Drug Biotransformation Quiz
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Questions and Answers

Which organ is the most important for drug biotransformation?

  • Kidney
  • Liver (correct)
  • Gut mucosa
  • Lungs
  • What is the primary purpose of drug biotransformation?

  • To make drugs less polar and water-soluble
  • To convert drugs into more polar, water-soluble compounds for easier excretion (correct)
  • To make drugs more lipophilic and easier to absorb
  • To convert drugs into active metabolites
  • Which of the following drugs undergoes biotransformation to produce an active metabolite?

  • Enrofloxacin (correct)
  • Furosemide
  • Atenolol
  • Phenobarbitone
  • What is the consequence of biotransformation for some drugs like Paracetamol?

    <p>Conversion into an active metabolite</p> Signup and view all the answers

    Which type of enzymes catalyze biotransformation reactions?

    <p>Liver microsomal enzymes</p> Signup and view all the answers

    What is the term for the study of drug action on the body?

    <p>Pharmacodynamics</p> Signup and view all the answers

    Which of the following is an example of drug action 'on the cell membrane'?

    <p>Acting on specific receptors e.g. histamine</p> Signup and view all the answers

    What is the term for the ability of a drug to bind to a receptor?

    <p>Affinity</p> Signup and view all the answers

    Which substance binds to the receptor and has affinity but no intrinsic activity?

    <p>Antagonist</p> Signup and view all the answers

    What is the term for a substance that binds with low intrinsic activity and may act as an agonist or antagonist?

    <p>Partial agonist</p> Signup and view all the answers

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