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Pharmacology Multiple Choice Questions

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Questions and Answers

Which of the following is a Phase 1 reaction?

Sulfate Conjugation

Hydrolysis (correct)

Acetylation

Methylation

Which enzyme inducer is associated with chronic alcoholism?

Phenobarbital (correct)

Erythromycin

Metronidazole

Cimetidine

What is the main purpose of biotransformation of a drug?

To convert it into an inactive metabolite or a more soluble compound (correct)

To increase its toxicity

To decrease its solubility

To enhance its pharmacological activity

What is the major pathway for sulfate conjugation in drug metabolism?

Phenols Signup and view all the answers

What does the volume of distribution (Vd) signify?

The volume of fluid required to contain the total amount of drug in the body at the same concentration as that present in the plasma Signup and view all the answers

What is the major pathway for sulfate conjugation?

Phenols Signup and view all the answers

What is the volume of distribution (Vd)?

The volume of fluid required to contain the total amount of drug in the body at the same concentration as that present in the plasma Signup and view all the answers

Which of these compounds is primarily metabolized through sulfate conjugation?

Acetaminophen Signup and view all the answers

In the context of drug metabolism, what is methylation?

A Phase 2 reaction that adds a methyl group to a drug Signup and view all the answers

Which option describes a characteristic of drugs with a high volume of distribution?

They accumulate significantly in body tissues. Signup and view all the answers

Study Notes

Multiple Choice Questions - Pharmacology

Sulfate Conjugation Pathway: The major pathway for sulfate conjugation is phenols.
Volume of Distribution (Vd): Vd is the volume of fluid needed to contain the total amount of a drug in the body at the same concentration as in the plasma.
Phase 1 Reaction: One example of a Phase 1 reaction is hydrolysis.
Chronic Alcoholism Enzyme Inducer: Phenobarbital is an enzyme inducer associated with chronic alcoholism.
Drug Biotransformation Purpose: Biotransformation converts a drug into an inactive metabolite or a more soluble compound to enhance its pharmacological activity.

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Description

Test your knowledge on key concepts in pharmacology with this multiple choice questions quiz. Topics include sulfate conjugation pathways, volume of distribution, and the effects of chronic alcoholism on enzyme induction. Perfect for students studying pharmacology in their courses.