Pharmacology: Drug Receptor Interaction

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20 Questions

What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

Efficacy

Which type of drug binds to the receptor but does not produce an effect, and has three subtypes: physical, chemical, and pharmacological?

Antagonist

What is the ratio of the lethal dose (LD50) to the effective dose (ED50) of a drug?

Therapeutic Index

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

Covalent bond

What is the term for the amount of a drug which cures about 50% of the people who take it?

Effective dose

Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

Passive diffusion

Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

Systemic antacids

Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

Sucralfate

Which drugs cause a decrease in peristalsis and gastric juice volume without decreasing the pH, such as propanthelin and clidinum bromide?

Anti-cholinergic drugs

Which type of drugs inhibit pumps responsible for the secretion of H+ ions into the stomach lumen, such as omeprazol and lansoprazol?

Proton pump inhibitors

What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

Efficacy

Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

Systemic antacids such as sodium bicarbonate

Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

Sucralfate

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

Ionic bond

Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

Passive diffusion

What is the term for the tendency of a drug to form a combination with a receptor?

Affinity

Which type of drugs bind to the receptor but do not produce an effect, and have three subtypes: physical, chemical, and pharmacological?

Antagonist

What is the term for the amount of drug which leads to death of 50% of people who take it?

Lethal Dose (LD50)

What is the term for the ratio of LD50 to ED50?

Therapeutic Index

Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

Covalent bond

Test your knowledge of drug receptor interaction in pharmacology. Explore concepts such as affinity, intrinsic activity, efficacy, potency, agonists, and antagonists.

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