Pharmaceutical Tablets and Capsules

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Questions and Answers

Which test evaluates the uniformity of drug content among different tablets within a batch?

  • Content uniformity test (correct)
  • Disintegration test
  • Friability test
  • Dissolution test

Which of the following tablet defects is characterized by the separation of a tablet into two or more distinct layers?

  • Chipping
  • Sticking
  • Picking
  • Capping (correct)

What role do disintegrants play in tablet formulations?

  • Facilitate the breakdown of the tablet into smaller fragments (correct)
  • Promote the adhesion of tablet ingredients
  • Enhance the sweetness of the tablet
  • Control the release rate of the drug

Which type of tablet coating is commonly used to protect drugs that are unstable in the acidic environment of the stomach?

<p>Enteric coating (D)</p> Signup and view all the answers

What is the primary function of gelatin in the production of soft gelatin capsules?

<p>To form the capsule shell (A)</p> Signup and view all the answers

In a matrix tablet system, what is the role of the matrix material?

<p>To control the release rate of the drug (B)</p> Signup and view all the answers

Which type of capsule is typically used for delivering dry powder formulations?

<p>Hard gelatin capsules (A)</p> Signup and view all the answers

What is the purpose of using glycerin in the gelatin formulation for capsule production?

<p>To plasticize the gelatin and provide flexibility (A)</p> Signup and view all the answers

Which type of tablet compression machine is known for its high-speed production capability?

<p>Rotary tablet machine (C)</p> Signup and view all the answers

What is the primary function of a Rotosort machine in pharmaceutical manufacturing?

<p>To inspect and sort tablets or capsules (A)</p> Signup and view all the answers

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Flashcards

Tablet Testing

Tests to evaluate the physical and chemical properties of tablets, ensuring quality and performance.

Tablet Coating Equipment

Equipment used to apply a coating to tablets, such as pan coaters and fluid bed coaters.

Tablet Defects

Undesirable attributes in tablets, like chipping, cracking, or variations in color or size due to manufacturing issues.

Pharmaceutical Excipients

Inactive ingredients added to tablet formulations to enhance properties like binding, disintegration, or flow.

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Capsules

Solid dosage forms in which the drug substance and excipients are enclosed within a soluble shell.

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Matrix Tablet System

Tablets that release the drug slowly over time due to a matrix of insoluble material.

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Tablet Compression Machines

Machines that compress powder into tablets, varying in speed and design.

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Suppositories and Pessaries

Dosage forms designed for insertion into the rectum or vagina to deliver medication.

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Rotosort

A machine or process to check and sort tablets and capsules.

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Stages in Tablet Production

The series of steps involved in producing tablets, from weighing raw materials to packaging the final product.

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Study Notes

  • Tablets undergo specific tests to ensure quality and efficacy.
  • Various equipment are employed to conduct these tests on tablets.
  • Tablet defects can arise from different causes during manufacturing.
  • Pharmaceutical excipients are categorized into classes, each with examples.
  • Tablet coating is performed using specialized equipment.
  • Different types of resins are utilized for tablet coating, along with examples.
  • Gelatin capsules have shells composed of specific materials.
  • Matrix tablet systems exist in different types.
  • Capsules come in various types.
  • Gelatin-glycerin formulations are used in capsule production in specific ratios.
  • Tablets are available in multiple types.
  • Tablet compression is achieved using different types of machines.
  • Rotosort is a machine used in pharmaceutical manufacturing.
  • Suppositories and pessaries are distinct dosage forms.
  • Tablet production involves several stages.
  • Capsule production also includes multiple stages.
  • RotoFIL and other filling machines are used in pharmaceutical manufacturing.

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