeine B. Tusuprex C. Libexine D. Glaucine hydrochloride 7. Chymotrypsin is an agent containing free sulfhydryl groups. It’s: A. True B. False C. Ambroxol D. Bromhexine 8. All of these drugs contain free sulfhydryl groups EXCEPT: A. Acetylcysteine B. Ambroxol C. Bromhexine D. Trypsin 9. Which of the following drugs is proteolytic enzyme? A. Potassium iodide B. Deoxyribonuclease C. Carbocysteine D. Acetylcysteine 10. All of the following drugs destroy disulfide bonds of proteoglycans, which causes depolymerization and reduction of viscosity of sputum, EXCEPT: A. Acetylcysteine B. Ambroxol C. Deoxyribonuclease D. Bromhexine 11. Which of these groups of drugs is used for asthma treatment? A. Methylxanthines B. M-cholinoblocking agents C. Beta2 - stimulants D. All of above 12. Tick the drug belonging to non-selective beta2-adrenomimics: A. Salbutamol B. Isoprenaline C. Salmeterol D. Terbutaline 13. Select the side-effect characteristic for non-selective beta2-adrenomimics: A. Depression of the breathing center B. Tachycardia C. Peripheral vasoconstriction D. Dry mouth 14. Pick out the bronchodilator drug related to xanthine: A. Atropine B. Orciprenaline C. Adrenaline D. Theophylline 15. Pick out the bronchodilator drug belonging to symptomatic: A. Isoprenaline B. Ephedrine C. Atropine D. Salbutamol 16. The property of prolonged theophylline’s is the prevention of night asthmatic attacks. It’s: A. True B. False C. Ambroxol D. Bromhexine 17. The mechanism of methylxanthines action is: A. Inhibition of the enzyme phosphodiesterase B. Beta2 -adrenoreceptor stimulation C. Inhibition of the production of inflammatory cytokines D. Inhibition of M- cholinoreceptors 18. Which of the following M-cholinoblocking agents is used especially as an anti- asthmatic? A. Atropine B. Ipratropium C. Platyphylline D. Mattacin 19. Indicate the side effect of Theophylline: A. Bradycardia B. Increased myocardial demands for oxygen. C. Depression of respiratory center D. Elevation of the arterial blood pressure 20. All of the following drugs are inhaled glucocorticoids EXCEPT: A. Triamcinolone B. Beclomethasone C. Sodium cromoglycate D. Budesonide 21. Choose the drug belonging to membrane stabilizing agents: A. Zileuton B. Sodium cromoglycate C. Zafirlukast D. Montelukast 22. Tick the drug which is a 5-lipoxygenase inhibitor: A. Budesonide B. Sodium cromoglycate C. Zileuton D. Beclomethasone 23. Zileuton prevents the production of leukotrienes. This statement is: A. True B. False C. Zileuton D. Triamcinolone 24. Indicate the drug which is a leukotriene receptor antagonist: A. Sodium cromoglycate B. Zafirlukast C. Zileuton D. Triamcinolone 25. Zafirlukast prevents aspirin-sensitive asthma. This consideration is: A. True B. False C. Zileuton D. Triamcinolone 26. Select the side-effect characteristic for non-selective beta2-adrenomimics: A. Depression of the breathing center B. Tachycardia C. Peripheral vasoconstriction D. Dry mouth 27. Pick out the bronchodilator drug related to xanthine: A. Atropine B. Orciprenaline C. Adrenaline D. Theophylline 28. Pick out the bronchodilator drug belonging to symptomatic: 1. Isoprenaline 2. Ephedrine 3. Atropine 4. Salbutamol 29. Choose the drug belonging to membrane stabilizing agents: 1. Zileuton 2. Sodium cromoglycate 3. Zafirlukast 4. Montelukast 30. Tick the drug which is a 5-lipoxygenase inhibitor: 1. Budesonide 2. Sodium cromoglycate 3. Zileuton 4. Beclomethasone 31. A 65-year-old male with a history of chronic obstructive pulmonary disease (COPD) presents with worsening dyspnea and wheezing. Which of the following bronchodilators would be most appropriate for initial treatment? A. Albuterol B. Ipratropium C. Salmeterol D. Montelukast 32. A 45-year-old female with a history of asthma presents with acute exacerbation characterized by severe dyspnea and wheezing. What medication should be administered first for rapid relief of symptoms? A. Beclomethasone B. Theophylline C. Epinephrine D. Cromolyn 33. A 55-year-old male with a history of COPD and chronic bronchitis presents with a persistent cough and excessive mucus production. Which of the following medications would be most appropriate to reduce mucus secretion? A. Albuterol B. Ipratropium C. Guaifenesin D. Montelukast 34. A 40-year-old male presents with allergic rhinitis characterized by nasal congestion, sneezing, and itching. Which of the following medications is a leukotriene receptor antagonist commonly used for the treatment of allergic rhinitis? { A. Fluticasone  B. Montelukast C. Cetirizine D. Oxymetazoline 35. A 30-year-old female with a history of seasonal allergies presents with symptoms of allergic rhinitis. Which of the following medications is a second-generation antihistamine that can effectively relieve her symptoms without causing sedation? a. Diphenhydramine B. Loratadine C. Chlorpheniramine D. Promethazine THEME 2 36. All of the following are normally involved in the pathogenesis of heart failure EXCEPT: A cardiac lesion that impairs cardiac output An increase in peripheral vascular resistance A decrease in preload An increase in sodium and water retention 37. All of the following are compensatory mechanisms that occur during the pathogenesis of congestive heart failure EXCEPT: A. An increase in ventricular end-diastolic volume B. An increase in the concentration of plasma catecholamines C. An increase in vagal tone D. Increased activity of the renin-angiotensin-aldosterone system 38. All of the following are recommended at the initial stages of treating patients with heart failure EXCEPT: A. Reduced salt intake B. Verapamil C. ACE inhibitors D. Diuretics 39. All of the following agents belong to cardiac glycosides EXCEPT: A. Digoxin B. Strophantin K C. Amrinone D. Digitoxin 40. The non-glycoside positive inotropic drug is: A. Digoxin B. Strophantin K C. Dobutamine D. Digitoxin 41. Sugar molecules in the structure of glycosides influence: A. Cardiotonic action B. Pharmacokinetic properties C. Toxic properties D. All of the above 42. Aglycone is essential for: A. Plasma protein binding B. Half-life C. Cardiotonic action D. Metabolism 43. Choose the derivative of the plant Foxglove (Digitalis): A. Digoxin B. Strophantin K C. Dobutamine D. Amrinon 44. All of the following statements regarding cardiac glycosides are true EXCEPT: A. They inhibit the Na+/K+-ATPase and thereby increase intracellular Ca++ in myocardial cells. B. They cause a decrease in vagal tone. C. Children tolerate higher doses of digitalis than do adults. D. The most frequent cause of digitalis intoxication is concurrent administration of diuretics that deplete K+ 45. All of the following statements regarding cardiac glycosides are true EXCEPT: A. They inhibit the activity of the Na+/K+-ATPase. B. They decrease intracellular concentrations of calcium in myocytes. C. They increase vagal tone. D. They have a very low therapeutic index. 46. All of the following statements regarding cardiac glycosides are true EXCEPT: A. Digoxin is a mild inotrope. B. Digoxin increases vagal tone. C. Digoxin has a longer half-life than digitoxin. D. Digoxin acts by inhibiting the Na+/K+ ATPase. 47. The most cardiac manifestation of glycosides intoxication is: A. Atrioventricular junctional rhythm B. Second-degree atrioventricular blockade C. Ventricular tachycardia D. All the above 48. The manifestations of glycosides intoxication are: A. Visual changes B. Ventricular tachyarrhythmias C. Gastrointestinal disturbances D. All the above 49. For digitalis-induced arrhythmias the following drug is favored: A. Verapamil B. Amiodarone C. Lidocaine D. Propranolol 50. In very severe digitalis intoxication, the best choice is to use: A. Lidocaine B. Digibind (Digoxin immune fab) C. Oral potassium supplementation D. Reducing the dose of the drug 51. All of the following statements regarding cardiac glycoside-induced ventricular tachyarrhythmias are true ECEPT: A. Lidocaine is a drug of choice in treatment. B. Digibind should be used in life-threatening cases. C. They occur more frequently in patients with hyperkalemia than in those with hypokalemia. D. ~They are more likely to occur in patients with a severely damaged heart. 52. This drug is a selective beta-1 agonist: A. Digoxin B. Dobutamine C. Amrinone D. Dopamine 53. Tolerance to this inotropic drug develops after a few days: A. Amrinone B. Amiodarone C. Dobutamine D. Adenosine 54. This drug inhibits breakdown of cAMP in vascular smooth muscle: A. Digoxin B. Dobutamine C. Amrinone D. Dopamine 55. This drug is useful for treating heart failure because it increases the inotropic state and reduces afterload: A. Amiodarone B. Amrinone C. Propranolol D. Enalapril 56. This drug acts by inhibiting type III cyclic nucleotide phosphodiesterase: A. Amiodarone B. Milrinone C. Propranolol D. Enalapril 57. All of the following statements regarding inhibitors of type III phosphodiesterase are true EXCEPT: A. They raise cAMP concentrations in cardiac myocytes. B. They reduce afterload. C. They show significant cross-tolerance with beta-receptor agonists. D. They are associated with a significant risk for cardiac arrhythmias. 58. All of the following drugs are used in the treatment of severe congestive heart failure EXCEPT: A. Verapamil B. Digoxin C. Dobutamine D. Dopamine 59. Drugs most commonly used in chronic heart failure are: A. Cardiac glycosides B. Diuretics C. Angiotensin-converting enzyme inhibitors D. All the above 60. All of the following statements concerning angiotensin converting enzyme (ACE) inhibitors are true EXCEPT: A. They act by inhibiting the ability of renin to convert angiotensinogen to angiotensin I. B. Enalapril is a prodrug that is converted to an active metabolite. C. They reduce secretion of aldosterone. D. They can produce hyperkalemia in combination with a potassium-sparing diuretic. 61. All of the following effects of ACE inhibitors may be useful in treating heart failure EXCEPT: A. They decrease afterload. B. They increase circulating catecholamine levels. C. They reduce reactive myocardial hypertrophy. D. They increase myocardial beta-1 adrenergic receptor density. 62. All of the following statements concerning the use of angiotensin-converting enzyme (ACE) inhibitors in the treatment of heart failure are true EXCEPT: A. They improve hemodynamics by decreasing afterload. B. They can increase plasma cholesterol levels C. They may slow the progression of heart failure by preventing myocardial and vascular remodeling. D. They are effective first-line agents in the treatment of chronic heart failure. 63. This drug inhibits breakdown of cAMP in vascular smooth muscle: A. Digoxin B. Dobutamine C. Amrinone D. Dopamine 64. Sugar molecules in the structure of glycosides influence: A. Cardiotonic action B. Pharmacokinetic properties C. Toxic properties D. All of the above 65. Aglycone is essential for: A. Plasma protein binding B. Half-life C. Cardiotonic action D. Metabolism