Common Anti-Infectives and Immunosuppressants
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Questions and Answers

Which medication is classified as a macrolide antibiotic?

  • Vancomycin
  • Gentamicin
  • Ciprofloxacin
  • Azithromycin (correct)

Gentamicin belongs to which class of anti-infective medications?

  • Aminopenicillins
  • Aminoglycosides (correct)
  • Fluoroquinolones
  • Lincosamides

Vancomycin is primarily used to treat infections caused by what type of bacteria?

  • Acid-fast bacteria
  • Gram-positive bacteria (correct)
  • Gram-negative bacteria
  • Anaerobic bacteria

Ciprofloxacin is classified under which category of antibiotics?

<p>Fluoroquinolones (D)</p> Signup and view all the answers

Amoxicillin falls under which classification of antibiotics?

<p>Aminopenicillins (D)</p> Signup and view all the answers

Which antibiotic is a lincosamide?

<p>Clindamycin (A)</p> Signup and view all the answers

Rifampin is primarily used in the treatment of what condition?

<p>Tuberculosis (D)</p> Signup and view all the answers

Trimethoprim/Sulfamethoxazole is a combination drug that belongs to which class?

<p>Sulfonamides (A)</p> Signup and view all the answers

Which medication is classified as an antifungal?

<p>Fluconazole (B)</p> Signup and view all the answers

Valacyclovir is primarily prescribed for what type of infection?

<p>Viral (D)</p> Signup and view all the answers

Lamivudine is used as a reverse transcriptase inhibitor for the treatment of which viral infection?

<p>Hepatitis B and HIV (D)</p> Signup and view all the answers

Ritonavir belongs to which class of antiviral drugs?

<p>Protease inhibitors (A)</p> Signup and view all the answers

Enfuvirtide prevents viral entry into human cells by which mechanism?

<p>Inhibiting fusion (B)</p> Signup and view all the answers

Cyclosporine is used to suppress which component of the immune system?

<p>T cells (B)</p> Signup and view all the answers

Elvitegravir inhibits which enzyme that is essential for viral replication?

<p>Integrase (B)</p> Signup and view all the answers

Maraviroc functions as an antiretroviral drug by targeting what?

<p>CCR5 coreceptor (B)</p> Signup and view all the answers

What is the primary function of filgrastim?

<p>Colony stimulating factor (C)</p> Signup and view all the answers

Which of the following drugs requires testing for tropism before it can be prescribed, due to its mechanism of action?

<p>Maraviroc (B)</p> Signup and view all the answers

A patient with a severe penicillin allergy needs treatment for a gram-positive infection. Which of the following would be the MOST appropriate choice?

<p>Vancomycin (A)</p> Signup and view all the answers

Which medication on the list is LEAST likely to be prescribed as a first-line treatment for a common cold?

<p>Filgrastim (B)</p> Signup and view all the answers

Which drug is an aminoglycoside antibiotic?

<p>Gentamicin (A)</p> Signup and view all the answers

Which one is the antifungal?

<p>Fluconazole (D)</p> Signup and view all the answers

Which medication acts as an integrase inhibitor?

<p>Elvitegravir (D)</p> Signup and view all the answers

Which drug is an antiviral that inhibits viral fusion?

<p>Enfuvirtide (C)</p> Signup and view all the answers

A patient requires an immunosuppressant following an organ transplant. Which of these medications is MOST likely to be prescribed?

<p>Cyclosporine (D)</p> Signup and view all the answers

Which medication is NOT primarily used to treat bacterial infections?

<p>Valacyclovir (A)</p> Signup and view all the answers

In treating HIV, which drug requires consideration of a patient's viral load and CD4 count to assess its appropriateness and effectiveness?

<p>Maraviroc (A)</p> Signup and view all the answers

Which of the following medications targets DNA gyrase as its primary mechanism of action?

<p>Ciprofloxacin (C)</p> Signup and view all the answers

Which medication listed is MOST likely to cause C. difficile infection as a secondary complication?

<p>Azithromycin (B)</p> Signup and view all the answers

Which agent is most likely used in conjunction with other drugs to AMPLIFY their effect?

<p>Ritonavir (D)</p> Signup and view all the answers

Which specific mechanism of action is associated with disrupting bacterial cell wall synthesis?

<p>Vancomycin (D)</p> Signup and view all the answers

A patient exhibits drug resistance to multiple antiretroviral drugs. Which medication on the list COULD potentially have its absorption impacted by antacids containing magnesium or aluminum?

<p>Elvitegravir (B)</p> Signup and view all the answers

Which medication presents a noteworthy risk of QT interval prolongation, especially when combined with other drugs that inhibit CYP3A4?

<p>Azithromycin (D)</p> Signup and view all the answers

What aspect of Rifampin metabolism presents a major risk for polypharmacy?

<p>Induces CYP450 enzymes (B)</p> Signup and view all the answers

A patient with renal impairment is prescribed an antiviral medication for a herpes infection. Which drug requires the MOST cautious dose adjustment due to its primary route of elimination?

<p>Valacyclovir (D)</p> Signup and view all the answers

Which medication listed is used to mitigate the development of opportunistic infection in immunocompromised individuals, but does NOT directly possess antimicrobial properties in isolation?

<p>Filgrastim (C)</p> Signup and view all the answers

A patient develops severe neutropenia following chemotherapy. Which intervention MOST directly addresses this specific side effect to reduce the risk of infection?

<p>Administering filgrastim (C)</p> Signup and view all the answers

Flashcards

Azithromycin

A macrolide antibiotic used to treat various bacterial infections.

Gentamicin

An aminoglycoside antibiotic effective against gram-negative bacteria.

Vancomycin

An anti-infective glycopeptide antibiotic used to treat severe bacterial infections, especially those resistant to other antibiotics.

Ciprofloxacin

A fluoroquinolone antibiotic used to treat a variety of bacterial infections.

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Amoxicillin

An aminopenicillin antibiotic effective against a range of bacterial infections.

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Clindamycin

A lincosamide antibiotic used to treat bacterial infections.

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Rifampin

An antitubercular antibiotic used in the treatment of tuberculosis.

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Trimethoprim/Sulfamethoxazole

A sulfonamide antibiotic combination used to treat bacterial infections.

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Fluconazole

An antifungal medication used to treat fungal infections.

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Valacyclovir

An antiviral medication used to treat herpes infections.

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Lamivudine

A reverse transcriptase inhibitor (NRTI) used in the treatment of HIV/AIDS.

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Ritonavir

A protease inhibitor used in the treatment of HIV/AIDS.

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Enfuvirtide

A fusion inhibitor used in the treatment of HIV/AIDS.

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Cyclosporine

An immunosuppressant drug used to prevent organ rejection and treat autoimmune diseases.

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Elvitegravir

An integrase inhibitor used in the treatment of HIV/AIDS.

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Maraviroc

An antiretroviral/CCR5 coreceptor antagonist used in the treatment of HIV/AIDS.

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Filgristim

A colony-stimulating factor used to stimulate the production of white blood cells.

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Study Notes

  • Azithromycin is a macrolide antibiotic
  • Gentamicin is an anti-infective/aminoglycoside
  • Vancomycin is an anti-infective
  • Ciprofloxacin is an anti-infective/fluoroquinolone
  • Amoxicillin is an anti-infective/aminopenicillin
  • Clindamycin is a lincosamide antibiotic
  • Rifampin is an antitubercular/anti-infective
  • Trimethoprim/Sulfamethoxazole is a sulfonamide
  • Fluconazole is an antifungal
  • Valacyclovir is an antiviral
  • Lamivudine is a reverse transcriptase inhibitor (NRTI)
  • Ritonavir is a protease inhibitor
  • Enfuvirtide is a fusion inhibitor
  • Cyclosporine is an immunosuppressant
  • Elvitegravir is an integrase inhibitor
  • Maraviroc is an antiretroviral/CCR5 coreceptor antagonist
  • Filgristim is a colony stimulating factor

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Description

Overview of common anti-infective and immunosuppressant medications. Includes drug classes like macrolides, aminoglycosides, fluoroquinolones, and antivirals. Also covers immunosuppressants and antiretroviral medications.

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