Chronic Hepatitis B & C Treatment Recommendations
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Questions and Answers

Under what conditions should antiviral therapy be initiated in chronic hepatitis B patients?

  • Patients with undetectable HBV DNA levels
  • HBeAg-positive with persistently elevated ALT (correct)
  • Patients with normal liver histology
  • HBeAg-negative with normal ALT levels

    • What is the desired outcome of chronic hepatitis B treatment?

  • Decrease in HBsAg concentration
  • Loss of HBeAg
  • Prevention of disease progression to cirrhosis and HCC (correct)
  • Suppression of HCV replication

    • How is response to antiviral therapy monitored in chronic hepatitis B patients?

  • Increase in HBeAg levels
  • Increase in histologic activity by at least 2 points
  • Reduction of HBV DNA to undetectable concentrations (correct)
  • Normalization of AST levels

    • What is considered a primary nonresponse to antiviral therapy in chronic hepatitis B?

    <p>Decrease in HBV DNA by at least 2 log/mL after 24 weeks</p> Signup and view all the answers

    According to AASLD guidelines, which patients are recommended for antiviral therapy for chronic hepatitis B?

    <p>Adults with immune active CHB to decrease the risk of liver-related complications</p> Signup and view all the answers

    Which of the following is NOT a component of the hepatobiliary system?

    <p>Pancreas</p> Signup and view all the answers

    What is the approximate weight of the liver in an average adult?

    <p>1400-1600 g</p> Signup and view all the answers

    Where does venous blood from the intestine flow before it is returned to the heart?

    <p>Liver</p> Signup and view all the answers

    What is the main function of Kupffer’s cells in the liver?

    <p>Foreign matter removal</p> Signup and view all the answers

    Where is the liver located in relation to the gastrointestinal tract and the systemic circulation?

    <p>Between the gastrointestinal tract and the systemic circulation</p> Signup and view all the answers

    Viral hepatitis can only be transmitted through blood contact and cannot be spread through other means

    <p>False</p> Signup and view all the answers

    The liver is the second largest organ in the body

    <p>False</p> Signup and view all the answers

    Kupffer's cells are responsible for removing nutrients during portal circulation

    <p>False</p> Signup and view all the answers

    Antiviral therapy is not recommended for chronic hepatitis B patients with high viral loads

    <p>False</p> Signup and view all the answers

    The hepatobiliary system includes the liver, gallbladder, and pancreas

    <p>False</p> Signup and view all the answers

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