Pharmaceutical Solutions Dosage Forms Quiz

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Questions and Answers

Which of the following is a disadvantage of pharmaceutical solutions?

They are more quickly effective than tablets and capsules

They dilute the irritant action of some drugs

They give a uniform dose than suspension because no need for shaking

Unpleasant taste or odor are difficult to mask (correct)

In which of the following routes of administration are syrups, elixirs, and drops used?

In mouth and throat

On body surfaces

In body cavities

Orally (correct)

What problem of drugs in solution dosage forms can be initiated by heat, light, peroxides, or heavy metals?

Autoxidation (correct)

Bulky to carry around

Less stable than solid dosage forms

Unpleasant taste or odor

Which of the following is an advantage of pharmaceutical solutions related to swallowing difficulty in children and some adults?

Easy to swallow as children and some adults have difficulty in swallowing solid tablets and capsules Signup and view all the answers

Which of the following is a disadvantage of pharmaceutical solutions related to stability?

They are less stable than solid dosage forms Signup and view all the answers

What is one of the problems associated with pharmaceutical solutions being bulky to carry around?

They are bulky to carry around Signup and view all the answers

What problem can arise due to hydrolysis in pharmaceutical solutions?

Decreased stability in aqueous medium Signup and view all the answers

What can be used to minimize the effect of trace metals in pharmaceutical solutions?

Citric acid or EDTA Signup and view all the answers

Why should plastic containers not be used if a light-resistant container is specified?

They may alter product pH Signup and view all the answers

What can be carriers of bacteria that ultimately contaminate pharmaceutical products?

Surfactants, sugars, and flavors Signup and view all the answers

Where do bacteria grow well in pharmaceutical equipment?

Nooks and crevices Signup and view all the answers

What is the most important carrier of contaminants contributing to product contamination?

Hands and hair Signup and view all the answers

Which type of preservative is effective in acid media due to its non-ionized form?

Acids Signup and view all the answers

What is the concentration range for benzoic acid as a preservative?

0.1% to 0.5% Signup and view all the answers

Which esters are employed at concentrations up to 0.2% as preservatives?

Parabens Signup and view all the answers

What is propylene glycol used as in pharmaceutical preparations?

Solvent in oral solutions and topical preparations Signup and view all the answers

Study Notes

Disadvantages of Pharmaceutical Solutions

Instability of drugs in solution dosage forms can be initiated by heat, light, peroxides, or heavy metals.
Pharmaceutical solutions can be bulky to carry around, which can be a problem.
Solutions can be susceptible to hydrolysis, which can lead to degradation.

Advantages of Pharmaceutical Solutions

Pharmaceutical solutions can be an advantage for people with swallowing difficulties, such as children and some adults.

Routes of Administration

Syrups, elixirs, and drops are used in the oral route of administration.

Stability Issues

Pharmaceutical solutions can be prone to degradation due to stability issues, which is a disadvantage.

Minimizing Contamination

Chelating agents can be used to minimize the effect of trace metals in pharmaceutical solutions.
Plastic containers should not be used if a light-resistant container is specified, as they may allow light to penetrate and affect the solution.
Water and other liquids can be carriers of bacteria that ultimately contaminate pharmaceutical products.
Moist areas, such as pipes and valves, are where bacteria grow well in pharmaceutical equipment.
People are the most important carrier of contaminants contributing to product contamination.

Preservatives

Benzoic acid is a type of preservative that is effective in acid media due to its non-ionized form, and is used in a concentration range of 0.05-0.1%.
Paraben esters are employed at concentrations up to 0.2% as preservatives.
Propylene glycol is used as a solvent, humectant, and preservative in pharmaceutical preparations.

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Description

Test your knowledge about pharmaceutical solutions, including their formulation for different routes of administration and advantages. Learn about dosage forms such as syrups, drops, mouth washes, douches, and their benefits.