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Questions and Answers
Which organ is the most important for drug biotransformation?
Which organ is the most important for drug biotransformation?
- Kidney
- Liver (correct)
- Gut mucosa
- Lungs
What is the primary purpose of drug biotransformation?
What is the primary purpose of drug biotransformation?
- To make drugs less polar and water-soluble
- To convert drugs into more polar, water-soluble compounds for easier excretion (correct)
- To make drugs more lipophilic and easier to absorb
- To convert drugs into active metabolites
Which of the following drugs undergoes biotransformation to produce an active metabolite?
Which of the following drugs undergoes biotransformation to produce an active metabolite?
- Enrofloxacin (correct)
- Furosemide
- Atenolol
- Phenobarbitone
What is the consequence of biotransformation for some drugs like Paracetamol?
What is the consequence of biotransformation for some drugs like Paracetamol?
Which type of enzymes catalyze biotransformation reactions?
Which type of enzymes catalyze biotransformation reactions?
What is the term for the study of drug action on the body?
What is the term for the study of drug action on the body?
Which of the following is an example of drug action 'on the cell membrane'?
Which of the following is an example of drug action 'on the cell membrane'?
What is the term for the ability of a drug to bind to a receptor?
What is the term for the ability of a drug to bind to a receptor?
Which substance binds to the receptor and has affinity but no intrinsic activity?
Which substance binds to the receptor and has affinity but no intrinsic activity?
What is the term for a substance that binds with low intrinsic activity and may act as an agonist or antagonist?
What is the term for a substance that binds with low intrinsic activity and may act as an agonist or antagonist?
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