5 Questions
Which organ is the most important for biotransformation of drugs?
Liver
What is the primary purpose of biotransformation in the body?
To convert drugs into more polar, water-soluble compounds for easier excretion through the kidneys
Which drug is an example of being largely excreted unchanged in the urine?
Furosemide
What is the consequence of biotransformation for some drugs?
Inactivation
Where are biotransformation reactions catalyzed by enzymes located?
Both in the liver microsomes and cytoplasm/mitochondria
Test your knowledge on the process of drug biotransformation, which involves the biochemical alteration of drugs in the body to make them more water-soluble for excretion. Explore the site of metabolism and its consequences.
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