PHAR 141G Pharmaceutics: Drug Dosage Form and Delivery System Design (I)
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Questions and Answers

What is the primary characteristic of gas molecules?

  • High density and visible appearance
  • Regular shape and low compressibility
  • Rapid motion and random movement (correct)
  • Low intermolecular forces of attraction

    • What is the general gas equation for an ideal gas?

  • $P = mRT/n$
  • $P = nRT/m$
  • $P = mRT/V$
  • $P = nRT/V$ (correct)

    • What is the molar gas constant (R) in the ideal gas law equation?

  • 0.082 L·atm/mol·K
  • 0.082 L·bar/mol·K
  • 0.082 L·atm/mol·deg (correct)
  • 0.082 L·bar/mol·deg

    • What is the main pharmaceutical application of compressed gases?

    <p>Oxygen, nitrogen, and carbon dioxide</p> Signup and view all the answers

    What is the primary driver for the hydrophobic interaction?

    <p>Hydrophobic effect</p> Signup and view all the answers

    What is the primary role of hydrophobic interactions in biomolecules?

    <p>Forming the tertiary structure of proteins</p> Signup and view all the answers

    Why are dosage forms needed?

    <p>To provide a mechanism for the safe and convenient delivery of accurate dosage</p> Signup and view all the answers

    What does preformulation involve?

    <p>Determining and defining physical and chemical properties important for formulation</p> Signup and view all the answers

    Why is understanding basic chemistry important in drug design?

    <p>It contributes to the physicochemical properties and uses of the drug</p> Signup and view all the answers

    Which of the following is NOT a parameter involved in a drug's physiological availability and stability?

    <p>Drug over-the-counter availability</p> Signup and view all the answers

    What is the purpose of studying preformulation studies?

    <p>To optimize a drug for stable, effective, and safe dosage form</p> Signup and view all the answers

    How does distinguishing between gaseous, liquid, and solid states of matter relate to drug design?

    <p>It is crucial in selecting the appropriate state for drug formulation</p> Signup and view all the answers

    What determines the size and molecular weight of polymers?

    <p>Number of repeating units</p> Signup and view all the answers

    Which type of polymers include rubber, polypeptides, and cellulose?

    <p>Natural polymers</p> Signup and view all the answers

    What is the role of Carbomer in formulations?

    <p>Thickening agent</p> Signup and view all the answers

    What does HPMC polymer commonly serve as in pharmaceutical applications?

    <p>Tablet coating</p> Signup and view all the answers

    In what state of matter do gaseous substances exert pressure and occupy volume?

    <p>Gas</p> Signup and view all the answers

    Which of the following forces are responsible for separating molecules?

    <p>Repulsive forces</p> Signup and view all the answers

    When repulsive forces and attractive forces are equal, what state does the system achieve?

    <p>Equilibrium and minimum potential energy</p> Signup and view all the answers

    Which of the following intermolecular interactions is involved in the formation of iodine solutions containing the iodide complex (I2 + K+I- = K+I3-)?

    <p>Ion-dipole and ion-induced dipole interactions</p> Signup and view all the answers

    Which of the following intermolecular interactions is the strongest?

    <p>Ionic bonds</p> Signup and view all the answers

    Which of the following intermolecular interactions is involved in the solubility of some drugs?

    <p>Van der Waals forces</p> Signup and view all the answers

    Which of the following surfactants is mentioned in the given text?

    <p>Sodium lauryl sulfate</p> Signup and view all the answers

    What type of bond is present in metallic solids?

    <p>Metallic bond</p> Signup and view all the answers

    Which of the following is a characteristic of crystalline solids?

    <p>Regularly repeating pattern with fixed molecular orders</p> Signup and view all the answers

    What is the term used for a crystalline solid that has solvent molecules trapped within its crystal structure?

    <p>Solvate</p> Signup and view all the answers

    Which of the following factors can influence the formation of different polymorphs of a crystalline solid?

    <p>All of the above</p> Signup and view all the answers

    Which of the following properties can differ between polymorphs of a crystalline solid?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is an example of a crystalline solid that exhibits polymorphism?

    <p>All of the above</p> Signup and view all the answers

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