Solid Dosage Forms Overview Quiz

Tablet Types and Characteristics

• Orally disintegrating tablets (ODTs) are designed to provide rapid disintegration and rapid drug release.
• Conventional compressed tablets are characterized by rapid release of the active ingredient.
• Modified-release tablets are designed to release drug slowly and continuously over an extended period of time.

Tablet Design and Function

• The indentation running down the middle of many caplets is called a "break-line" or "score line", which facilitates easy breaking of the tablet into two halves.
• Multiple compressed tablets offer the advantage of flexibility in dosage adjustment.

Quality Attributes and Textbook

• The quality attributes of tablets mentioned in the text are: strength, uniformity, and purity.
• The recommended textbook for this course is not specified.
• By the end of the course, the student should be able to design, prepare, and evaluate solid dosage forms.

Tablet Definition and Function

• According to the European Pharmacopoeia (5th edition, 2005), tablets are defined as "solid preparations with or without coatings, consisting of a mixture of active substances and excipients, usually in a specific ratio, which are obtained by compressing the mixture".
• The original definition of a pill is a small, round, solid dosage form, made from a mixture of active ingredients and excipients.
• The primary function of excipients in tablet formulation is to enhance the performance of the active ingredient.

Solid Dosage Forms

• The main difference between powders and granules in the context of solid dosage forms is that granules are aggregated powders with a larger particle size.
• The main disadvantage of tablets as a dosage form is that they can be difficult to swallow, especially for pediatric and geriatric patients.
• Bioavailability is a crucial factor in modifying the bioavailability of drugs from different dosage forms.