Podcast
Questions and Answers
What is the mechanism of action of acetaminophen?
What is the mechanism of action of acetaminophen?
- Inhibits COX-2 in the CNS
- Enhances prostaglandins in the brain
- Inhibits COX-1 in the periphery
- Inhibits COX-1 in the CNS (correct)
Which opioid receptor subtype do codeine and morphine primarily act on?
Which opioid receptor subtype do codeine and morphine primarily act on?
- Delta-receptor
- Sigma-receptor
- Mu-receptor (correct)
- Kappa-receptor
What is a common side effect associated with opioids?
What is a common side effect associated with opioids?
- Mydriasis
- Miosis (correct)
- Hypertension
- Hyperactivity
How does lidocaine produce its pharmacological effect?
How does lidocaine produce its pharmacological effect?
Which local anesthetic acts as an agonist at TRPV1 receptors?
Which local anesthetic acts as an agonist at TRPV1 receptors?
Which antidepressant drug blocks the uptake of serotonin and norepinephrine?
Which antidepressant drug blocks the uptake of serotonin and norepinephrine?
How does carbamazepine work as an anticonvulsant?
How does carbamazepine work as an anticonvulsant?
'Capsaicin' is used for the management of which type of pain?
'Capsaicin' is used for the management of which type of pain?
'Gabapentin' has what effect on presynaptic N, L, P/Q-type voltage-gated Ca2+ channels?
'Gabapentin' has what effect on presynaptic N, L, P/Q-type voltage-gated Ca2+ channels?
'Ketamine' is primarily used for which therapeutic purpose?
'Ketamine' is primarily used for which therapeutic purpose?
What is the definition of pain according to the 2020 revised definition by the International Association for the Study of Pain (IASP)?
What is the definition of pain according to the 2020 revised definition by the International Association for the Study of Pain (IASP)?
Which chemical mediator of pain is released after tissue trauma and contributes to augmented sensitivity to stimuli in the area surrounding an injury?
Which chemical mediator of pain is released after tissue trauma and contributes to augmented sensitivity to stimuli in the area surrounding an injury?
What type of pain is associated with a maladaptive response to damage or disease of the somatosensory nervous system?
What type of pain is associated with a maladaptive response to damage or disease of the somatosensory nervous system?
Which drug class is commonly used for treating neuropathic pain due to its action on the central and/or peripheral disorder of pain modulation?
Which drug class is commonly used for treating neuropathic pain due to its action on the central and/or peripheral disorder of pain modulation?
Which term describes exaggerated sensitivity to stimuli in the area surrounding an injury?
Which term describes exaggerated sensitivity to stimuli in the area surrounding an injury?
Which drug is commonly used to treat nociceptive pain associated with inflammatory, ischemic, infectious, or mechanical injury?
Which drug is commonly used to treat nociceptive pain associated with inflammatory, ischemic, infectious, or mechanical injury?
What kind of injury or disease typically leads to nociceptive pain?
What kind of injury or disease typically leads to nociceptive pain?
What term best describes pain that occurs in the absence of active noxious stimulus?
What term best describes pain that occurs in the absence of active noxious stimulus?
What is the primary difference between nociceptive and neuropathic pain?
What is the primary difference between nociceptive and neuropathic pain?
What is the primary mechanism of action for non-steroidal anti-inflammatory drugs (NSAIDs)?
What is the primary mechanism of action for non-steroidal anti-inflammatory drugs (NSAIDs)?
What is the main difference between the mechanisms of nociceptive and neuropathic pain?
What is the main difference between the mechanisms of nociceptive and neuropathic pain?
Which of the following is a characteristic of COX-1 enzymes?
Which of the following is a characteristic of COX-1 enzymes?
Which of the following statements about aspirin is true?
Which of the following statements about aspirin is true?
Which of the following is a chronic pain disorder classified as neuropathic pain?
Which of the following is a chronic pain disorder classified as neuropathic pain?
What is the primary difference between the mechanisms of action of aspirin and ibuprofen?
What is the primary difference between the mechanisms of action of aspirin and ibuprofen?
What is the primary function of COX-2 enzymes?
What is the primary function of COX-2 enzymes?
Which of the following is a potential side effect associated with non-selective NSAIDs?
Which of the following is a potential side effect associated with non-selective NSAIDs?
Which of the following is an example of a mixed chronic pain disorder?
Which of the following is an example of a mixed chronic pain disorder?
What is the primary function of COX-3 enzymes?
What is the primary function of COX-3 enzymes?
