Podcast
Questions and Answers
Which of the following factors affect drug distribution?
Which of the following factors affect drug distribution?
- Blood flow
- Cardiac output
- Plasma protein binding
- All of the above (correct)
Which organ has the highest blood flow?
Which organ has the highest blood flow?
- Liver
- Kidneys
- Heart (correct)
- Brain
Which protein is the predominant plasma binding protein?
Which protein is the predominant plasma binding protein?
- Albumin (correct)
- Globulin
- Fibrinogen
- Hemoglobin
What type of drugs are highly soluble in fats and non-polar solutions?
What type of drugs are highly soluble in fats and non-polar solutions?
What does the rate of drug distribution depend on?
What does the rate of drug distribution depend on?
What is the blood brain barrier?
What is the blood brain barrier?
Can disease states affect the ability of drugs to pass through the blood brain barrier?
Can disease states affect the ability of drugs to pass through the blood brain barrier?
Which of the following is NOT a specialized barrier or compartment that affects drug distribution?
Which of the following is NOT a specialized barrier or compartment that affects drug distribution?
Which of the following is NOT a factor that can affect the volume of distribution (Vd) of a drug?
Which of the following is NOT a factor that can affect the volume of distribution (Vd) of a drug?
Which of the following molecules is LEAST likely to have a high plasma steady state concentration (Css)?
Which of the following molecules is LEAST likely to have a high plasma steady state concentration (Css)?
Which of the following statements about the volume of distribution (Vd) is TRUE?
Which of the following statements about the volume of distribution (Vd) is TRUE?
Which model of drug distribution assumes rapid mixing of the drug in plasma and rapid equilibrium with drug in extravascular tissues?
Which model of drug distribution assumes rapid mixing of the drug in plasma and rapid equilibrium with drug in extravascular tissues?
Which of the following is NOT a clinical relevance of the volume of distribution (Vd)?
Which of the following is NOT a clinical relevance of the volume of distribution (Vd)?
Which of the following statements about the volume of distribution (Vd) is FALSE?
Which of the following statements about the volume of distribution (Vd) is FALSE?
Which of the following is NOT a factor that can affect the time taken to reach the plasma steady state concentration (Css) of a drug?
Which of the following is NOT a factor that can affect the time taken to reach the plasma steady state concentration (Css) of a drug?
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