Pharmacology: Growth Factors for Leukopoiesis

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What is the primary mechanism of action of anticoagulants such as heparin, enoxaparin, and dalteparin?

Activating antithrombin to prevent clotting (correct)

Directly inhibiting thrombin

Inhibiting the production of vitamin K

Preventing platelets from clumping together

What is a major contraindication for the use of warfarin?

Dissecting aneurysm

Pregnancy (correct)

Hemophilia

Hypertension

What is the primary adverse effect of direct thrombin inhibitors such as dabigatran, bivalirudin, and lepirudin?

Gastrointestinal discomfort

Hypotension

Bleeding (correct)

Hepatitis

What is the primary mechanism of action of rivaroxaban?

Directly inhibiting Factor XA Signup and view all the answers

What is a common nursing intervention for patients taking anticoagulants?

Monitor labs and educate patients on bleeding precautions Signup and view all the answers

What is a specific consideration for the administration of dabigatran?

Use within 30 days of opening Signup and view all the answers

What is the primary effect of Filgrastim on the body?

It stimulates the bone marrow to produce neutrophils. Signup and view all the answers

What is a common adverse effect of Sargramostim?

Bone pain Signup and view all the answers

Which of the following is a contraindication for Oprelvekin?

Bone cancer Signup and view all the answers

What is the primary action of Oprelvekin?

It increases the production of platelets. Signup and view all the answers

What is a precaution for using Filgrastim?

Use cautiously in patients with bone cancer Signup and view all the answers

What is a common adverse effect of Sargramostim and Filgrastim?

Bone pain Signup and view all the answers

What is the primary goal of thrombolytic medications?

To dissolve blood clots Signup and view all the answers

What is a common adverse effect of growth factor medications?

All of the above Signup and view all the answers

What is a contraindication for thrombolytic medications?

Prior intracranial hemorrhage Signup and view all the answers

Why should H2 blockers or PPIs be added to thrombolytic medications?

To prevent bleeding Signup and view all the answers

What is the primary goal of nursing interventions for thrombolytic medications?

To monitor for bleeding Signup and view all the answers

What is a unique aspect of administering thrombolytic medications?

They must be administered in a 3-hour window Signup and view all the answers