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Questions and Answers
What is the definition of New Molecular Entity (NME) according to the FDA?
What is the definition of New Molecular Entity (NME) according to the FDA?
- A drug isolated from plants
- A drug that has undergone molecular modification
- A drug that has undergone organic synthesis
- An active ingredient that has never before been marketed in the US (correct)
What is the purpose of excipients in a dosage form?
What is the purpose of excipients in a dosage form?
- To undergo pre-clinical studies
- To produce the pharmacological activity
- To conceal offensive taste and protect from environmental influence (correct)
- To isolate the drug from plants
What is the role of Drug Delivery System in drug administration?
What is the role of Drug Delivery System in drug administration?
- To isolate the drug from plants
- To provide a mechanism for safe and convenient drug delivery (correct)
- To produce the pharmacological activity
- To undergo investigational new drug clinical trials
What is the main characteristic of a finished dosage form?
What is the main characteristic of a finished dosage form?
What is a key advantage of liquid dosage form solutions?
What is a key advantage of liquid dosage form solutions?
What is a general rule in preparing solutions?
What is a general rule in preparing solutions?
What is the purpose of Bacteriostatic Water for Injection (BWI)?
What is the purpose of Bacteriostatic Water for Injection (BWI)?
What is the main difference between Water for Injection and Sterile Water for Injection?
What is the main difference between Water for Injection and Sterile Water for Injection?
What is the purpose of adding the aqueous solution to the alcoholic solution when using an alcoholic solution of a purely water-soluble drug?
What is the purpose of adding the aqueous solution to the alcoholic solution when using an alcoholic solution of a purely water-soluble drug?
What is the suitable pH range for Purified Water used in prescription and manufactured finished products?
What is the suitable pH range for Purified Water used in prescription and manufactured finished products?
When adding salt to syrup, what is the recommended initial step?
When adding salt to syrup, what is the recommended initial step?
What is the definition of an orphan drug?
What is the definition of an orphan drug?
What is the difference between in vitro and in vivo tests?
What is the difference between in vitro and in vivo tests?
What are granules in relation to powder dosage forms?
What are granules in relation to powder dosage forms?
What is the purpose of using a mortar and pestle in pharmaceutical preparation?
What is the purpose of using a mortar and pestle in pharmaceutical preparation?
What does a treatment IND permit?
What does a treatment IND permit?
What is the content of the Papyrus Ebers?
What is the content of the Papyrus Ebers?
Which method is NOT used in the manufacture of tablets?
Which method is NOT used in the manufacture of tablets?
What is the primary component of gelatin capsules?
What is the primary component of gelatin capsules?
Which method is NOT utilized in transdermal drug delivery systems (TDDS)?
Which method is NOT utilized in transdermal drug delivery systems (TDDS)?
What is a commonly used base for rectal suppositories?
What is a commonly used base for rectal suppositories?
What is the ratio of citric acid monohydrate to tartaric acid in effervescent powders?
What is the ratio of citric acid monohydrate to tartaric acid in effervescent powders?
Which of the following is NOT a type of tablet?
Which of the following is NOT a type of tablet?
What are the criteria for satisfactory suppository bases?
What are the criteria for satisfactory suppository bases?
Which of the following best describes the purpose of a drug delivery system?
Which of the following best describes the purpose of a drug delivery system?
What is the primary role of finished dosage forms?
What is the primary role of finished dosage forms?
Which phase of clinical trials involves long-term animal toxicity studies?
Which phase of clinical trials involves long-term animal toxicity studies?
What is the main purpose of a dosage form?
What is the main purpose of a dosage form?
What is the primary function of a lead compound in drug development?
What is the primary function of a lead compound in drug development?
What is the primary purpose of a treatment IND?
What is the primary purpose of a treatment IND?
What are granules in relation to powder dosage forms?
What are granules in relation to powder dosage forms?
What is the primary purpose of using a mortar and pestle in pharmaceutical preparation?
What is the primary purpose of using a mortar and pestle in pharmaceutical preparation?
What is the purpose of automatic devices for self-injecting drugs like Valium?
What is the purpose of automatic devices for self-injecting drugs like Valium?
What is the primary use of Selsun Blue?
What is the primary use of Selsun Blue?
What is the primary function of Sterile Water for Injection?
What is the primary function of Sterile Water for Injection?
What is the main characteristic of Bacteriostatic Water for Injection?
What is the main characteristic of Bacteriostatic Water for Injection?
What is the primary advantage of using a liquid dosage form solution?
What is the primary advantage of using a liquid dosage form solution?
What is the role of Water for Injection in pharmaceutical preparations?
What is the role of Water for Injection in pharmaceutical preparations?
What is the purpose of using the salt form of the drug in preparing solutions?
What is the purpose of using the salt form of the drug in preparing solutions?
What defines Purified Water used in prescription and manufactured finished products?
What defines Purified Water used in prescription and manufactured finished products?
What is the primary function of effervescent powders?
What is the primary function of effervescent powders?
What is the primary component of gelatin capsules?
What is the primary component of gelatin capsules?
What is the primary function of suppositories as a solid dosage form?
What is the primary function of suppositories as a solid dosage form?
What is the primary source of collagen for making gelatin capsules?
What is the primary source of collagen for making gelatin capsules?
Which method is NOT utilized in the manufacture of tablets?
Which method is NOT utilized in the manufacture of tablets?
What is the primary purpose of transdermal drug delivery systems (TDDS)?
What is the primary purpose of transdermal drug delivery systems (TDDS)?
What is a key characteristic of suppositories as a solid dosage form?
What is a key characteristic of suppositories as a solid dosage form?
Which criterion is NOT considered for satisfactory suppository bases?
Which criterion is NOT considered for satisfactory suppository bases?
Study Notes
Pharmaceutical Dosage Forms and Delivery Systems Overview
- Effervescent powders use citric acid monohydrate and tartaric acid in a 1:2 ratio, reacting with sodium bicarbonate to produce CO2.
- Gelatin capsules are made from collagen, obtained from animal skin, connective tissues, and bones, with different types and sizes available.
- Tablets are solid dosage forms primarily prepared by compression, offering advantages such as low manufacturing cost and easy swallowability, but may have limitations with certain drugs.
- Various methods of tablet manufacture include dry granulation, wet granulation, fluid bed processing, direct compression, and multiple-layered tablets.
- Different types of tablets, such as chewable, buccal, effervescent, sugar-coated, film-coated, and enteric-coated, cater to specific needs and preferences.
- Transdermal drug delivery systems (TDDS) utilize methods like electroporation, iontophoresis, phonophoresis, and high-velocity powder particles to enhance drug diffusion through the skin.
- Other solid dosage forms include lozenges, hypodermic tablets, pellets, cataplasm, plasters, transdermal patches, pills, bolus, dressing, and lollipops.
- Review questions cover topics ranging from the capacity of Capsule No.4 to the method of preparing hard gelatin capsules.
- TDDS enhanced by the application of short, high-voltage electric pulses, and other methods like iontophoresis and phonophoresis are used to facilitate drug diffusion.
- Suppositories, including rectal, vaginal, and urethral types, are solid dosage forms intended for insertion into body orifices, useful in specific patient populations.
- Criteria for satisfactory suppository bases include inertness, firmness, and rapid dissolution, with bases like fatty/oleaginous, water-soluble, and miscellaneous meeting these criteria.
- Cocoa butter is a good base for rectal suppositories, melting just below body temperature and maintaining solidity at room temperature. Different methods are used to prepare suppository bases, such as hand-rolling, compression, and fusion method.
Pharmaceutical Dosage Forms and Delivery Systems Overview
- Effervescent powders use citric acid monohydrate and tartaric acid in a 1:2 ratio, reacting with sodium bicarbonate to produce CO2.
- Gelatin capsules are made from collagen, obtained from animal skin, connective tissues, and bones, with different types and sizes available.
- Tablets are solid dosage forms primarily prepared by compression, offering advantages such as low manufacturing cost and easy swallowability, but may have limitations with certain drugs.
- Various methods of tablet manufacture include dry granulation, wet granulation, fluid bed processing, direct compression, and multiple-layered tablets.
- Different types of tablets, such as chewable, buccal, effervescent, sugar-coated, film-coated, and enteric-coated, cater to specific needs and preferences.
- Transdermal drug delivery systems (TDDS) utilize methods like electroporation, iontophoresis, phonophoresis, and high-velocity powder particles to enhance drug diffusion through the skin.
- Other solid dosage forms include lozenges, hypodermic tablets, pellets, cataplasm, plasters, transdermal patches, pills, bolus, dressing, and lollipops.
- Review questions cover topics ranging from the capacity of Capsule No.4 to the method of preparing hard gelatin capsules.
- TDDS enhanced by the application of short, high-voltage electric pulses, and other methods like iontophoresis and phonophoresis are used to facilitate drug diffusion.
- Suppositories, including rectal, vaginal, and urethral types, are solid dosage forms intended for insertion into body orifices, useful in specific patient populations.
- Criteria for satisfactory suppository bases include inertness, firmness, and rapid dissolution, with bases like fatty/oleaginous, water-soluble, and miscellaneous meeting these criteria.
- Cocoa butter is a good base for rectal suppositories, melting just below body temperature and maintaining solidity at room temperature. Different methods are used to prepare suppository bases, such as hand-rolling, compression, and fusion method.
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Description
Test your knowledge of pharmaceutical dosage forms and delivery systems with this overview quiz. Explore topics like tablet manufacture methods, types of tablets, transdermal drug delivery, and suppository bases. Perfect for pharmacy students and professionals looking to expand their understanding of pharmaceutical preparations.