Pharmacology Basics

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6 Questions

What is the primary focus of clinical pharmacology?

Study of the adverse effects of drugs

What is the process of a drug entering the bloodstream?

Absorption

What is the term for the immune system response to a drug?

Allergic Reactions

What is the study of the molecular mechanisms of drug action?

Molecular Pharmacology

What is the term for the effects of combining multiple drugs?

Interactions

What is the term for a drug that binds to receptors but only partially activates them?

Partial Agonists

Study Notes

What is Pharmacology?

  • Study of the effects of drugs on living organisms
  • Involves understanding the interactions between drugs and biological systems
  • Encompasses pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body)

Types of Pharmacology

  • Clinical Pharmacology: study of drugs in humans, focusing on therapeutic uses and adverse effects
  • Toxicology: study of the adverse effects of drugs and other substances
  • Neuropharmacology: study of the effects of drugs on the nervous system
  • Molecular Pharmacology: study of the molecular mechanisms of drug action

Pharmacokinetics

  • Absorption: process of a drug entering the bloodstream
  • Distribution: process of a drug spreading throughout the body
  • Metabolism: process of a drug being broken down by the body
  • Excretion: process of a drug being eliminated from the body

Pharmacodynamics

  • Receptors: molecules on the surface of cells that interact with drugs
  • Agonists: drugs that bind to receptors and activate them
  • Antagonists: drugs that bind to receptors and block their activation
  • Partial Agonists: drugs that bind to receptors but only partially activate them

Drug-Body Interactions

  • Side Effects: unintended effects of a drug
  • Interactions: effects of combining multiple drugs
  • Allergic Reactions: immune system responses to a drug
  • Tolerance: decreased response to a drug over time
  • Dependence: physical or psychological need for a drug

What is Pharmacology?

  • Study of the effects of drugs on living organisms, including understanding interactions between drugs and biological systems
  • Encompasses two main areas: pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body)

Types of Pharmacology

  • Clinical Pharmacology: focuses on therapeutic uses and adverse effects of drugs in humans
  • Toxicology: studies the adverse effects of drugs and other substances
  • Neuropharmacology: explores the effects of drugs on the nervous system
  • Molecular Pharmacology: examines the molecular mechanisms of drug action

Pharmacokinetics

  • Absorption: process by which a drug enters the bloodstream
  • The rate and extent of absorption affect the drug's concentration and duration of action
  • Distribution: process of a drug spreading throughout the body, influenced by factors such as blood flow and tissue binding
  • Metabolism: process of a drug being broken down by the body, often involving enzyme-catalyzed reactions
  • Excretion: process of a drug being eliminated from the body, primarily through the kidneys and liver

Pharmacodynamics

  • Receptors: molecules on the surface of cells that interact with drugs, triggering specific responses
  • Agonists: drugs that bind to receptors, activating them and producing a response
  • Antagonists: drugs that bind to receptors, blocking their activation and response
  • Partial Agonists: drugs that bind to receptors, producing a partial response

Drug-Body Interactions

  • Side Effects: unintended effects of a drug, often predictable and manageable
  • Interactions: effects of combining multiple drugs, which can be synergistic, additive, or antagonistic
  • Allergic Reactions: immune system responses to a drug, ranging from mild to severe
  • Tolerance: decreased response to a drug over time, often due to adaptive changes in the body
  • Dependence: physical or psychological need for a drug, often accompanied by withdrawal symptoms

Learn about the study of the effects of drugs on living organisms, including pharmacokinetics and pharmacodynamics, and types of pharmacology like clinical pharmacology and toxicology.

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