10 Questions
Which type of nerve fibers are most affected by local anaesthetics?
Smaller neuronal alpha-delta fibres
What is the elimination half-life of lignocaine in the liver?
2 hours
What is the primary mechanism of cardiovascular toxicity caused by lignocaine?
Blockage of sodium channels
What is the primary cause of true allergy to local anaesthetics?
Type I IgE-mediated immunological reaction
What is the common symptom of an allergic reaction to ester-type local anaesthetics?
Generalised urticaria and pruritus
What is the reason for avoiding octapressin in pregnancy?
It can induce labour
What is the common cause of autonomic response to an injection in patients undergoing dental procedures?
Anxiety or adrenaline injection
What is the first modality to disappear during local anaesthesia?
Pain
What is the primary factor that determines the plasma concentration of local anaesthetics?
All of the above
What is the common complication of local anaesthesia at therapeutic plasma concentrations?
Tachycardia
This quiz covers the pharmacology of local anaesthesia, including pain management, action potential and pain pathways, chemical composition, and mechanisms of action of local anaesthetics.
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