Pharmacology: Clopidogrel and Omeprazole Interaction Quiz
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Questions and Answers

What is the reason for the required PPI therapy when using clopidogrel with aspirin?

  • To lower cholesterol levels
  • To reduce blood pressure
  • To enhance drug absorption
  • To prevent gastric bleeding (correct)

Which enzyme does Omeprazole inhibit that is involved in the biotransformation of clopidogrel?

  • CYP2C19 (correct)
  • CYP2C9
  • CYP1A2
  • CYP3A4

Why does the concomitant use of Omeprazole and clopidogrel increase the risk for stent thrombosis?

  • Metabolic interaction
  • Decreased drug efficacy
  • Reduced gastrointestinal side effects
  • Increased platelet aggregation (correct)

Which medication should not be given with calcium IV solution due to the risk of precipitation in vital organs?

<p>Ceftriaxone (C)</p> Signup and view all the answers

What is the risk associated with giving two NSAIDs together to children?

<p>Respiratory failure (B)</p> Signup and view all the answers

Why should antibiotics injection not be mixed with other injectable medications?

<p>To prevent physical and chemical incompatibility (C)</p> Signup and view all the answers

What is the concern when giving multivitamins medications without lab analysis?

<p>Brain stroke (A)</p> Signup and view all the answers

Why is it advised not to mix ceftriaxone vial with calcium IV solution?

<p>To avoid precipitation in vital organs (D)</p> Signup and view all the answers

What is the purpose of PPI therapy when using clopidogrel with aspirin?

<p>To prevent gastric bleeding (C)</p> Signup and view all the answers

Why should Omeprazole not be used concomitantly with clopidogrel?

<p>It inhibits CYP2C19 enzyme (D)</p> Signup and view all the answers

What can happen if two NSAIDs are given together to children?

<p>Exacerbation of renal impairment (C)</p> Signup and view all the answers

Why should multivitamins medications not be given without lab analysis?

<p>To prevent vitamin toxicity (A)</p> Signup and view all the answers

What is the concern when antibiotics injections are mixed with other injectable medications?

<p>Physical and chemical incompatibility (A)</p> Signup and view all the answers

Which medication should not be given together with calcium IV solution to avoid vital organ precipitation?

<p>Warfarin (A)</p> Signup and view all the answers

'Don't mix antibiotics injection with any other injectable medications' is mainly to avoid:

<p>Physical &amp; chemical incompatibility (C)</p> Signup and view all the answers

'Don't Give TWO NSAID’s together for children' primarily due to:

<p>Renal impairment exacerbation (D)</p> Signup and view all the answers

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