Podcast
Questions and Answers
What is the potential benefit of alternate-day administration of corticosteroids?
What is the potential benefit of alternate-day administration of corticosteroids?
- Reducing the risk of infection
- Allowing the HPA axis to recover on days the hormone is not taken (correct)
- Increasing the absorption of calcium in the intestines
- Decreasing the production of sex hormones
What is the most common adverse effect of long-term glucocorticoid therapy?
What is the most common adverse effect of long-term glucocorticoid therapy?
- Cushing-like syndrome
- Osteoporosis (correct)
- Hypokalemia
- Hypertension
What is the consequence of sudden discontinuation of glucocorticosteroids in patients with suppression of the HPA axis?
What is the consequence of sudden discontinuation of glucocorticosteroids in patients with suppression of the HPA axis?
- Hypoglycemia
- Acute adrenal insufficiency (correct)
- Hypertension
- Emotional disturbances
Which drug is used to treat patients with Cushing syndrome?
Which drug is used to treat patients with Cushing syndrome?
What is the role of spironolactone in the treatment of hypertension?
What is the role of spironolactone in the treatment of hypertension?
Why is it necessary to taper the dose of glucocorticosteroids slowly during discontinuation?
Why is it necessary to taper the dose of glucocorticosteroids slowly during discontinuation?
What is the percentage of glucocorticoids bound to plasma proteins?
What is the percentage of glucocorticoids bound to plasma proteins?
What is the primary organ responsible for metabolizing corticosteroids?
What is the primary organ responsible for metabolizing corticosteroids?
Why is prednisone preferred in pregnancy?
Why is prednisone preferred in pregnancy?
What is the fate of corticosteroids after metabolism?
What is the fate of corticosteroids after metabolism?
What happens to the HPA axis when large doses of corticosteroids are required for more than 2 weeks?
What happens to the HPA axis when large doses of corticosteroids are required for more than 2 weeks?
What is the primary consideration when determining the dosage of corticosteroids?
What is the primary consideration when determining the dosage of corticosteroids?
