Podcast
Questions and Answers
Which organ is the most important for biotransformation of drugs?
Which organ is the most important for biotransformation of drugs?
- Lungs
- Gut mucosa
- Kidney
- Liver (correct)
What is the primary purpose of biotransformation in the body?
What is the primary purpose of biotransformation in the body?
- To convert drugs into more polar, water-soluble compounds for easier excretion through the kidneys (correct)
- To decrease excretion through the kidneys
- To make drugs more lipid-soluble
- To activate inactive drugs
Which drug is an example of being largely excreted unchanged in the urine?
Which drug is an example of being largely excreted unchanged in the urine?
- Furosemide (correct)
- Paracetamol
- Enrofloxacin
- Ciprofloxacin
What is the consequence of biotransformation for some drugs?
What is the consequence of biotransformation for some drugs?
Where are biotransformation reactions catalyzed by enzymes located?
Where are biotransformation reactions catalyzed by enzymes located?
Flashcards
Main Biotransformation Organ
Main Biotransformation Organ
The liver is the primary organ responsible for the biotransformation of drugs in the body.
Purpose of Biotransformation
Purpose of Biotransformation
Biotransformation converts drugs into more polar, water-soluble compounds, facilitating their excretion via the kidneys.
Drug Excreted Unchanged
Drug Excreted Unchanged
An example is Furosemide.
Consequence of Biotransformation
Consequence of Biotransformation
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Location of Biotransformation Enzymes
Location of Biotransformation Enzymes
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