Pharmacology: Adrenergic & Anticholinergic Drugs
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Questions and Answers

Which adrenergic drug is primarily used for life-saving interventions during anaphylaxis?

  • Epinephrine (correct)
  • Dopamine
  • Albuterol
  • Glycopyrrolate
  • What is the primary effect of beta2-adrenergic receptors at the cellular level?

  • Increase heart rate
  • Lower blood pressure
  • Cause bronchodilation (correct)
  • Enhance kidney function
  • Which of the following is an important patient teaching point for individuals taking beta-blockers?

  • Avoid all physical activity
  • Stop the medication if you feel dizzy
  • Monitor your pulse and blood pressure regularly (correct)
  • Increase your intake of caffeinated beverages
  • What is a common side effect of anticholinergic drugs like glycopyrrolate?

    <p>Blurred vision (A)</p> Signup and view all the answers

    Which cholinergic drug is used to ease urinary retention post-surgery?

    <p>Bethanechol (A)</p> Signup and view all the answers

    What is a contraindication for prescribing cholinergic drugs?

    <p>Hypotension (D)</p> Signup and view all the answers

    Which drug is commonly recognized for its use in preventing acute asthma symptoms?

    <p>Salmeterol (B)</p> Signup and view all the answers

    What should patients using anticholinergic drugs be cautious of to avoid dehydration?

    <p>Increased fluid intake (D)</p> Signup and view all the answers

    Flashcards

    Adrenergic Drugs

    Medications that mimic the Sympathetic Nervous System (SNS).

    Epinephrine

    A drug that opens bronchi and increases blood pressure, used in emergencies like anaphylaxis.

    Beta2-Adrenergic Receptors

    Receptors that cause bronchodilation, important for asthma treatment.

    Beta1-Adrenergic Receptors

    Receptors found in the heart that affect heart rate and contraction strength.

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    Anticholinergic Drugs

    Medications that block the Parasympathetic Nervous System (PNS).

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    Glycopyrrolate

    An anticholinergic used pre-surgery to decrease oral and gastrointestinal secretions.

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    Cholinergic Drugs

    Medications that stimulate the PNS by increasing acetylcholine levels.

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    Donepezil

    A cholinergic drug that improves memory in Alzheimer's but is not a cure.

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    Study Notes

    Adrenergic Drugs: Sympathetic Superpowers

    • Mimic the Sympathetic Nervous System (SNS)
    • Epinephrine: Opens bronchi, increases blood pressure (e.g., anaphylaxis)
    • Dopamine: Enhances cardiac output (e.g., shock management)
    • Key Receptors:
      • Beta2-Adrenergic: Bronchodilation (e.g., asthma)
      • Beta1-Adrenergic: Heart rate and strength of contractions
    • Patient Teaching:
      • Do not abruptly stop beta-blockers (e.g., Atenolol)
      • Monitor pulse and blood pressure regularly
      • Be aware of hypoglycemia symptoms when using beta-blockers

    Anticholinergic Drugs: PNS Blockers

    • Block the Parasympathetic Nervous System (PNS)
    • Reduce secretions, slow systems
    • Glycopyrrolate: Used pre-surgery to reduce oral and GI secretions.
    • Oxybutynin: Decreases urinary frequency, helps with bladder control.
    • Watch for:
      • Dry mouth
      • Blurred vision
      • Constipation
    • Special Notes for Active Seniors: Stay cool to prevent heat stroke due to reduced sweating.

    Cholinergic Drugs: Boosting Acetylcholine

    • Stimulate the PNS by increasing acetylcholine levels
    • Donepezil: Improves memory in Alzheimer's patients (not a cure)

    Disease-Specific Drug Applications

    • Heart Conditions: Carvedilol treats mild heart failure. Watch for worsening heart failure symptoms (edema, shortness of breath).
    • Respiratory Management: Albuterol helps during acute asthma attacks (tachycardia possible). Salmeterol prevents, but does not treat, sudden asthma symptoms.
    • Neurological Focus: Memantine manages symptoms of Alzheimer's Disease. Pyridostigmine improves swallowing in Myasthenia Gravis (take 30 minutes before meals).

    Clinical Scenarios

    • Phentolamine: Prevents tissue damage from vasopressors (e.g., dobutamine).
    • Physostigmine: Antidote for atropine overdose.

    Patient Education Essentials

    • Safety Precautions: Notify a doctor if pulse drops below 60 bpm while on beta-blockers. Avoid overheating if taking anticholinergics, stay hydrated.
    • Timing Is Everything: Apply Scopolamine Patch 4-5 hours before travel, schedule cholinergic drugs carefully with meals
    • Herbal Awareness: Ginkgo biloba increases bleeding risk when combined with aspirin.

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    Description

    Test your knowledge on adrenergic and anticholinergic drugs that influence the sympathetic and parasympathetic nervous systems. This quiz covers drug actions, key receptors, patient education, and important considerations when using these medications. Perfect for pharmacology students and healthcare professionals.

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