Podcast
Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App
Questions and Answers
What does intrinsic activity refer to in pharmacology?
What does intrinsic activity refer to in pharmacology?
- The ability of a drug to produce action after binding to a receptor (correct)
- The amount of drug administered
- The time it takes for a drug to take effect
- The ability of a drug to bind to a receptor
Which type of drug has the highest intrinsic activity?
Which type of drug has the highest intrinsic activity?
- Partial Agonist
- Antagonist
- Inverse Agonist
- Agonist (correct)
What defines an inverse agonist?
What defines an inverse agonist?
- It produces action similar to an agonist
- It produces an opposite action to that of an agonist (correct)
- It has the same effect as an antagonist
- It enhances the effects of other drugs
What is the intrinsic activity of a drug classified as a partial agonist?
What is the intrinsic activity of a drug classified as a partial agonist?
Signup and view all the answers
Which statement is true regarding antagonists?
Which statement is true regarding antagonists?
Signup and view all the answers
Flashcards are hidden until you start studying
Study Notes
Drug Binding and Action
- Affinity refers to a drug's ability to bind to a receptor, which is crucial for its function.
- Intrinsic activity indicates a drug's capability to produce a biological effect once it binds to a receptor.
Drug Classification Based on Intrinsic Activity
- Agonist: Drugs that bind to receptors and activate them, producing a maximum response (+1).
- Partial Agonist: Drugs that bind to receptors and activate them but produce a less than maximum response (between 0 and +1).
- Inverse Agonist: Drugs that bind to receptors and induce an opposite effect compared to agonists (-ve).
- Antagonist: Drugs that do not activate receptors but block or interfere with the action of agonists, having no intrinsic activity themselves (0).
Summary of Intrinsic Activities
- Maximum intrinsic activity (Agonist): Full response achieved when binding.
- Submaximum intrinsic activity (Partial Agonist): Weaker response compared to full agonists.
- Opposite action (Inverse Agonist): Reverses the effects of agonists.
- No intrinsic action (Antagonist): Prevents receptor activation without direct activation.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
