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Questions and Answers
Which zone of the adrenal cortex produces mineralocorticoids responsible for regulating salt and water metabolism?
Which zone of the adrenal cortex produces mineralocorticoids responsible for regulating salt and water metabolism?
What is the primary function of glucocorticoids synthesized in the middle zona fasciculata of the adrenal cortex?
What is the primary function of glucocorticoids synthesized in the middle zona fasciculata of the adrenal cortex?
Which hormone controls the secretion of the two inner zones of the adrenal cortex?
Which hormone controls the secretion of the two inner zones of the adrenal cortex?
What serves as feedback inhibitors of ACTH and CRH secretion?
What serves as feedback inhibitors of ACTH and CRH secretion?
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Which type of steroid hormone is synthesized by the inner zona reticularis of the adrenal cortex?
Which type of steroid hormone is synthesized by the inner zona reticularis of the adrenal cortex?
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How do glucocorticoids promote normal intermediary metabolism?
How do glucocorticoids promote normal intermediary metabolism?
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What is the principal human glucocorticoid?
What is the principal human glucocorticoid?
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What is the primary role of glucocorticoids in increasing resistance to stress?
What is the primary role of glucocorticoids in increasing resistance to stress?
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What differentiates corticosteroids in their activity?
What differentiates corticosteroids in their activity?
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How do glucocorticoids influence the inflammatory response?
How do glucocorticoids influence the inflammatory response?
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Study Notes
Adrenal Cortex Zones
- Mineralocorticoids, responsible for regulating salt and water metabolism, are produced in the zona glomerulosa of the adrenal cortex.
Glucocorticoids
- Glucocorticoids, synthesized in the zona fasciculata, play a crucial role in regulating carbohydrate, protein, and fat metabolism.
- The primary function of glucocorticoids is to promote normal intermediary metabolism.
Regulation of Adrenal Cortex
- The hormone ACTH (Adrenocorticotropic Hormone) controls the secretion of the two inner zones of the adrenal cortex.
- Corticosterone serves as a feedback inhibitor of ACTH and CRH secretion.
Zona Reticularis
- The inner zona reticularis of the adrenal cortex synthesizes androgens, a type of steroid hormone.
Glucocorticoids and Stress
- The principal human glucocorticoid is cortisol.
- Glucocorticoids play a primary role in increasing resistance to stress by promoting the breakdown of fat, protein, and carbohydrates to produce energy.
Corticosteroids
- Corticosteroids differ in their activity based on their ability to affect glucocorticoid receptors or mineralocorticoid receptors.
Inflammatory Response
- Glucocorticoids suppress the inflammatory response by reducing the production of pro-inflammatory cytokines.
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Description
Test your knowledge on the adrenal hormones, adrenocorticosteroids, and adrenocortical antagonists in Pharmacology 3. This quiz covers the secretion, types, and functions of corticosteroids produced by the adrenal cortex.
