Podcast
Questions and Answers
What is the main reason for formulating drugs with very low solubility as suspensions?
What is the main reason for formulating drugs with very low solubility as suspensions?
- To mask the unpleasant taste of the drug
- To control the drug's release rate
- To make the drug easier to swallow (correct)
- To improve the stability of the drug
What is a key disadvantage of suspensions?
What is a key disadvantage of suspensions?
- They are not aesthetically pleasing
- They are difficult to formulate
- They have a high rate of sedimentation
- They are bulky and difficult for patients to carry (correct)
What is the main factor that contributes to the physical instability of pharmaceutical suspensions?
What is the main factor that contributes to the physical instability of pharmaceutical suspensions?
- Sedimentation of the dispersed phase
- Particle-particle interactions (correct)
- Adsorption of ions onto the particle surface
- Ionization of functional groups on the drug
How does the adsorption of ions onto the surface of drug particles in a suspension affect the physical stability?
How does the adsorption of ions onto the surface of drug particles in a suspension affect the physical stability?
What is the purpose of formulating drugs with an unpleasant taste as insoluble derivatives?
What is the purpose of formulating drugs with an unpleasant taste as insoluble derivatives?
What is the characteristic particle size range of colloidal systems in pharmaceutical suspensions?
What is the characteristic particle size range of colloidal systems in pharmaceutical suspensions?
Which of the following is a main aim of the formulation scientist when dealing with pharmaceutical suspensions?
Which of the following is a main aim of the formulation scientist when dealing with pharmaceutical suspensions?
What kind of system is a pharmaceutical suspension classified as?
What kind of system is a pharmaceutical suspension classified as?
In what form are drug particles in a stable pharmaceutical suspension after agitation?
In what form are drug particles in a stable pharmaceutical suspension after agitation?
Which of the following is NOT a common route of administration for pharmaceutical suspensions?
Which of the following is NOT a common route of administration for pharmaceutical suspensions?