Podcast
Questions and Answers
How do glucocorticoids promote normal intermediary metabolism?
How do glucocorticoids promote normal intermediary metabolism?
- By enhancing expression of gluconeogenesis enzymes (correct)
- By inhibiting lipolysis
- By decreasing hepatic glucose production
- By reducing amino acid mobilization
What is the main role of glucocorticoids in increasing resistance to stress?
What is the main role of glucocorticoids in increasing resistance to stress?
- Raising plasma glucose levels (correct)
- Mobilizing amino acids for energy
- Lowering plasma glucose levels
- Inhibiting lipolysis
How do glucocorticoids affect blood cell levels in plasma?
How do glucocorticoids affect blood cell levels in plasma?
- Decrease hemoglobin and erythrocytes
- Decrease eosinophils, basophils, and lymphocytes
- Increase platelets and polymorphonuclear leukocytes (correct)
- Increase eosinophils and monocytes
What is the most important therapeutic property of glucocorticoids?
What is the most important therapeutic property of glucocorticoids?
Which of the following is NOT a way in which glucocorticoids alter blood cell levels in plasma?
Which of the following is NOT a way in which glucocorticoids alter blood cell levels in plasma?
What happens to glucose synthesis when glucocorticoids stimulate lipolysis?
What happens to glucose synthesis when glucocorticoids stimulate lipolysis?
What is the main cause of Cushing syndrome?
What is the main cause of Cushing syndrome?
What is the mechanism by which adrenal hormones influence the inflammatory response?
What is the mechanism by which adrenal hormones influence the inflammatory response?
Which hormone suppresses cortisol release in normal individuals but not in those with Cushing syndrome?
Which hormone suppresses cortisol release in normal individuals but not in those with Cushing syndrome?
What is a frequent cause of iatrogenic Cushing syndrome?
What is a frequent cause of iatrogenic Cushing syndrome?
How do high levels of glucocorticoids affect the endocrine system?
How do high levels of glucocorticoids affect the endocrine system?
In congenital adrenal hyperplasia, what leads to virilization in females?
In congenital adrenal hyperplasia, what leads to virilization in females?
What is the primary role of mineralocorticoids in the body?
What is the primary role of mineralocorticoids in the body?
Where does aldosterone act to promote sodium reabsorption?
Where does aldosterone act to promote sodium reabsorption?
What is the main purpose of administering corticosteroids in congenital adrenal hyperplasia?
What is the main purpose of administering corticosteroids in congenital adrenal hyperplasia?
What are the consequences of elevated aldosterone levels?
What are the consequences of elevated aldosterone levels?
Which symptom can corticosteroids relieve in conditions like rheumatoid arthritis?
Which symptom can corticosteroids relieve in conditions like rheumatoid arthritis?
How do corticosteroids affect glomerular filtration?
How do corticosteroids affect glomerular filtration?
Which adverse effect is the most common due to glucocorticoids' effect on bone health?
Which adverse effect is the most common due to glucocorticoids' effect on bone health?
What is a classic symptom of excess corticosteroid replacement?
What is a classic symptom of excess corticosteroid replacement?
Which condition may occur with long-term corticosteroid therapy affecting the eyes?
Which condition may occur with long-term corticosteroid therapy affecting the eyes?
What is an adverse effect of glucocorticosteroids that may require diabetic patients to monitor their blood glucose?
What is an adverse effect of glucocorticosteroids that may require diabetic patients to monitor their blood glucose?
Which potential corticosteroid-induced effect is characterized by redistribution of body fat and a puffy face?
Which potential corticosteroid-induced effect is characterized by redistribution of body fat and a puffy face?
In what population does glucocorticoid therapy pose a risk of decreased growth as an adverse effect?
In what population does glucocorticoid therapy pose a risk of decreased growth as an adverse effect?
What can happen if corticosteroids are abruptly discontinued in a patient with suppression of the HPA axis?
What can happen if corticosteroids are abruptly discontinued in a patient with suppression of the HPA axis?
Which drug is used to treat Cushing syndrome by inhibiting gonadal and adrenal steroid hormone synthesis?
Which drug is used to treat Cushing syndrome by inhibiting gonadal and adrenal steroid hormone synthesis?
What is the primary mechanism of action of Spironolactone in treating certain conditions?
What is the primary mechanism of action of Spironolactone in treating certain conditions?
Which of the following conditions is Spironolactone NOT used for?
Which of the following conditions is Spironolactone NOT used for?
What effect does Spironolactone have on the hair follicles leading to its use in managing hirsutism?
What effect does Spironolactone have on the hair follicles leading to its use in managing hirsutism?
Which drug inhibits both gonadal and adrenal steroid hormone synthesis and is used in patients with Cushing syndrome?
Which drug inhibits both gonadal and adrenal steroid hormone synthesis and is used in patients with Cushing syndrome?
What serious consequences can occur if corticosteroids are abruptly discontinued in a patient with suppression of the HPA axis?
What serious consequences can occur if corticosteroids are abruptly discontinued in a patient with suppression of the HPA axis?
Which drug competes for the mineralocorticoid receptor and inhibits sodium reabsorption in the kidney?
Which drug competes for the mineralocorticoid receptor and inhibits sodium reabsorption in the kidney?
Inhibitors of which of the following are therapeutically useful in the treatment of patients with Cushing syndrome?
Inhibitors of which of the following are therapeutically useful in the treatment of patients with Cushing syndrome?
Which drug is effective for the management of hirsutism in women due to its antiandrogen activity on the hair follicle?
Which drug is effective for the management of hirsutism in women due to its antiandrogen activity on the hair follicle?
What could happen if a patient undergoes abrupt removal of corticosteroids without tapering according to individual tolerance?
What could happen if a patient undergoes abrupt removal of corticosteroids without tapering according to individual tolerance?
Which condition can Spironolactone effectively treat when used with other standard therapies for heart failure with reduced ejection fraction?
Which condition can Spironolactone effectively treat when used with other standard therapies for heart failure with reduced ejection fraction?
What is the primary therapeutic property of Ketoconazole that makes it useful in patients with Cushing syndrome?
What is the primary therapeutic property of Ketoconazole that makes it useful in patients with Cushing syndrome?
Which adverse effect can occur if a patient with suppression of the HPA axis is not carefully monitored during corticosteroid dose tapering?
Which adverse effect can occur if a patient with suppression of the HPA axis is not carefully monitored during corticosteroid dose tapering?
What role does Spironolactone's antiandrogen activity play in managing hirsutism in women?
What role does Spironolactone's antiandrogen activity play in managing hirsutism in women?
How does Ketoconazole impact gonadal and adrenal steroid hormone synthesis in patients with Cushing syndrome?
How does Ketoconazole impact gonadal and adrenal steroid hormone synthesis in patients with Cushing syndrome?
