Podcast
Questions and Answers
What is the main characteristic of a lead compound?
What is the main characteristic of a lead compound?
- It has optimal pharmacokinetic properties
- It has the desired pharmaceutical activity (correct)
- It is synthesized from a natural source
- It has no side effects
What is the primary purpose of a drug discovery program?
What is the primary purpose of a drug discovery program?
- To improve the pharmacodynamic properties of a lead compound
- To eliminate all side effects of a lead compound
- To identify a lead compound with optimal pharmacokinetic properties
- To discover a new drug through a series of programmed searches (correct)
What is the purpose of lead optimization?
What is the purpose of lead optimization?
- To eliminate patent restrictions
- To reduce the daily dose of a lead compound
- To improve the therapeutic properties of a lead compound (correct)
- To modify the structure of a lead compound
What is the outcome of modifying the structure of a lead compound?
What is the outcome of modifying the structure of a lead compound?
What is the difference between extensive screening and random screening?
What is the difference between extensive screening and random screening?
What is the outcome of combining the two approaches of extensive and random screening?
What is the outcome of combining the two approaches of extensive and random screening?
Which antihistaminics were introduced in 1980 to reduce sedation?
Which antihistaminics were introduced in 1980 to reduce sedation?
Which of the following is an example of a drug that underwent extensive screening?
Which of the following is an example of a drug that underwent extensive screening?
What is the purpose of a drug discovery program's first task?
What is the purpose of a drug discovery program's first task?
What is the primary goal of modifying a lead compound's structure?
What is the primary goal of modifying a lead compound's structure?
What is the primary difference between a lead compound and a fully optimized drug?
What is the primary difference between a lead compound and a fully optimized drug?
Which of the following is a characteristic of a random screening approach?
Which of the following is a characteristic of a random screening approach?
What is the primary advantage ofcombining extensive and random screening approaches?
What is the primary advantage ofcombining extensive and random screening approaches?
Which of the following is an example of a pharmaceutical activity that may be improved during lead optimization?
Which of the following is an example of a pharmaceutical activity that may be improved during lead optimization?
What is the primary goal of a lead optimization process?
What is the primary goal of a lead optimization process?
What is the outcome of improving the pharmacokinetic properties of a lead compound?
What is the outcome of improving the pharmacokinetic properties of a lead compound?
What is the primary reason for modifying the structure of a lead compound to avoid patent restrictions?
What is the primary reason for modifying the structure of a lead compound to avoid patent restrictions?
What is the primary advantage of using a lead compound with a strong pharmaceutical activity?
What is the primary advantage of using a lead compound with a strong pharmaceutical activity?
