Pharmacology: Drug Receptor Interaction

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Questions and Answers

What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

  • Efficacy (correct)
  • Therapeutic Index
  • Affinity
  • Potency

Which type of drug binds to the receptor but does not produce an effect, and has three subtypes: physical, chemical, and pharmacological?

  • Antagonist (correct)
  • Intrinsic activity
  • Partial agonist
  • Agonist

What is the ratio of the lethal dose (LD50) to the effective dose (ED50) of a drug?

  • Therapeutic Index (correct)
  • Intrinsic activity
  • Potency
  • Affinity

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

<p>Covalent bond (B)</p> Signup and view all the answers

What is the term for the amount of a drug which cures about 50% of the people who take it?

<p>Effective dose (B)</p> Signup and view all the answers

Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

<p>Passive diffusion (D)</p> Signup and view all the answers

Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

<p>Systemic antacids (A)</p> Signup and view all the answers

Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

<p>Sucralfate (B)</p> Signup and view all the answers

Which drugs cause a decrease in peristalsis and gastric juice volume without decreasing the pH, such as propanthelin and clidinum bromide?

<p>Anti-cholinergic drugs (B)</p> Signup and view all the answers

Which type of drugs inhibit pumps responsible for the secretion of H+ ions into the stomach lumen, such as omeprazol and lansoprazol?

<p>Proton pump inhibitors (B)</p> Signup and view all the answers

What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

<p>Efficacy (C)</p> Signup and view all the answers

Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

<p>Systemic antacids such as sodium bicarbonate (C)</p> Signup and view all the answers

Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

<p>Sucralfate (D)</p> Signup and view all the answers

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

<p>Ionic bond (C)</p> Signup and view all the answers

Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

<p>Passive diffusion (C)</p> Signup and view all the answers

What is the term for the tendency of a drug to form a combination with a receptor?

<p>Affinity (D)</p> Signup and view all the answers

Which type of drugs bind to the receptor but do not produce an effect, and have three subtypes: physical, chemical, and pharmacological?

<p>Antagonist (D)</p> Signup and view all the answers

What is the term for the amount of drug which leads to death of 50% of people who take it?

<p>Lethal Dose (LD50) (C)</p> Signup and view all the answers

What is the term for the ratio of LD50 to ED50?

<p>Therapeutic Index (A)</p> Signup and view all the answers

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

<p>Covalent bond (D)</p> Signup and view all the answers

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