Pharmacology: Drug Receptor Interaction
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Questions and Answers

What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

  • Efficacy (correct)
  • Therapeutic Index
  • Affinity
  • Potency
  • Which type of drug binds to the receptor but does not produce an effect, and has three subtypes: physical, chemical, and pharmacological?

  • Antagonist (correct)
  • Intrinsic activity
  • Partial agonist
  • Agonist
  • What is the ratio of the lethal dose (LD50) to the effective dose (ED50) of a drug?

  • Therapeutic Index (correct)
  • Intrinsic activity
  • Potency
  • Affinity
  • Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

    <p>Covalent bond</p> Signup and view all the answers

    What is the term for the amount of a drug which cures about 50% of the people who take it?

    <p>Effective dose</p> Signup and view all the answers

    Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

    <p>Passive diffusion</p> Signup and view all the answers

    Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

    <p>Systemic antacids</p> Signup and view all the answers

    Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

    <p>Sucralfate</p> Signup and view all the answers

    Which drugs cause a decrease in peristalsis and gastric juice volume without decreasing the pH, such as propanthelin and clidinum bromide?

    <p>Anti-cholinergic drugs</p> Signup and view all the answers

    Which type of drugs inhibit pumps responsible for the secretion of H+ ions into the stomach lumen, such as omeprazol and lansoprazol?

    <p>Proton pump inhibitors</p> Signup and view all the answers

    What is the term for the maximal degree of effectiveness of a drug, also known as intrinsic activity?

    <p>Efficacy</p> Signup and view all the answers

    Which type of antacids is absorbed and may cause alkalosis, sodium retention, and edema?

    <p>Systemic antacids such as sodium bicarbonate</p> Signup and view all the answers

    Which drugs promote peptic ulcer by forming a paste that selectively adheres to the peptic ulcer base, acting as a barrier for acid, pepsin, and bile salt diffusion?

    <p>Sucralfate</p> Signup and view all the answers

    Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

    <p>Ionic bond</p> Signup and view all the answers

    Which mechanism of drug transport involves the movement of drug molecules from high to low concentration without the involvement of a carrier?

    <p>Passive diffusion</p> Signup and view all the answers

    What is the term for the tendency of a drug to form a combination with a receptor?

    <p>Affinity</p> Signup and view all the answers

    Which type of drugs bind to the receptor but do not produce an effect, and have three subtypes: physical, chemical, and pharmacological?

    <p>Antagonist</p> Signup and view all the answers

    What is the term for the amount of drug which leads to death of 50% of people who take it?

    <p>Lethal Dose (LD50)</p> Signup and view all the answers

    What is the term for the ratio of LD50 to ED50?

    <p>Therapeutic Index</p> Signup and view all the answers

    Which type of bond between a drug and a receptor may be irreversible due to the hardness of force between them?

    <p>Covalent bond</p> Signup and view all the answers

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