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Questions and Answers
What is the primary route of excretion for erythromycin?
What is the primary route of excretion for erythromycin?
- Feces
- Urine
- Bile (correct)
- Sweat
Which of the following is a key pharmacokinetic advantage of clarithromycin over erythromycin?
Which of the following is a key pharmacokinetic advantage of clarithromycin over erythromycin?
- Lower incidence of gastrointestinal side effects (correct)
- Better acid stability
- Longer half-life
- Higher CSF penetration
Which of the following pathogens is azithromycin particularly effective against?
Which of the following pathogens is azithromycin particularly effective against?
- Anaerobic bacteria
- Chlamydia species (correct)
- Gram-positive bacteria
- Gram-negative bacteria
What is the primary mechanism of action for macrolide antibiotics like erythromycin?
What is the primary mechanism of action for macrolide antibiotics like erythromycin?
Which of the following is a common adverse effect associated with macrolide antibiotics?
Which of the following is a common adverse effect associated with macrolide antibiotics?
Which of the following is a key therapeutic use of erythromycin?
Which of the following is a key therapeutic use of erythromycin?
Which of the following is NOT a common adverse effect associated with macrolide antibiotics?
Which of the following is NOT a common adverse effect associated with macrolide antibiotics?
Which macrolide antibiotic has the broadest spectrum of activity against Gram-positive and Gram-negative organisms?
Which macrolide antibiotic has the broadest spectrum of activity against Gram-positive and Gram-negative organisms?
What is the primary mechanism of action for macrolide antibiotics?
What is the primary mechanism of action for macrolide antibiotics?
Which of the following is NOT a common clinical use for macrolide antibiotics?
Which of the following is NOT a common clinical use for macrolide antibiotics?
What is the primary reason for the development of resistance to erythromycin, a macrolide antibiotic?
What is the primary reason for the development of resistance to erythromycin, a macrolide antibiotic?
Which adverse effect is associated with the use of macrolide antibiotics in newborn infants?
Which adverse effect is associated with the use of macrolide antibiotics in newborn infants?
Which of the following best describes the pharmacokinetics of macrolides?
Which of the following best describes the pharmacokinetics of macrolides?
What is a common side effect associated with macrolides?
What is a common side effect associated with macrolides?
Which macrolide is specifically active against penicillin- and erythromycin-resistant Streptococcus pneumoniae?
Which macrolide is specifically active against penicillin- and erythromycin-resistant Streptococcus pneumoniae?
What is the mechanism of action of clindamycin?
What is the mechanism of action of clindamycin?
Which macrolide is known to cause prolongation of the QT interval?
Which macrolide is known to cause prolongation of the QT interval?
What distinguishes ketolides like telithromycin from other macrolides?
What distinguishes ketolides like telithromycin from other macrolides?