29 Questions
What is the primary characteristic of gas molecules?
Rapid motion and random movement
What is the general gas equation for an ideal gas?
$P = nRT/V$
What is the molar gas constant (R) in the ideal gas law equation?
0.082 L·atm/mol·deg
What is the main pharmaceutical application of compressed gases?
Oxygen, nitrogen, and carbon dioxide
What is the primary driver for the hydrophobic interaction?
Hydrophobic effect
What is the primary role of hydrophobic interactions in biomolecules?
Forming the tertiary structure of proteins
Why are dosage forms needed?
To provide a mechanism for the safe and convenient delivery of accurate dosage
What does preformulation involve?
Determining and defining physical and chemical properties important for formulation
Why is understanding basic chemistry important in drug design?
It contributes to the physicochemical properties and uses of the drug
Which of the following is NOT a parameter involved in a drug's physiological availability and stability?
Drug over-the-counter availability
What is the purpose of studying preformulation studies?
To optimize a drug for stable, effective, and safe dosage form
How does distinguishing between gaseous, liquid, and solid states of matter relate to drug design?
It is crucial in selecting the appropriate state for drug formulation
What determines the size and molecular weight of polymers?
Number of repeating units
Which type of polymers include rubber, polypeptides, and cellulose?
Natural polymers
What is the role of Carbomer in formulations?
Thickening agent
What does HPMC polymer commonly serve as in pharmaceutical applications?
Tablet coating
In what state of matter do gaseous substances exert pressure and occupy volume?
Gas
Which of the following forces are responsible for separating molecules?
Repulsive forces
When repulsive forces and attractive forces are equal, what state does the system achieve?
Equilibrium and minimum potential energy
Which of the following intermolecular interactions is involved in the formation of iodine solutions containing the iodide complex (I2 + K+I- = K+I3-)?
Ion-dipole and ion-induced dipole interactions
Which of the following intermolecular interactions is the strongest?
Ionic bonds
Which of the following intermolecular interactions is involved in the solubility of some drugs?
Van der Waals forces
Which of the following surfactants is mentioned in the given text?
Sodium lauryl sulfate
What type of bond is present in metallic solids?
Metallic bond
Which of the following is a characteristic of crystalline solids?
Regularly repeating pattern with fixed molecular orders
What is the term used for a crystalline solid that has solvent molecules trapped within its crystal structure?
Solvate
Which of the following factors can influence the formation of different polymorphs of a crystalline solid?
All of the above
Which of the following properties can differ between polymorphs of a crystalline solid?
All of the above
Which of the following is an example of a crystalline solid that exhibits polymorphism?
All of the above
This quiz covers the basics of drug dosage forms and drug delivery system design in pharmaceutical sciences. Topics include the need for dosage forms, understanding basic chemistry of molecules, bonds, and their contribution to drug properties.
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