Pharmacological Interactions and Hypertensive Crises
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Questions and Answers

What is the primary reason for administering multiple doses of activated charcoal in patients with glipizide overdose?

  • To accelerate the metabolism of glipizide in the liver
  • To reduce the risk of gastrointestinal bleeding
  • To enhance the absorption of glipizide in the gut
  • To counteract the effects of enterohepatic circulation (correct)

What is the mechanism by which multiple doses of activated charcoal can help in glipizide overdose?

  • By promoting the excretion of glipizide in the kidneys
  • By blocking the binding of glipizide to its receptors
  • By reducing the absorption of glipizide in the gut (correct)
  • By inhibiting the metabolism of glipizide in the liver

Why is glipizide more likely to cause prolonged hypoglycemic effects compared to other oral hypoglycemic agents?

  • Because it has a longer half-life
  • Because it is more lipophilic
  • Because it undergoes extensive first-pass metabolism
  • Because it has an enterohepatic circulation (correct)

What is the expected outcome of administering multiple doses of activated charcoal in patients with glipizide overdose?

<p>Reduced risk of hypoglycemic episodes (C)</p> Signup and view all the answers

What is the primary benefit of using activated charcoal in the management of glipizide overdose?

<p>Its ability to reduce the absorption of glipizide in the gut (A)</p> Signup and view all the answers

What should be avoided until the patient's mental status is fully restored?

<p>Giving medication by mouth (A)</p> Signup and view all the answers

When is it safe to administer oral medications to a patient?

<p>When the patient has fully regained mental status (C)</p> Signup and view all the answers

What is the primary consideration when deciding when to administer oral medications?

<p>The patient's level of consciousness (A)</p> Signup and view all the answers

Why is it important to wait until a patient has fully regained mental status before administering oral medications?

<p>To prevent aspiration or choking (D)</p> Signup and view all the answers

What is the most important factor in determining when to administer oral medications to a patient?

<p>The patient's level of consciousness (A)</p> Signup and view all the answers

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