Non-pharmacological Treatment Methods and Therapeutic Lifestyle Changes (TLCs)
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Questions and Answers

What is the primary objective of dietary therapy in non-pharmacological treatment?

  • To encourage physical activity of high intensity
  • To achieve a desirable body weight (correct)
  • To increase intake of total fat, saturated fat, and cholesterol
  • To promote smoking cessation

    • What is the main effect of fish oil supplementation?

  • Has no effect on lipid levels
  • Elevates triglycerides and VLDL-C levels (correct)
  • Reduces total and LDL cholesterol levels
  • Decreases bile acid pool size

    • How do Bile Acid Resins (BARs) lower LDL levels?

  • By decreasing bile acid synthesis
  • By stimulating hepatic synthesis of cholesterol
  • By increasing the number of LDL-receptors on hepatocyte membranes (correct)
  • By elevating the bile acid pool size

    • What are the common adverse effects of Bile Acid Resins (BARs)?

    <p>Gastrointestinal complaints like constipation and bloating</p> Signup and view all the answers

    Which non-pharmacological treatment is recommended to assist patients with smoking cessation and control of hypertension?

    <p>Weight reduction</p> Signup and view all the answers

    What is the recommended duration of moderate intensity physical activity for overweight patients?

    <p>30 minutes a day for most days of the week</p> Signup and view all the answers

    What is the primary objective of fish oil supplementation?

    <p>To reduce triglycerides and VLDL-C</p> Signup and view all the answers

    How do Bile Acid Resins (BARs) lower LDL levels?

    <p>By interrupting enterohepatic circulation of bile acids</p> Signup and view all the answers

    What are the common adverse effects of Bile Acid Resins (BARs)?

    <p>Constipation, bloating, nausea</p> Signup and view all the answers

    What are the objectives of dietary therapy in non-pharmacological treatment?

    <p>To progressively decrease intake of total fat, saturated fat, and cholesterol</p> Signup and view all the answers

    Substance P binds to the subtype neurokinin-1 (NK1 ) ______

    <p>receptors</p> Signup and view all the answers

    NK1 receptor antagonists are now available for use as an adjunct to dexamethasone and a 5HT3 antagonist in preventing nausea and ______ associated with moderately and highly emetogenic chemotherapy

    <p>vomiting</p> Signup and view all the answers

    A newer NK1 receptor antagonist netupitant is now available as a mixed-dose combination with palonosetron (a 5HT3 antagonist) known as NEPA for the prevention of acute and delayed nausea and ______ associated with moderately emetogenic chemotherapy and highly emetogenic cisplatin-based chemotherapy

    <p>vomiting</p> Signup and view all the answers

    NK1 receptor antagonists are inhibitors, and sometimes inducers, of cytochrome P450 (CYP3A4) and inducers of ______

    <p>CYP2C9</p> Signup and view all the answers

    Therefore, potential drug interactions with chemotherapeutic agents and other concomitantly administered agents, for example, ______, may occur

    <p>warfarin</p> Signup and view all the answers

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