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Pharmacology: Norepinephrine Actions Quiz

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Pharmacology: Norepinephrine Actions Quiz

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Questions and Answers

What is the primary therapeutic use of norepinephrine?

To act as a potent bronchodilator
To stimulate the heart, increasing heart rate, contractility, and cardiac output
To treat shock by increasing vascular resistance and blood pressure (correct)
To dilate the arterioles of skeletal muscle

How does the reflex compensation caused by atropine affect the action of norepinephrine on the heart?

It enhances the positive inotropic effects of norepinephrine
It blocks the transmission of vagal effects, allowing the stimulatory effects of norepinephrine to be observed (correct)
It has no effect on the action of norepinephrine on the heart
It is sufficient to counteract the local actions of norepinephrine on the heart

What is the primary drawback of isoproterenol?

Its ability to dilate the arterioles of skeletal muscle
Its weak stimulation of $\alpha$ receptors
Its potent bronchodilator effect
Its non-selectivity for $\beta_1$- and $\beta_2$-adrenergic receptors (correct)

How does dopamine's action on different receptors affect its cardiovascular effects?

Dopamine activates $\alpha_1$ receptors on the vasculature, resulting in vasoconstriction at higher doses (C) Signup and view all the answers

Where are the D1 and D2 dopaminergic receptors found, and what is their effect?

D1 and D2 receptors are found in the peripheral mesenteric and renal vascular beds, where they produce vasodilation (B) Signup and view all the answers

What is the primary effect of norepinephrine on the cardiovascular system?

Vasoconstriction of most vascular beds (C) Signup and view all the answers

Which of the following statements about norepinephrine is correct?

It causes a reflex bradycardia due to increased blood pressure (D) Signup and view all the answers

Why is norepinephrine not useful in the treatment of asthma or anaphylaxis?

It has weak $\beta_2$ activity (A) Signup and view all the answers

Which of the following effects is NOT observed with norepinephrine administration?

Decreased heart rate (B) Signup and view all the answers

How does the vasoconstriction effect of norepinephrine compare to that of epinephrine?

Norepinephrine causes more vasoconstriction than epinephrine (B) Signup and view all the answers