Pharmacology: Growth Factors for Leukopoiesis
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Questions and Answers

What is the primary mechanism of action of anticoagulants such as heparin, enoxaparin, and dalteparin?

  • Activating antithrombin to prevent clotting (correct)
  • Directly inhibiting thrombin
  • Inhibiting the production of vitamin K
  • Preventing platelets from clumping together

What is a major contraindication for the use of warfarin?

  • Dissecting aneurysm
  • Pregnancy (correct)
  • Hemophilia
  • Hypertension

What is the primary adverse effect of direct thrombin inhibitors such as dabigatran, bivalirudin, and lepirudin?

  • Gastrointestinal discomfort
  • Hypotension
  • Bleeding (correct)
  • Hepatitis

What is the primary mechanism of action of rivaroxaban?

<p>Directly inhibiting Factor XA (A)</p> Signup and view all the answers

What is a common nursing intervention for patients taking anticoagulants?

<p>Monitor labs and educate patients on bleeding precautions (C)</p> Signup and view all the answers

What is a specific consideration for the administration of dabigatran?

<p>Use within 30 days of opening (C)</p> Signup and view all the answers

What is the primary effect of Filgrastim on the body?

<p>It stimulates the bone marrow to produce neutrophils. (A)</p> Signup and view all the answers

What is a common adverse effect of Sargramostim?

<p>Bone pain (C)</p> Signup and view all the answers

Which of the following is a contraindication for Oprelvekin?

<p>Bone cancer (C)</p> Signup and view all the answers

What is the primary action of Oprelvekin?

<p>It increases the production of platelets. (B)</p> Signup and view all the answers

What is a precaution for using Filgrastim?

<p>Use cautiously in patients with bone cancer (B)</p> Signup and view all the answers

What is a common adverse effect of Sargramostim and Filgrastim?

<p>Bone pain (B)</p> Signup and view all the answers

What is the primary goal of thrombolytic medications?

<p>To dissolve blood clots (C)</p> Signup and view all the answers

What is a common adverse effect of growth factor medications?

<p>All of the above (D)</p> Signup and view all the answers

What is a contraindication for thrombolytic medications?

<p>Prior intracranial hemorrhage (B)</p> Signup and view all the answers

Why should H2 blockers or PPIs be added to thrombolytic medications?

<p>To prevent bleeding (A)</p> Signup and view all the answers

What is the primary goal of nursing interventions for thrombolytic medications?

<p>To monitor for bleeding (C)</p> Signup and view all the answers

What is a unique aspect of administering thrombolytic medications?

<p>They must be administered in a 3-hour window (A)</p> Signup and view all the answers

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