Podcast
Questions and Answers
What is another name for Benzyl penicillin?
What is another name for Benzyl penicillin?
Which antibiotic commonly causes Red Man Syndrome?
Which antibiotic commonly causes Red Man Syndrome?
What is the primary target of Beta-lactam antibiotics?
What is the primary target of Beta-lactam antibiotics?
Why are tetracyclines contraindicated in children and neonates?
Why are tetracyclines contraindicated in children and neonates?
Signup and view all the answers
What is the target for clavulanic acid?
What is the target for clavulanic acid?
Signup and view all the answers
Which antibiotic is considered the 'last resort' for severe infections in neonates?
Which antibiotic is considered the 'last resort' for severe infections in neonates?
Signup and view all the answers
Which antibiotic can cause cross-sensitivity with penicillins?
Which antibiotic can cause cross-sensitivity with penicillins?
Signup and view all the answers
Which antibiotic causes thrombocytopenia as the most common fatal reaction?
Which antibiotic causes thrombocytopenia as the most common fatal reaction?
Signup and view all the answers
What is the first therapeutically useful quinolone antibacterial agent?
What is the first therapeutically useful quinolone antibacterial agent?
Signup and view all the answers
What is the combination of trimethoprim and sulfamethoxazole also known as?
What is the combination of trimethoprim and sulfamethoxazole also known as?
Signup and view all the answers
Which enzymes are targeted by quinolone antibacterial agents?
Which enzymes are targeted by quinolone antibacterial agents?
Signup and view all the answers
What is used to prevent peripheral neuropathy in patients taking INH?
What is used to prevent peripheral neuropathy in patients taking INH?
Signup and view all the answers
Which drug is a sulfonamide used in burns?
Which drug is a sulfonamide used in burns?
Signup and view all the answers
What does trimethoprim inhibit?
What does trimethoprim inhibit?
Signup and view all the answers
Which anti-TB drug causes urine and tears to have a reddish color?
Which anti-TB drug causes urine and tears to have a reddish color?
Signup and view all the answers
Study Notes
Antibiotics
- Benzyl penicillin is also known as Penicillin G.
- Cefepime is a fourth-generation cephalosporin.
- Vancomycin can cause Red Man Syndrome.
- Clarithromycin is a methylated erythromycin.
Adverse Reactions
- Chloramphenicol can cause thrombocytopenia, which is fatal.
- Tetracyclines are contraindicated in children and neonates because they can cause discoloration of teeth and phototoxicity.
Mechanism of Action
- Beta-lactams primarily target the cell wall.
- Clavulanic acid targets β-lactamase.
Therapeutic Applications
- Colistin is usually the "last resort" antibiotic treatment in neonates with severe infections.
- Co-trimoxazole is a combination of trimethoprim and sulfamethoxazole.
Quinolones
- Nalidixic acid was the first therapeutically useful quinolone antibacterial agent.
- Quinolone antibacterial agents target topoisomerases.
Anti-Tuberculosis Drugs
- The combination therapy in the treatment of tuberculosis contains Ethambutol, Rifampin, and Isoniazid, but not Streptomycin.
- Pyridoxine can prevent peripheral neuropathy in patients taking INH.
Sulfonamides
- Silver sulfadiazine is a sulfonamide used in burns.
- Trimethoprim inhibits dihydrofolate reductase.
Miscellaneous
- Rifampin can cause urine and tears to turn reddish in color.
- Metronidazole is a nitroimidazole drug with antibiotic and antiparasitic properties.
- Levo is the more potent optical isomer of ofloxacin.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge of antibiotics with this quiz. Identify different types of antibiotics and their common names. Learn about adverse reactions associated with certain antibiotics.