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Questions and Answers
What is the mechanism of action for Interferons?
Antiviral agents can cause bone marrow suppression as an adverse effect.
False
Name one drug exemplar for protease inhibitors used in Hepatitis C treatment.
Boceprevir
Interferons are primarily used to treat __________ B and C.
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Match the therapeutic uses with the corresponding drug exemplars:
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Which of the following is NOT a common adverse effect of antiviral drugs?
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Supplements are primarily used to treat viral infections.
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What type of medications are Protease Inhibitors classified as?
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Study Notes
Immune Stimulants
- Interferons are proteins that modify the immune response, stimulating interferon receptor sites to produce antiviral proteins which prevent viruses from entering cells.
- Interferons are used to treat Hepatitis B and C.
- Common side effects include flu-like symptoms, bone marrow suppression, cardiotoxicity, dyspnea, alopecia, and GI upset.
- Monitor CBC levels, cardiac and liver function throughout therapy.
Antiviral Agents
- Protease inhibitors block protease activity to render HIV particles unable to fuse with and inject themselves into a cell.
- Protease inhibitors are used to treat Hepatitis C.
- Protease inhibitors can cause various gastrointestinal effects, changes in liver function, elevated cholesterol and triglyceride levels, fat redistribution, and Stevens-Johnson syndrome.
- Antiviral drugs inhibit viral DNA replication by competing with viral substrates to form shorter, ineffective DNA chains.
- Antiviral drugs are used to treat Hepatitis C.
- Common side effects include nausea, vomiting, headache, depression, paresthesia, neuropathy, rash, hair loss, and renal dysfunction.
Supplements
- Thiamine is a vitamin that replaces deficiencies and is required for carbohydrate metabolism.
- Thiamine is used to treat deficiencies.
- Thiamine has extremely minimal reactions or side effects.
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Description
Test your knowledge on immune stimulants and antiviral agents. This quiz covers the roles of interferons, protease inhibitors, and their side effects. Additionally, review the mechanisms of antiviral drugs and their clinical applications in treating viral infections.
