parenteral in Pharmaceutical 3

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What is the meaning of the term 'parenteral'?

Injectable route of administration (correct)

Metabolism of microorganisms

Inside the intestine

Oral route of administration

What is the origin of the term 'parenteral'?

Latin words Para and Enteron

Chinese words for outside and inside

Greek words Para and Enteron (correct)

Arabic words for injection and digestion

What does the parenteral route of administration bypass?

Lipid polysaccharide products

Fever producing substances

Oral route of administration (correct)

Pyrogens

Parenteral route of administration involves injecting drugs outside the intestines.

True Signup and view all the answers

The parenteral route of administration bypasses the Pyrogens.

True Signup and view all the answers

The parenteral route of administration only involves soluble fever producing substances.

False Signup and view all the answers

When was the first historical reference to the parenteral administration of a compound?

Late 15th century Signup and view all the answers

What led to a ban in the use of parenteral medical treatment for several centuries?

Death of all involved individuals Signup and view all the answers

When did the development of the hypodermic needle and the use of parenterally injected drugs in humans first occur?

Mid 19th century Signup and view all the answers

What was produced by Baxter in 1931, marking an important milestone in the history of parenteral administration?

First commercially prepared intravenous solutions Signup and view all the answers

In the mid 1960s, what service did many hospitals introduce?

Intravenous admixture services Signup and view all the answers

What type of preparations are parenteral preparations?

Sterile and pyrogen free liquids Signup and view all the answers

In which parts of the body are parenteral drugs administered?

Directly into the veins, muscles or under the skin Signup and view all the answers

What is an important requirement for parenteral drugs to circumvent the body's first line defense?

Free from microbial contamination Signup and view all the answers

Which of the following preparations require special formulation and may not comply with certain parts of the monograph?

All parenteral preparations Signup and view all the answers

What is a key feature of parenteral drugs' dosage form for administration?

Conveying a drug through skin or mucous membranes Signup and view all the answers

When is the parenteral route of administration preferred?

When the drug is ineffective by other routes Signup and view all the answers

What is a key reason for using the parenteral route of administration?

To bypass the body's first line defense Signup and view all the answers

What is the purpose of using excipients in parenteral preparations?

To enhance the stability and bioavailability of the active ingredient(s) Signup and view all the answers

What is the recommended quality for water used as a vehicle for aqueous injections?

Freshly distilled and free from carbon dioxide Signup and view all the answers

Under what conditions can sterilization at the initial stage of production be omitted?

When the solution or preparation is immediately sterilized upon finalization Signup and view all the answers

What might be added to an aqueous solution for injection to render it isotonic?

Sodium chloride or other suitable substance(s) Signup and view all the answers

What is the purpose of using antimicrobial preservatives in parenteral preparations?

To prevent microbial contamination and ensure safety Signup and view all the answers

Excipients should be added in large quantities to ensure stability and efficacy of parenteral preparations.

False Signup and view all the answers

Water for injections should be free from carbon dioxide and comply with Test for bacterial endotoxins.

True Signup and view all the answers

Sterilization at the initial stage of production may be omitted for aqueous injections.

True Signup and view all the answers

Sodium chloride may not be added to an aqueous solution for injection to render it isotonic.

False Signup and view all the answers

The parenteral route of administration only involves soluble fever-producing substances.

False Signup and view all the answers

What is the purpose of using excipients in parenteral preparations?

To make the preparation isotonic with blood Signup and view all the answers

What might be added to an aqueous solution for injection to render it isotonic?

Sodium chloride or other suitable substance(s) Signup and view all the answers

What is a key requirement for water used as a vehicle for aqueous injections?

It should comply with Test for bacterial endotoxins Signup and view all the answers

Under what conditions can sterilization at the initial stage of production be omitted?

If it is immediately sterilized upon finalization Signup and view all the answers

What should excipients used in parenteral preparations NOT do?

Increase the bioavailability of the active ingredient Signup and view all the answers

What is the purpose of using antimicrobial preservatives in parenteral preparations?

To prevent the growth of microorganisms in the preparation Signup and view all the answers

Which of the following Based On State Of Product According to USP (SVP) is corrrect :

All of the above Signup and view all the answers

which of the following classification of parenteral based of volume is correct :

A + B Signup and view all the answers

Parenteral preparations must be free of microorganisms. (True/False)

True Signup and view all the answers

Parenterals are prepared using aseptic techniques and special clothing. (True/False)

True Signup and view all the answers

Sodium chloride may be added to an aqueous solution for injection to render it isotonic. (True/False)

False Signup and view all the answers

Parenterals are administered through the intestines. (True/False)

False Signup and view all the answers

What is a key advantage of the intravenous (IV) route of administration?

It provides higher concentration of drugs to the bloodstream or tissues Signup and view all the answers

Why is the IV route of administration preferred in emergency situations?

It can provide fluids, electrolytes, and nutrition to patients with GI tract problems Signup and view all the answers

What type of patients can benefit from the IV route of administration?

Patients who cannot take food or have serious problems with the GI tract Signup and view all the answers

What is a key advantage of self-delivery of drugs via subcutaneous injections?

Targeted drug delivery Signup and view all the answers

When might injection of drugs directly into a tissue be preferred?

For drugs that require a rapid onset of action Signup and view all the answers

Parenteral drugs can be administered subcutaneously for sustained drug delivery. (True/False)

True Signup and view all the answers

Drugs that are inactivated in the gastrointestinal tract may be suitable for parenteral administration. (True/False)

True Signup and view all the answers

Antimicrobial preservatives are commonly used in parenteral preparations. (True/False)

True Signup and view all the answers

Parenteral drugs must be free of microorganisms. (True/False)

True Signup and view all the answers

parenteral in Pharmaceutical 3

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Questions and Answers

What is the meaning of the term 'parenteral'?

What is the origin of the term 'parenteral'?

What does the parenteral route of administration bypass?

Parenteral route of administration involves injecting drugs outside the intestines.

The parenteral route of administration bypasses the Pyrogens.

The parenteral route of administration only involves soluble fever producing substances.

When was the first historical reference to the parenteral administration of a compound?

What led to a ban in the use of parenteral medical treatment for several centuries?

When did the development of the hypodermic needle and the use of parenterally injected drugs in humans first occur?

What was produced by Baxter in 1931, marking an important milestone in the history of parenteral administration?

In the mid 1960s, what service did many hospitals introduce?

What type of preparations are parenteral preparations?

In which parts of the body are parenteral drugs administered?

What is an important requirement for parenteral drugs to circumvent the body's first line defense?

Which of the following preparations require special formulation and may not comply with certain parts of the monograph?

What is a key feature of parenteral drugs' dosage form for administration?

When is the parenteral route of administration preferred?

What is a key reason for using the parenteral route of administration?

What is the purpose of using excipients in parenteral preparations?

What is the recommended quality for water used as a vehicle for aqueous injections?

Under what conditions can sterilization at the initial stage of production be omitted?

What might be added to an aqueous solution for injection to render it isotonic?

What is the purpose of using antimicrobial preservatives in parenteral preparations?

Excipients should be added in large quantities to ensure stability and efficacy of parenteral preparations.

Water for injections should be free from carbon dioxide and comply with Test for bacterial endotoxins.

Sterilization at the initial stage of production may be omitted for aqueous injections.

Sodium chloride may not be added to an aqueous solution for injection to render it isotonic.

The parenteral route of administration only involves soluble fever-producing substances.

What is the purpose of using excipients in parenteral preparations?

What might be added to an aqueous solution for injection to render it isotonic?

What is a key requirement for water used as a vehicle for aqueous injections?

Under what conditions can sterilization at the initial stage of production be omitted?

What should excipients used in parenteral preparations NOT do?

What is the purpose of using antimicrobial preservatives in parenteral preparations?

Which of the following Based On State Of Product According to USP (SVP) is corrrect :

which of the following classification of parenteral based of volume is correct :

Parenteral preparations must be free of microorganisms. (True/False)

Parenterals are prepared using aseptic techniques and special clothing. (True/False)

Sodium chloride may be added to an aqueous solution for injection to render it isotonic. (True/False)

Parenterals are administered through the intestines. (True/False)

What is a key advantage of the intravenous (IV) route of administration?

Why is the IV route of administration preferred in emergency situations?

What type of patients can benefit from the IV route of administration?

What is a key advantage of self-delivery of drugs via subcutaneous injections?

When might injection of drugs directly into a tissue be preferred?

Parenteral drugs can be administered subcutaneously for sustained drug delivery. (True/False)

Drugs that are inactivated in the gastrointestinal tract may be suitable for parenteral administration. (True/False)

Antimicrobial preservatives are commonly used in parenteral preparations. (True/False)

Parenteral drugs must be free of microorganisms. (True/False)

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