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Questions and Answers
What is the function of Sofosbuvir in inhibiting HCV?
What is the function of Sofosbuvir in inhibiting HCV?
- It activates the HCV NS5B RNA-dependent RNA polymerase
- It inhibits the HCV NS5B RNA-dependent RNA polymerase (correct)
- It eliminates the HCV from the urine
- It inhibits the host cell kinases
What is Sofosbuvir classified as?
What is Sofosbuvir classified as?
- Nucleotide analog (correct)
- NS5A inhibitor
- Protease inhibitor
- HCV NS3/4A inhibitor
How is Sofosbuvir activated?
How is Sofosbuvir activated?
- By HCV RNA-dependent RNA polymerase
- By ribavirin
- By host cell kinases (correct)
- By peginterferon alfa
What is the route of elimination of Sofosbuvir?
What is the route of elimination of Sofosbuvir?
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What is the recommended combination therapy for Sofosbuvir?
What is the recommended combination therapy for Sofosbuvir?
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Study Notes
NS5B Polymerase Inhibitors
- Sofosbuvir is an NS5B polymerase inhibitor.
- Sofosbuvir is a nucleotide analog.
- It inhibits HCV NS5B RNA-dependent RNA polymerase.
- The drug is activated by host cell kinases to its triphosphate form.
- Sofosbuvir is administered with ribavirin and peginterferon alfa.
- It can be taken with or without food.
- The drug is eliminated in the urine.
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Description
This quiz covers the characteristics and functions of NS5B polymerase inhibitors, specifically Sofosbuvir, including its mechanism of action, administration, and elimination. Learn about the treatment of HCV and its related compounds.Brush up on your pharmacology knowledge and take this quiz!
