5 Questions
What is a pharmaceutical suspension?
A coarse dispersion with internal phase dispersed uniformly throughout the external phase
Which type of suspension may have an organic or oily liquid as the external phase?
Non-oral suspension
What is the proportion of solid particles in a concentrated suspension?
50% w/v solid
Which type of suspension is used for insoluble or poorly soluble drugs required to be given orally?
Oral suspension
What advantage does a pharmaceutical suspension offer for certain drugs in aqueous solution?
Reduce the contact time between solid drug particles and dispersion media to increase stability
Study Notes
Pharmaceutical Suspensions
- A pharmaceutical suspension is a type of dosage form consisting of insoluble solid particles dispersed in a liquid vehicle.
Types of Suspensions
- One type of suspension may have an organic or oily liquid as the external phase.
Concentrated Suspensions
- In a concentrated suspension, the proportion of solid particles is typically high, usually above 20%.
Insoluble or Poorly Soluble Drugs
- Suspensions are often used for insoluble or poorly soluble drugs that need to be administered orally.
Advantages of Suspensions
- Pharmaceutical suspensions offer an advantage for certain drugs in aqueous solution, as they can improve the bioavailability and stability of the active pharmaceutical ingredient.
This lecture covers the definition and composition of pharmaceutical suspensions, including the dispersion of insoluble solid particles in a liquid medium. It also discusses the use of suspending agents and the characteristics of the external phase.
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