Pharmaceutical Suspensions Overview

<p>The propellant. (B)</p> Signup and view all the answers

<p>Consumer brands' popularity. (D)</p> Signup and view all the answers

<p>Rapid volatilization of the propellant. (D)</p> Signup and view all the answers

<p>It could control the physical form and particle size of the emitted product. (B)</p> Signup and view all the answers

<p>Glass. (B)</p> Signup and view all the answers

<p>Aluminum Hydroxide Gel (A)</p> Signup and view all the answers

<p>To provide pressure for dispensing the contents (D)</p> Signup and view all the answers

<p>The physical delivery of medication (B)</p> Signup and view all the answers

<p>Easy withdrawal of medication without contaminating the rest (A)</p> Signup and view all the answers

<p>A variety of forms including fine mist or steady stream (D)</p> Signup and view all the answers

<p>To maintain the efficacy of active ingredients over time (B)</p> Signup and view all the answers

<p>They are unaffected by storage conditions (D)</p> Signup and view all the answers

<p>It controls how the medication is expelled and its form (D)</p> Signup and view all the answers

<p>It activates the valve assembly for product emission. (A)</p> Signup and view all the answers

<p>The spring (D)</p> Signup and view all the answers

<p>They maintain semisolid form for prolonged contact. (C)</p> Signup and view all the answers

<p>They must be sterile. (D)</p> Signup and view all the answers

<p>The inner dimensions of the dip tube and housing. (D)</p> Signup and view all the answers

<p>An emulsion dosage form. (A)</p> Signup and view all the answers

<p>Stability is enhanced when the propellant is in the internal phase. (C)</p> Signup and view all the answers

<p>It must receive the same consideration as the container's inner part. (B)</p> Signup and view all the answers

Aerosol containers protect medicinal agents from oxygen, moisture, and light, preserving their efficacy during use and shelf life.

Aerosols apply topical medications in a thin, uniform layer to the skin, often reducing irritation compared to fingertip application, and providing a cooling effect.

Aerosol formulations consist of a product concentrate (active ingredient + adjuncts) and a propellant (liquefied gas or compressed gas).

Propellants can be liquefied gases or mixtures, frequently serving as a solvent and vehicle for the product concentrate. Compressed gases (e.g., CO2) can also be used as propellants.

Aerosol containers are made from various materials, including glass (coated or uncoated), metal (tin-plated steel, aluminum, stainless steel), and plastics.

Container selection for aerosols depends on its ability to handle intended pressure, compatibility with product components, production methods, design appeal, and cost.

The typical aerosol valve assembly includes parts that control the physical form and particle size of the emitted product (e.g., metered valves for controlling dosage).

Proper formulation and valve control ensure controlled physical form (e.g., mist, spray) and particle size, improving drug efficacy, while allowing controlled dosage.

A two-phase gel usually composed of non-organic compounds.

A single-phase gel usually composed of organic compounds.

Gels that absorb large amounts of water, often composed of polymers.

Gels containing hydrocarbons, fats, or greasy materials.

A pressurized dosage form that emits a fine dispersion of liquids or solids in a gas.

A liquefied or gaseous substance that provides pressure to propel the contents of an aerosol container.

Aerosols can deliver contents as a mist, spray, stream, foam, etc.

Easy withdrawal of medication without contamination; preservation of remaining material in the aerosol.

The button you press on an aerosol can to release the product. It opens and closes the valve, letting the product out through a small opening.

The stem supports the actuator and guides the product to the release point. It helps control the form of the product as it comes out.

A seal placed between the stem and the actuator. It stops the product from leaking when the valve is closed.

It holds the gasket in place and pushes the actuator back when you release the pressure, closing the valve.

It attaches the valve to the aerosol can and holds it in place. Since it touches the product, it needs to be compatible with the formulation.

It connects the stem, actuator, and dip tube. Along with the stem, it helps control the delivery rate and form of the product.

It carries the product from the container to the valve. Its size depends on the product's viscosity and desired delivery rate.

A fluffy, semi-solid dosage form that contains tiny gas bubbles dispersed in a liquid. It's often used for topical applications.