Pharmaceutical Solutions Quiz

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Questions and Answers

What is the primary reason for choosing a suitable solvent in pharmaceutical solutions?

  • To improve the palatability of the solution.
  • To enhance the color of the solution.
  • To ensure the solubility of active ingredients. (correct)
  • To increase the viscosity of the preparation.

Which of the following is NOT a classification of pharmaceutical solutions based on usage?

  • Otic
  • Glycerin (correct)
  • Oral
  • Topical

What is the maximum allowed alcohol content in OTC oral products for children under 6 years old?

  • 10%
  • 0.5% (correct)
  • 5%
  • 2%

What type of mixture is formed when alcohol is combined with water?

<p>Hydroalcoholic mixture (D)</p> Signup and view all the answers

Which of the following solvents is considered toxic and should be completely removed before final formulation?

<p>Isopropyl alcohol (D)</p> Signup and view all the answers

What is one function of flavorings in medicinal solutions?

<p>To make the solution more palatable (C)</p> Signup and view all the answers

Why are some medicinal agents formulated as dry mixtures for solution?

<p>To improve stability in aqueous solutions (A)</p> Signup and view all the answers

What purpose do non-medicated syrups serve in extemporaneous compounding?

<p>To act as a pleasant-tasting vehicle for administering medications (A)</p> Signup and view all the answers

When preparing medicated syrups, what must be considered regarding drug compatibility?

<p>The acidity, basicity, or neutrality of the syrup (D)</p> Signup and view all the answers

What is the main role of sugar or sugar substitutes in syrup formulations?

<p>To enhance sweetness and viscosity (D)</p> Signup and view all the answers

What is the typical stability duration for solutions after reconstitution from dry mixtures?

<p>7-14 days (A)</p> Signup and view all the answers

Which type of common medicated syrups is primarily used to treat coughs?

<p>Antitussive syrups (C)</p> Signup and view all the answers

What is the primary purpose of alcohol content in tinctures?

<p>To preserve the tinctures (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of topical solutions?

<p>They provide systemic absorption (B)</p> Signup and view all the answers

What method is often used to prepare chemical tinctures?

<p>Dissolving the chemical substance in a solvent (D)</p> Signup and view all the answers

Which of the following indicates a proper storage method for tinctures?

<p>Tightly stoppered and protected from excessive temperatures (B)</p> Signup and view all the answers

Which ingredient is commonly considered a co-solvent in tinctures?

<p>Glycerin (C)</p> Signup and view all the answers

What type of solution is indicated for treatments of the throat and mouth?

<p>Aqueous solutions in concentrated form (C)</p> Signup and view all the answers

Which of the following substances is commonly included in oral solutions for medicinal purposes?

<p>Benzocaine (C)</p> Signup and view all the answers

What is the main intended use of vaginal douches?

<p>For irrigation and cleansing of the vagina (A)</p> Signup and view all the answers

Which of the following statements about oral solutions is true?

<p>They contain dissolved medicaments for oral use. (A)</p> Signup and view all the answers

What is the primary role of sucrose in syrup formulations?

<p>To impart viscosity and sweetness (B)</p> Signup and view all the answers

Which of the following is true regarding non-glycogenetic materials used in syrups?

<p>They provide similar viscosity as sucrose (A)</p> Signup and view all the answers

What is the typical sucrose concentration in most syrups for the desired properties?

<p>60-80% (C)</p> Signup and view all the answers

Why might alternative sweeteners like sorbitol or glycerin be preferred?

<p>They are beneficial for diabetic and sugar-restricted patients (A)</p> Signup and view all the answers

What is a characteristic of a properly prepared syrup containing sucrose?

<p>Inherently stable and growth-resistant (D)</p> Signup and view all the answers

What happens to the viscosity of syrup when sucrose is diluted?

<p>It decreases significantly (B)</p> Signup and view all the answers

What is a potential benefit of using thickeners in syrup formulations?

<p>To stabilize the syrup and maintain viscosity (A)</p> Signup and view all the answers

Why might synchronous agents be included in syrup formulations?

<p>To ensure complete solubility of ingredients (C)</p> Signup and view all the answers

Which of the following statements about thickening agents is false?

<p>They are only used in sucrose-based syrups. (D)</p> Signup and view all the answers

Flashcards

Solutions in Pharmacy

A mixture of solute and solvent, like a solid dissolved in a liquid, solid in a solid, or solid in a gas. In pharmacy, it's a liquid preparation with one or more dissolved chemical substances.

Types of Pharmaceutical Solutions

Solutions are classified based on how they're used, like for swallowing, ear drops, eye drops, or applying on the skin. They can also be classified based on what ingredients they have, like syrups, elixirs, spirits, and tinctures.

Advantages of Pharmaceutical Solutions

Solutions are easier to swallow, especially for children and elderly. The dissolved drug is spread evenly throughout the preparation, ensuring consistent dosage.

Choosing the Right Solvent for Solutions

The most common solvent for solutions is water, but other solvents like alcohol, glycerin, and propylene glycol can be used to enhance solubility and stability.

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Safety and Removal of Toxic Solvents

Solvents like acetone and ethyl oxide are recognized for extraction but must be completely removed for oral use. This ensures patient safety.

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Liquid Drug Forms: Solutions & Syrups

Liquid drug forms specifically designed for easy administration, often containing flavors and colorings to make them more palatable. They are often packaged in convenient volumes, like 5mL or 15mL, and sometimes with droppers for children.

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Dry Powder for Solution

A dry powder mixture designed to be mixed with a solvent (usually water) to form a liquid solution. This allows unstable medications to be stored in a stable form until ready for use.

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Syrup

A type of liquid medication that is a concentrated aqueous solution of sugar or a sugar substitute, often with added flavors and medicinal substances.

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Non-Medicated Syrups

Syrups that do not contain any medicinal substances. They are used as flavoring agents for the extemporaneous compounding of medications.

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Medicated Syrups

Syrups that contain medicinal substances dissolved in a flavored syrup base. They are used to administer disagreeable-tasting drugs in a more palatable form.

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Sugar in Syrups

A type of sugar, either sucrose or a non-sucrose alternative, that is used in syrups to provide sweetness and viscosity.

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Antimicrobial Preservatives in Syrups

An ingredient added to syrups to prevent microbial growth and ensure their stability, extending shelf life.

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Tinctures

Liquid preparations made from vegetable materials or chemicals, often used for preservation and therapeutic purposes.

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Oral Solution

A solution used for administering medicine orally, usually in small doses.

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Simple Solutions

Simple liquid preparations containing dissolved drugs, intended for oral use.

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Topical Solutions

Solutions used for topical application, often formulated for specific uses like pain relief or infections.

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Oral Medications

Substances used in the mouth for various purposes: anesthesia, infection control, diagnosis, pain relief, and prevention.

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Mouthwashes and Gargles

Concentrated liquid preparations for gargling or mouthwashing, not intended for swallowing.

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Vaginal Douches

Solutions for vaginal irrigation, cleaning, and treatment.

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Powders and Solutions for Douching

Solutions prepared from powders, liquids, or liquid solutions, used for various purposes, including irrigation and treatment.

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Special/co-solvents, solubilizing agents, thickeners, stabilizers

Substances added to solutions to improve solubility, viscosity, or stability.

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Sucrose

The most common sugar used in syrups, providing sweetness and viscosity.

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Glycogenetic substances

Substances that can replace sucrose in syrups, including sorbitol, glycerin, and propylene glycol. These are often used in sugar-free or diabetic formulations.

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Non-glycogenetic materials

Substances that can replace sucrose in syrups, including methylcellulose and hydroxy ethylcellulose. These are not broken down by the body and are ideal for diabetic or sugar-restricted patients.

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Viscosity of a syrup

The desired sweetness and viscosity of a syrup are important for its intended taste.

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Syrup concentration

Syrups are typically 60-80% sucrose to achieve optimal stability and viscosity.

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Syrup, NF (USP) or simple syrup

A standard reference syrup used in pharmacy that consists of 85 g of sucrose dissolved in enough water to make 100 mL. It is inherently stable and requires no additional preservation.

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Stability of concentrated syrups

The relative absence of water in concentrated syrups contributes to their stability and resistance to microbial growth.

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Physical stability of syrups

Adding a small amount of water to a syrup can improve its physical stability and resistance to crystallization.

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Related Documents

Solutions part 1.PDF

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