Pharmacology Exam 1: GERD and Peptic Ulcer Disease Takeaways

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Questions and Answers

What is the mechanism of action of H2 blockers like famotidine and ranitidine?

  • Inhibit H+/K+ pump in parietal cells
  • Act as anti-secretory agents
  • Increase blood sugar and blood pressure
  • Inhibit histamine and gastric acid secretion (correct)

Which medication is considered the drug of choice for erosive esophagitis for a duration of 8 weeks?

  • Cimetidine (Tagamet)
  • Misoprostol (Cytotec)
  • Omeprazole (correct)
  • Metoclopramide (Reglan)

What are the concerns associated with prolonged use of proton pump inhibitors (PPIs)?

  • Peripheral neuropathy and metallic taste
  • Pneumonia, C.diff, and B12 deficiencies (correct)
  • Hypoglycemia and hypotension
  • Increased risk of hemorrhoids

Which medication is known for causing a disulfiram reaction when combined with alcohol?

<p>Metronidazole (Flagyl) (D)</p> Signup and view all the answers

What is the main function of antacids?

<p>Convert acid into salt and water, working immediately (A)</p> Signup and view all the answers

Which medication is the only over-the-counter option for nausea that can be used for up to an hour?

<p>Emetrol (A)</p> Signup and view all the answers

Which class of medications works by blocking dopamine and has a warning against intravenous administration for one of its members?

<p>Phenothiazines (D)</p> Signup and view all the answers

"Aprepitant" and "Fosaprepitant" are examples of which class of medications used to treat chemotherapy-induced nausea and vomiting?

<p>Substance P/Neurokinin 1 receptor antagonists (A)</p> Signup and view all the answers

"Witch Hazel" and "Phenylephrine" are used for which condition?

<p>Hemorrhoids (A)</p> Signup and view all the answers

"Hydrocortisone" is used for which condition?

<p>Hemorrhoids (B)</p> Signup and view all the answers

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