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Pharmacology of analgesic drugs
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Pharmacology of analgesic drugs

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@DelightfulPink

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Questions and Answers

Which enzyme is targeted by NSAIDs?

  • Cyclo-oxygenase (correct)
  • Platelets
  • Prostaglandins
  • Nociceptors

    • Which of the following is a common small animal NSAID?

  • Flunixin meglumine
  • Meloxicam (correct)
  • Ketoprofen
  • Phenylbutazone

    • Which organ is protected by prostaglandins?

  • Stomach (correct)
  • Liver
  • Kidneys
  • Heart

    • Which pathways are targeted by NSAIDs?

    <p>Descending pain pathways</p> Signup and view all the answers

    Which NSAID should not be given if the animal is part of the food chain?

    <p>Phenylbutazone</p> Signup and view all the answers

    Which of the following is a common equine NSAID?

    <p>Flunixin meglumine</p> Signup and view all the answers

    In which species should NSAIDs be used for castration, disbudding, assisting calving, and foot care?

    <p>Cattle</p> Signup and view all the answers

    In which patients are NSAIDs contraindicated?

    <p>All of the above</p> Signup and view all the answers

    Which side effects should be monitored in animals receiving NSAIDs for any period of time?

    <p>Gastrointestinal problems</p> Signup and view all the answers

    Which enzyme stimulates the production of prostaglandins?

    <p>Cyclo-oxygenase</p> Signup and view all the answers

    Which class of drugs directly acts upon the EP4 receptor to prevent prostaglandin effects?

    <p>Grapiprant/galliprant</p> Signup and view all the answers

    Which drug can be used intravenously in dogs and horses, but should never be used in cats?

    <p>Paracetamol</p> Signup and view all the answers

    Which receptor does morphine primarily act on?

    <p>Mu</p> Signup and view all the answers

    Which type of local anaesthetics are hydrolysed by plasma cholinesterases?

    <p>Esters</p> Signup and view all the answers

    Which route of administration can be used for ketamine?

    <p>Intramuscular</p> Signup and view all the answers

    Which drug class can produce a state of sedation or euphoria?

    <p>Opioids</p> Signup and view all the answers

    Which receptor do alpha 2 agonists interact with to produce their effects?

    <p>Alpha-2</p> Signup and view all the answers

    What is the aim of Grapiprant/galliprant?

    <p>Targets canine osteoarthritis pain and inflammation</p> Signup and view all the answers

    What is the main use of Lidocaine spray in veterinary medicine?

    <p>Intubation</p> Signup and view all the answers

    What is the main use of Emmla cream in veterinary medicine?

    <p>Skin numbing</p> Signup and view all the answers

    Which enzyme is activated after the body is damaged and stimulates the production of prostaglandins?

    <p>Cox enzymes</p> Signup and view all the answers

    Which of the following signs are caused by prostaglandins?

    <p>Inflammation</p> Signup and view all the answers

    Which receptor do opioids act on to produce their effects?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a characteristic of local anaesthetics?

    <p>They exist in equilibrium between ionized and unionized forms</p> Signup and view all the answers

    Which organ is protected by prostaglandins?

    <p>Stomach and intestines</p> Signup and view all the answers

    Which class of drugs directly acts upon the EP4 receptor to prevent prostaglandin effects?

    <p>Galliprant/gapiprant</p> Signup and view all the answers

    Which of the following is a common small animal NSAID?

    <p>Meloxicam</p> Signup and view all the answers

    Which of the following is a use of Emmla cream in veterinary medicine?

    <p>Skin numbing</p> Signup and view all the answers

    Which of the following is a common equine NSAID?

    <p>Phenylbutazone</p> Signup and view all the answers

    Which route of administration can be used for ketamine?

    <p>Both intravenous and intramuscular</p> Signup and view all the answers

    Which of the following is a use of Grapiprant/galliprant in veterinary medicine?

    <p>Pain and inflammation in osteoarthritis</p> Signup and view all the answers

    Which side effects should be monitored in animals receiving NSAIDs for any period of time?

    <p>All of the above</p> Signup and view all the answers

    Which enzyme targets the production of prostaglandins?

    <p>Cyclooxygenase</p> Signup and view all the answers

    Which type of local anaesthetics arre hydrolysed by the liver?

    <p>Amides</p> Signup and view all the answers

    In which patients are NSAIDs contraindicated?

    <p>All of the above</p> Signup and view all the answers

    Which drug can be used intravenously in dogs and horses, but should never be used in cats?

    <p>Paracetamol</p> Signup and view all the answers

    Which enzyme is targeted by NSAIDs?

    <p>Cyclo-oxygenase</p> Signup and view all the answers

    Which organ is protected by prostaglandins?

    <p>Stomach and intestines</p> Signup and view all the answers

    Which drug class can produce a state of sedation or euphoria?

    <p>Opioids</p> Signup and view all the answers

    In which species should NSAIDs be used for castration, disbudding, assisting carving, and foot care?

    <p>Cattle and small ruminants</p> Signup and view all the answers

    Which side effects should be monitored in animals receiving NSAIDs for any period of time?

    <p>Renal, hepatic, and clotting problems</p> Signup and view all the answers

    Which receptor does Galliprant directly act upon to prevent prostaglandin effects?

    <p>EP4 receptor</p> Signup and view all the answers

    Which of the following is a characteristic of opioids?

    <p>They can produce a state of sedation or euphoria</p> Signup and view all the answers

    Which of the following is a use of local anaesthetics in veterinary medicine?

    <p>Analgesia for the whole area of a limb</p> Signup and view all the answers

    Which enzyme is targeted by NSAIDs?

    <p>Cyclo-oxygenase</p> Signup and view all the answers

    Which of the following is a use of ketamine in veterinary medicine?

    <p>Induction agent for anesthesia</p> Signup and view all the answers

    Which receptor do alpha 2 agonists interact with to produce their effects?

    <p>Alpha-2 receptor</p> Signup and view all the answers

    What is one of the effects of alpha 2 agonists?

    <p>Analgesia</p> Signup and view all the answers

    What is the antagonist for alpha 2 agonists?

    <p>Atipamezole</p> Signup and view all the answers

    What is the main use of ketamine in veterinary medicine?

    <p>Induction agent</p> Signup and view all the answers

    How does ketamine produce its analgesic effect?

    <p>By acting on the NMDA receptor</p> Signup and view all the answers

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