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Questions and Answers

What is a contraindication for administering the varicella vaccine?

  • Febrile illness
  • Use of acetaminophen
  • Use of salicylates (correct)
  • Egg allergy
  • What is the recommended treatment for local pain after vaccine administration?

  • Massage, rest, and apply heat or ice (correct)
  • Increase dietary protein
  • Aspirin
  • Antibiotics
  • Which type of vaccine contains attenuated antigens?

  • Inactivated vaccines
  • Killed vaccines
  • Live vaccines (correct)
  • Recombinant vaccines
  • Which condition requires the recombinant zoster vaccine?

    <p>History of shingles (D)</p> Signup and view all the answers

    What is the risk of administering antivenom after 4 hours of exposure?

    <p>It may not be effective. (B)</p> Signup and view all the answers

    What is a major adverse reaction to interferons?

    <p>Flu-like symptoms (B)</p> Signup and view all the answers

    Why are colony-stimulating factors used after chemotherapy?

    <p>To reduce neutropenia and infection risk (A)</p> Signup and view all the answers

    Which of the following is a potential adverse reaction to colony-stimulating factors?

    <p>Bone pain (D)</p> Signup and view all the answers

    What is treated with thrombopoietin receptor agonists?

    <p>Thrombocytopenia (A)</p> Signup and view all the answers

    Why is epoetin alpha administered to patients with CKD-related anemia?

    <p>It stimulates erythropoiesis. (B)</p> Signup and view all the answers

    Which condition poses a contraindication for darbepoetin alfa?

    <p>Hypertension (C)</p> Signup and view all the answers

    What type of anemia results from a deficiency of intrinsic factor?

    <p>Pernicious anemia (D)</p> Signup and view all the answers

    Which statement is true regarding pernicious anemia?

    <p>It requires lifelong therapy with vitamin B12. (D)</p> Signup and view all the answers

    What is a common adverse effect of oral iron supplementation?

    <p>Black or dark stools (C)</p> Signup and view all the answers

    What precaution should be observed when giving iron injections?

    <p>Avoid milk and antacids before administration. (C)</p> Signup and view all the answers

    What symptom may indicate a hypersensitivity reaction to immune globulin therapy?

    <p>Hypotension (A)</p> Signup and view all the answers

    What type of immunity is primarily associated with the action of B cells?

    <p>Humoral immunity (C)</p> Signup and view all the answers

    How does antibody production change with age in older adults?

    <p>It decreases even after vaccinations (D)</p> Signup and view all the answers

    Which statement accurately describes a key feature of cell-mediated immunity?

    <p>T cells serve as the first responders (B)</p> Signup and view all the answers

    What role do antigens play in the immune system?

    <p>Antigens stimulate the production of antibodies (A)</p> Signup and view all the answers

    What is the primary purpose of vaccines in immunization?

    <p>To stimulate active immunity through immune response (C)</p> Signup and view all the answers

    Which disease can be prevented by receiving a vaccine before traveling to endemic areas?

    <p>Cholera (B)</p> Signup and view all the answers

    What type of immunity does an immune globulin treatment provide?

    <p>Temporary passive immunity (B)</p> Signup and view all the answers

    What is the most crucial precaution for the storage of vaccines?

    <p>Refrigerate with a backup power source (B)</p> Signup and view all the answers

    What is a contraindication for receiving interferons?

    <p>Pregnancy, unless at high risk for MS (B)</p> Signup and view all the answers

    How should folic acid be administered to treat megaloblastic anemia?

    <p>Orally, unless the patient cannot tolerate it (C)</p> Signup and view all the answers

    Which medication is used to reduce hematologic effects after methotrexate therapy?

    <p>Leucovorin (B)</p> Signup and view all the answers

    What is the primary purpose of chemotherapy in cancer treatment?

    <p>To target rapidly dividing cancer cells (B)</p> Signup and view all the answers

    What recommended action should pregnant nurses take regarding chemotherapy drugs?

    <p>Avoid preparing, administering, or handling these drugs (C)</p> Signup and view all the answers

    What adverse reaction should be monitored in patients taking temozolomide with radiation?

    <p>Pneumocystis pneumonia (B)</p> Signup and view all the answers

    What precaution is essential when administering antivenoms?

    <p>Resuscitation equipment must be available (A)</p> Signup and view all the answers

    What special precautions must pregnant nurses take regarding chemotherapy drugs?

    <p>They must avoid handling chemotherapy drugs altogether. (C)</p> Signup and view all the answers

    What temperature in a chemotherapy patient requires immediate medical reporting?

    <p>Temperature &gt;100.4°F (D)</p> Signup and view all the answers

    Which action should be taken first if extravasation occurs during IV chemotherapy?

    <p>Stop infusion immediately. (B)</p> Signup and view all the answers

    What type of anemia is caused by inadequate iron levels in the body?

    <p>Iron-deficiency anemia (B)</p> Signup and view all the answers

    Which method is recommended to minimize tooth staining when taking iron supplements?

    <p>Use a straw with juice or water. (A)</p> Signup and view all the answers

    Why should calcium intake be avoided near the time of iron supplement intake?

    <p>Calcium reduces iron absorption. (A)</p> Signup and view all the answers

    What is a key precaution when administering antivenoms?

    <p>Check for an allergy to equine serum. (C)</p> Signup and view all the answers

    Which adverse reaction is commonly associated with interferons?

    <p>Flu-like symptoms (A)</p> Signup and view all the answers

    Which group is at increased risk of severe herpes zoster reoccurrence?

    <p>Older adults (C)</p> Signup and view all the answers

    What precaution should be taken when administering vitamin B12 injections?

    <p>Monitor for pulmonary edema. (C)</p> Signup and view all the answers

    What is the primary treatment for megaloblastic anemia?

    <p>Folic acid administration (D)</p> Signup and view all the answers

    What should be avoided within two hours of taking oral iron supplements?

    <p>High-calcium meals (C)</p> Signup and view all the answers

    What is a contraindication for human immune globulin intravenous (IVIG)?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the role of toxoids in immunization?

    <p>They stimulate the body to produce antitoxins. (D)</p> Signup and view all the answers

    Which of the following is not advised when administering vitamin B12 injections?

    <p>Administer in the abdomen. (D)</p> Signup and view all the answers

    Which dietary component can cause interference with iron absorption?

    <p>High-calcium meals (A)</p> Signup and view all the answers

    Flashcards

    Humoral Immunity

    Immune response involving B cells producing antibodies against antigens.

    Antibody Production in Older Adults

    Decreases, even after vaccinations, making them more susceptible to infections.

    Cell-mediated Immunity (CMI)

    Immune response where T cells are the initial responders to fight infection.

    Antigens

    Substances (usually proteins) that trigger the body to produce antibodies.

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    Vaccines

    Substances that stimulate the body's immune response to create active immunity.

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    Vaccine for Cholera

    Vaccine recommended before travel to endemic areas.

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    Immune Globulin

    Provides passive immunity for short-term, immediate protection.

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    Vaccine Storage

    Refrigerate and have a backup power source to maintain vaccine potency.

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    Varicella vaccine contraindication

    Using salicylates with the varicella vaccine increases the risk of Reye's Syndrome.

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    Post-vaccine pain treatment

    Massage, rest, and applying heat or ice are recommended for local vaccine pain.

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    Live vaccines

    Use weakened antigens to stimulate an immune response.

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    Recombinant Zoster Vaccine

    Recommended for adults with a history of shingles.

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    Antivenom effectiveness

    Administering antivenom promptly maximizes effectiveness; 4 hours post-exposure is a critical window.

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    Interferon adverse reaction

    Interferons commonly cause flu-like symptoms (chills, fever, malaise).

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    Colony-stimulating factors and chemotherapy

    Used after chemotherapy to reduce neutropenia and infection risk by boosting neutrophil production.

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    Thrombocytopenia treatment

    Thrombopoietin receptor agonists stimulate platelet production to treat a low platelet count.

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    CKD-related anemia treatment

    Epoetin alpha stimulates red blood cell production to manage kidney disease anemia.

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    Darbepoetin alfa contraindication

    Uncontrolled high blood pressure (hypertension) is a reason not to use darbepoetin alfa.

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    Pernicious anemia cause

    Pernicious anemia is caused by a lack of intrinsic factor, which prevents vitamin B12 absorption.

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    Pernicious anemia treatment

    Pernicious anemia requires lifelong B12 therapy.

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    Oral iron side effect

    Dark stools are a common side effect from taking oral iron supplements.

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    Iron injection precaution

    Avoid milk and antacids before injecting iron to improve absorption.

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    Immune globulin hypersensitivity

    Hypotension (low blood pressure) is a possible reaction to immune globulin.

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    Cyanosis during Immune Globulin

    Cyanosis, or a bluish discoloration of the skin, can be a sign of hypersensitivity reaction during immune globulin therapy.

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    Interferons and Pregnancy

    Interferons are generally contraindicated during pregnancy, unless the risk of MS outweighs the potential harm to the fetus.

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    Folic Acid Administration

    Folic acid is usually given orally, unless the patient has difficulty absorbing it through the digestive system.

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    Leucovorin and Methotrexate

    Leucovorin is used to reduce the negative hematologic effects (effects on blood cells) of methotrexate therapy.

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    Chemotherapy's Target

    Chemotherapy drugs target rapidly dividing cells, including cancer cells, aiming to slow down tumor growth.

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    Pregnant Nurses and Chemotherapy

    Pregnant nurses should avoid handling chemotherapy drugs due to the potential harm it can cause to the developing fetus.

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    Temozolomide and Radiation Risk

    Patients taking temozolomide with brain radiation are at higher risk of developing pneumocystis pneumonia, a lung infection.

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    Antivenom Administration

    Antivenom administration requires immediate access to resuscitation equipment, as severe allergic reactions can occur.

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    Chemotherapy Drug Precautions

    Pregnant nurses should avoid handling chemotherapy drugs due to the risk of birth defects (teratogenicity).

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    Chemotherapy Fever: Red Flag!

    A fever in a chemotherapy patient (above 100.4°F) requires immediate medical attention, as it could indicate a serious infection.

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    Extravasation: Stop!

    If chemotherapy drugs leak out of the vein (extravasation), stop the infusion immediately.

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    Iron-deficiency Anemia

    Anemia caused by a lack of iron in the body, leading to insufficient hemoglobin production.

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    Iron Supplements: Straw Trick

    Drink iron supplements through a straw to minimize the risk of tooth staining.

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    Calcium and Iron: Timing Matters

    Calcium should be taken at a different time from iron supplements, as it interferes with the body's absorption of iron.

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    Antivenom Allergy?

    Antivenoms are a contraindication for patients with an allergy to equine (horse) serum, as it can cause severe reactions.

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    Interferons and Flu-like Symptoms

    Interferons often cause flu-like symptoms such as chills, fever, headache, and malaise.

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    Shingles Recurrence Risk

    Older adults, especially those with a history of shingles, have an increased risk of shingles recurring.

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    Vitamin B12 Injection Precaution

    Administering vitamin B12 injections can cause pulmonary edema, a serious condition where fluid builds up in the lungs.

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    Megaloblastic Anemia Treatment

    Megaloblastic anemia, caused by a lack of folic acid, is treated with folic acid supplements.

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    Iron Absorption Interference

    High-calcium meals can block the absorption of iron supplements, making them less effective.

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    IVIG Contraindication

    Human immune globulin intravenous (IVIG) is not given to people with diabetes, those older than 65, or those taking nephrotoxic drugs due to risks of kidney damage.

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    Toxoid Function

    Toxoids are weakened toxins used in vaccines to stimulate the body's production of antitoxins, which neutralize harmful substances.

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    What is toxoid used for?

    Toxoids are weakened toxins used in vaccines to stimulate the body's production of antitoxins, which neutralize harmful substances.

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    Why are toxoids used in vaccines?

    Toxoids are weakened toxins used in vaccines to stimulate the body's production of antitoxins, which neutralize harmful substances.

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    Study Notes

    Pharm Exam Questions and Answers

    • Question 1: Which type of immunity is associated with B cells?

      • Humoral immunity
    • Question 2: What happens to antibody production in older adults?

      • It decreases, even after vaccinations.
    • Question 3: Which characteristic describes cell-mediated immunity (CMI)?

      • Involves T cells as first responders
    • Question 4: Which statement about antigens is true?

      • Antigens stimulate the production of antibodies.
    • Question 5: What is the primary role of vaccines?

      • To stimulate the immune response and create active immunity
    • Question 6: Which disease is preventable by vaccination before traveling to endemic areas?

      • Cholera
    • Question 7: What kind of immunity does immune globulin provide?

      • Passive immunity with short duration
    • Question 8: What is the primary precaution for storing vaccines?

      • Refrigerate and have a backup power source
    • Question 9: What is a contraindication for administering the varicella vaccine?

      • Use of salicylates
    • Question 10: What is the recommended treatment for local pain after vaccine administration?

      • Massage, rest, and apply heat or ice
    • Question 11: What type of vaccine contains attenuated antigens?

      • Live vaccines
    • Question 12: Which condition requires the recombinant zoster vaccine?

      • History of shingles
    • Question 13: What is the risk of administering antivenom after 4 hours of exposure?

      • It may not be effective.
    • Question 14: What is a major adverse reaction to interferons?

      • Flu-like symptoms
    • Question 15: Why are colony-stimulating factors used after chemotherapy?

      • To reduce neutropenia and infection risk
    • Question 16: Which of the following is a potential adverse reaction to colony-stimulating factors?

      • Bone pain
    • Question 17: Which condition is treated using thrombopoietin receptor agonists?

      • Thrombocytopenia
    • Question 18: Why is epoetin alpha used in patients with CKD-related anemia?

      • It stimulates erythropoiesis.
    • Question 19: What is a contraindication for using darbepoetin alfa?

      • Hypertension
    • Question 20: What type of anemia results from a lack of intrinsic factor?

      • Pernicious anemia
    • Question 21: Which of the following is true about pernicious anemia?

      • It requires lifelong therapy with vitamin B12.
    • Question 22: What is a common adverse reaction to oral iron supplementation?

      • Black or dark stools
    • Question 23: What precaution should be taken when administering iron injections?

      • Inject into fatty tissue.
    • Question 24: Which symptom indicates a hypersensitivity reaction to immune globulin therapy?

      • Cyanosis
    • Question 25: What is a contraindication for receiving interferons?

      • Pregnancy
    • Question 26: How should folic acid be administered to treat megaloblastic anemia?

      • Orally, unless the patient cannot tolerate it
    • Question 27: Which medication is used to reduce hematologic effects after methotrexate therapy?

      • Leucovorin
    • Question 28: What is the role of chemotherapy in cancer treatment?

      • To target rapidly dividing cancer cells
    • Question 29: What is the recommended action for pregnant nurses regarding chemotherapy drugs?

      • Avoid preparing, administering, or handling these drugs.
    • Question 30: What adverse reaction should be monitored in patients taking temozolomide with radiation?

      • Pneumocystis pneumonia
    • Question 31: What precaution is essential when administering antivenoms?

      • Resuscitation equipment must be available.
    • Question 32: What type of immunity do immune globulins provide?

      • Passive, short-term immunity
    • Question 33: Which of the following is an example of a live attenuated vaccine?

      • Measles, Mumps, Rubella (MMR)
    • Question 34: What is the function of colony-stimulating factors (CSFs)?

      • Promote WBC production to combat neutropenia.
    • Question 35: What is the role of thrombopoietin receptor agonists?

      • Elevate platelet counts
    • Question 36: Which adverse reaction is most associated with interferons?

      • "Flu-like symptoms"
    • Question 37: What should be avoided when administering interferons?

      • Live-attenuated vaccines
    • Question 38: When should colony-stimulating factors be started after chemotherapy?

      • 24 hours
    • Question 39: What is a common adverse reaction to epoetin alpha?

      • Hypertension
    • Question 40: What dietary component can interfere with iron absorption?

      • High-calcium meals
    • Question 41: Which vaccine is recommended for adults with a history of shingles?

      • Recombinant zoster vaccine
    • Question 42: What is an adverse reaction associated with antivenoms?

      • Pruritus
    • Question 43: What precaution is required for administering vaccines stored in refrigeration?

      • Always have a backup storage plan for power outages.
    • Question 44: What should be avoided while receiving oral iron therapy?

      • Dairy products
    • Question 45: Which lab parameter is crucial for monitoring during CSF therapy?

      • Absolute neutrophil count (ANC)
    • Question 46: What is the target hemoglobin level for patients receiving epoetin alpha therapy?

      • 11 g/dL
    • Question 47: What type of anemia requires lifelong vitamin B12 therapy?

      • Pernicious anemia
    • Question 48: What dietary deficiency causes megaloblastic anemia?

      • Vitamin B12 or folic acid
    • Question 49: What is the role of leucovorin in folic acid deficiency?

      • Mitigates hematologic effects of methotrexate.
    • Question 50: Why is a test dose required before administering iron dextran?

      • To check for anaphylactic reactions.
    • Question 51: What is a contraindication for darbepoetin alfa?

      • Uncontrolled hypertension
    • Question 52: What condition is treated with interferons?

      • Multiple sclerosis
    • Question 53: What is a key side effect of colony-stimulating factors?

      • Bone pain
    • Question 54: What is the primary use of antimetabolite drugs in chemotherapy?

      • Targeting the cell cycle
    • Question 55: What nursing precaution is necessary for chemotherapy handling?

      • Pregnant nurses should avoid handling chemotherapy drugs.
    • Question 56: What adverse reaction requires immediate reporting in a chemotherapy patient?

      • Temperature >100.4°F
    • Question 57: What should be done if extravasation occurs during IV chemotherapy?

      • Stop infusion immediately.
    • Question 58: What anemia results from inadequate iron levels in the body?

      • Iron-deficiency anemia
    • Question 59: What method is best for administering iron supplements to minimize tooth staining?

      • Use a straw with juice or water.
    • Question 60: Why is calcium avoided near the time of iron supplement intake?

      • It binds to iron, reducing absorption.
    • Question 61: What is the main precaution for administering antivenoms?

      • Check for an allergy to equine serum.
    • Question 62: What adverse reaction is commonly associated with interferons?

      • Flu-like symptoms
    • Question 63: What monitoring is essential for colony-stimulating factors used in neutropenia?

      • Absolute neutrophil count (ANC)
    • Question 64: What is a major adverse reaction of thrombopoietin receptor agonists?

      • Vision disturbances (cataract formation)
    • Question 65: What type of immunity involves B cells and antibody production?

      • Humoral immunity
    • Question 66: Why should salicylates be avoided with the varicella vaccine?

      • They increase the risk of Reye's syndrome.
    • Question 67: What is the primary action of erythropoiesis-stimulating agents?

      • Promote red blood cell production
    • Question 68: Which adverse reaction is commonly associated with chemotherapy?

      • Bone marrow suppression
    • Question 69: What is the ideal storage condition for vaccines?

      • Refrigerated with a backup plan for power outages
    • Question 70: Which group is at increased risk of severe herpes zoster reoccurrence?

      • Older adults
    • Question 71: What precaution should be taken when administering vitamin B12 injections?

      • Monitor for pulmonary edema.
    • Question 72: What is the primary treatment for megaloblastic anemia?

      • Folic acid administration
    • Question 73: What should be avoided within two hours of taking oral iron supplements?

      • High-calcium meals
    • Question 74: What is a contraindication for human immune globulin intravenous (IVIG)?

      • Use of nephrotoxic drugs
    • Question 75: What is the role of toxoids in immunization?

      • They stimulate the body to produce antitoxins

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    Test your knowledge with these exam questions focused on immunology as it relates to pharmaceuticals. Covering topics such as types of immunity, the role of vaccines, and antibody production, this quiz is essential for pharmacy students or practitioners. Enhance your understanding and preparation for your pharmacology exams.

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