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Questions and Answers
Which medication is associated with the term 'No'?
Which medication is associated with the term 'No'?
Which medication is known as 'Popular'?
Which medication is known as 'Popular'?
What is the medication associated with 'Meds'?
What is the medication associated with 'Meds'?
MAOIs can lead to _____, tremors, elevated temperature, and elevated blood pressure.
MAOIs can lead to _____, tremors, elevated temperature, and elevated blood pressure.
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Which foods should be avoided when taking MAOIs?
Which foods should be avoided when taking MAOIs?
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Which of the following medications should be avoided when taking MAOIs?
Which of the following medications should be avoided when taking MAOIs?
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What classification do MAOIs fall under?
What classification do MAOIs fall under?
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How do MAOIs exert their antidepressant effect?
How do MAOIs exert their antidepressant effect?
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MAOIs are used for patients who have had success with SSRIs.
MAOIs are used for patients who have had success with SSRIs.
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Which of the following are contraindications for MAOIs?
Which of the following are contraindications for MAOIs?
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What can be triggered by eating foods rich in tyramine while on MAOIs?
What can be triggered by eating foods rich in tyramine while on MAOIs?
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What are common side effects of MAOIs?
What are common side effects of MAOIs?
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Orthostatic hypotension can cause _____, dry mouth, and lethargy.
Orthostatic hypotension can cause _____, dry mouth, and lethargy.
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What should patients on MAOIs avoid?
What should patients on MAOIs avoid?
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What should a patient inform healthcare professionals about?
What should a patient inform healthcare professionals about?
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What should be assessed in patients taking MAOIs?
What should be assessed in patients taking MAOIs?
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Patients should avoid _____ rich foods that can lead to hypertensive crisis.
Patients should avoid _____ rich foods that can lead to hypertensive crisis.
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What should patients on MAOIs also avoid?
What should patients on MAOIs also avoid?
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Study Notes
Monoamine Oxidase Inhibitors (MAOIs)
- Nardil is a specific MAOI medication.
- Parnate is another well-known MAOI.
- Marplan represents a third option within the MAOI class.
Dietary Restrictions
- Consuming tyramine-rich foods such as avocados, cheese, wine, aged meats, and smoked fish is prohibited due to potential adverse reactions.
- Avoiding barbiturates, meperidine (Demerol), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs) is crucial for safety.
Drug Interactions
- Antihypertensives, over-the-counter drugs, cold remedies, asthma medications, and nasal decongestants should be avoided due to significant interactions.
Classification and Mechanism
- MAOIs are classified as antidepressants.
- They work by blocking monoamine oxidase, which increases the availability of norepinephrine and serotonin in nerve terminals, enhancing antidepressant effects.
Clinical Use
- MAOIs are primarily used for patients with depression who have not responded to other treatments like SSRIs.
Contraindications
- Patients with impaired renal or hepatic function and those with cardiovascular or cerebrovascular diseases should not use MAOIs.
Precautions
- A hypertensive crisis may occur from consuming tyramine-rich foods; awareness of this is essential.
- MAOIs can interact dangerously with various medications.
Side Effects
- Possible side effects include CNS stimulation, leading to anxiety, agitation, hypomania, or mania.
Additional Symptoms
- Orthostatic hypotension can manifest as headaches, dry mouth, or lethargy.
Nursing Implications
- Advise patients to steer clear of over-the-counter medications like cold remedies, nasal decongestants, and asthma treatments.
- Ensure patients inform all healthcare providers about their MAOI use to prevent complications.
- Regularly assess mood changes and evaluate for any suicidal tendencies.
- Determine if patients require assistance with dosing or are capable of self-dosing.
- Educate patients on avoiding tyramine-rich foods and additional items like chocolate and caffeinated beverages to mitigate risk of hypertensive crises.
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Description
This quiz provides an overview of Monoamine Oxidase Inhibitors (MAOIs), their dietary restrictions, drug interactions, classification, and mechanism of action. Explore the key MAOI medications like Nardil, Parnate, and Marplan, and understand their clinical applications in treating depression.
