Pharmacology: Clopidogrel and Omeprazole Interaction Quiz

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16 Questions

What is the reason for the required PPI therapy when using clopidogrel with aspirin?

To prevent gastric bleeding

Which enzyme does Omeprazole inhibit that is involved in the biotransformation of clopidogrel?

CYP2C19

Why does the concomitant use of Omeprazole and clopidogrel increase the risk for stent thrombosis?

Increased platelet aggregation

Which medication should not be given with calcium IV solution due to the risk of precipitation in vital organs?

Ceftriaxone

What is the risk associated with giving two NSAIDs together to children?

Respiratory failure

Why should antibiotics injection not be mixed with other injectable medications?

To prevent physical and chemical incompatibility

What is the concern when giving multivitamins medications without lab analysis?

Brain stroke

Why is it advised not to mix ceftriaxone vial with calcium IV solution?

To avoid precipitation in vital organs

What is the purpose of PPI therapy when using clopidogrel with aspirin?

To prevent gastric bleeding

Why should Omeprazole not be used concomitantly with clopidogrel?

It inhibits CYP2C19 enzyme

What can happen if two NSAIDs are given together to children?

Exacerbation of renal impairment

Why should multivitamins medications not be given without lab analysis?

To prevent vitamin toxicity

What is the concern when antibiotics injections are mixed with other injectable medications?

Physical and chemical incompatibility

Which medication should not be given together with calcium IV solution to avoid vital organ precipitation?

Warfarin

'Don't mix antibiotics injection with any other injectable medications' is mainly to avoid:

Physical & chemical incompatibility

'Don't Give TWO NSAID’s together for children' primarily due to:

Renal impairment exacerbation

Test your knowledge on the interaction between clopidogrel and omeprazole in pharmacology. Learn about the need for PPI therapy when using clopidogrel alongside aspirin, and the risk factors associated with combining omeprazole and clopidogrel.

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